ID A0A0V0ZXP8_9BILA Unreviewed; 2623 AA.
AC A0A0V0ZXP8;
DT 16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT 16-MAR-2016, sequence version 1.
DT 24-JAN-2024, entry version 17.
DE RecName: Full=FMP27/BLTP2/Hobbit GFWDK motif-containing RBG unit domain-containing protein {ECO:0000259|SMART:SM01214};
GN ORFNames=T12_2701 {ECO:0000313|EMBL:KRY16883.1};
OS Trichinella patagoniensis.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Enoplea; Dorylaimia;
OC Trichinellida; Trichinellidae; Trichinella.
OX NCBI_TaxID=990121 {ECO:0000313|EMBL:KRY16883.1, ECO:0000313|Proteomes:UP000054783};
RN [1] {ECO:0000313|EMBL:KRY16883.1, ECO:0000313|Proteomes:UP000054783}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ISS2496 {ECO:0000313|EMBL:KRY16883.1};
RA Korhonen P.K., Edoardo P., Giuseppe L.R., Gasser R.B.;
RT "Evolution of Trichinella species and genotypes.";
RL Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KRY16883.1}.
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DR EMBL; JYDQ01000071; KRY16883.1; -; Genomic_DNA.
DR Proteomes; UP000054783; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0046873; F:metal ion transmembrane transporter activity; IEA:InterPro.
DR InterPro; IPR019443; BLTP2/FMP27/Hobbit_C.
DR InterPro; IPR048872; BLTP2_RBG6.
DR InterPro; IPR019441; FMP27/BLTP2/Hobbit_GFWDK_RBG.
DR InterPro; IPR045167; Hobbit.
DR InterPro; IPR003689; ZIP.
DR PANTHER; PTHR15678; ANTIGEN MLAA-22-RELATED; 1.
DR PANTHER; PTHR15678:SF6; PROTEIN KIAA0100; 1.
DR Pfam; PF21675; BLTP2_RBG-6; 1.
DR Pfam; PF10351; FMP27-BLTP2_C; 1.
DR Pfam; PF10347; Fmp27_GFWDK; 1.
DR Pfam; PF02535; Zip; 1.
DR SMART; SM01214; Fmp27_GFWDK; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000054783};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 41..62
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 74..99
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 119..144
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 204..224
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 262..284
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 296..318
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 330..356
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 1301..1433
FT /note="FMP27/BLTP2/Hobbit GFWDK motif-containing RBG unit"
FT /evidence="ECO:0000259|SMART:SM01214"
FT REGION 1963..2062
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2441..2462
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 2214..2272
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 1963..1988
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 2623 AA; 299391 MW; F1BD162E323105FA CRC64;
MMFNILLPCT IKTISETKRD NDNFDATEFN YYRLSVFNSV FSVRLLLLTI ISSILPLWFR
RLALQPSSTR RRLFVSYIFS VLSCFGGGVF LGTCILDLLP DTREVLDGVL YELFEEQSSF
PLAEFFAAIG FSLILCIEQV VLYLRNSHFH YDNVTDIVET LETTDDENRP LLDERKLRRR
YSLVSDSGEE VHVDPWSHSA LRALLMLLTL STHALFEGLA LGLINDSTQA VQIFTALSIH
KSLVGFSLGL RLVSFPTLSN LMIVLSCLAF SATGCMGGLI GLILSETLRS KVAKLITGAL
QGVACGTFLY IVTFEILPHE LSATIQYTPL KLFSFILGLG TISFLLQITN LFLFAFSKAF
NCGSISIDRF GFFYVEGLKF RFHTICMEVD RVWLKISPKC GSFCSQLLAF HKNLVLCFGY
VRIEGAAAEF PNSRRPASQW ARLPVRALLQ AFQTVGVEMN SFNVALLDTF PGFLVHLAVE
GVVLYPLKTT DTNCSRHGRL KLLTFKVLRR PSTFSAISAP LDWFTLTSSV DFSFVSGVDI
ALPNHIQFDF CNPLASFSYD CIVLLCGRLR GMTKSAGKTG SDNLSALYRQ VLETNLDINV
CNMLLQFYSE DFNLLKLEIM QASCKKTKPN ENVSYLIQCC DLVLKGILPR SVKLQVRRLE
WCSSTARGGS VENFGSSLLT EDVRAIFAYN SLIQWWLVGL KIRKTLRTAF GQTSKWEKKN
FSRLRSVNIH NCTVLLHMPD NVNIQFMLAK AFLSKRRNSK IEIGFHSFYM DFSFGYDGNL
SASRSTPKTH VWGNCSTFGG SLIELNKDGD RYKCRAVFKA VDLEYRQAWI WALWRLVDQL
PASFENESHS KSSGQLLTSW FSSWDLSVEY LKIFIPCFDV ELCGYIVAER VKFSTNSDNT
QQQSFHCSAD TLKSGYMEIP SPSTGVELDS MRVKNKHESR LFGFSFFLNR QQKRVAVTVE
RNVRLNWSPV LHMIFLNVYK SANAFCAFVN NNNANHRQKN NKQKWKQKKE NKGGDFFEYW
NSFEIALLFD NGLCVQFNFP EQHELQFNFS SLKIAYLDDV PQFETCSVSL ICDNYPIFLF
KDVNVEKRAN YEPFVLIRQS NESLQTKTNS CWIWKISTLS ICNTWKWLRS LHFNNPTGTV
LFSDWHIKIQ SFSLELCDDP FEVKLNDNYM LMMDECCEAH RRHAILKRRL ARRNVASPFY
PKSDEHELYM GLQRKNASIY IQRSNTLYNG KPSRTGLFTW YVDFVDLVVI ADSGLFGSEK
LSSEIRTLDA DSPWPWNPSF GILFGRYVDF HFDKLFARMR DYPLPYLDVS DCSIRGKLIG
CEMKGDENSE QEFNFVVGHK FGDVTLRHFL ALLKYFYDLN TVIGELRWTY GPCWDPCLSM
ISACWELVNR PSLDPSPRLP FWDRIRLLLH GRLRVRCGQV VTSILASADP YNGTERLECT
WDQLILEWTN GVVMLKCDFD MSVRTASKYD DCQLLHVPKC KMIMRMDWIC CGNPNNHYAV
VLCAPNKLPN RTDDQPHDSY RQFRSSHLNI SLVIDVQGEE CLPEAQFYTN TFRWLARLRN
TISAINRPIR RGPLYKNIRA PRAQLSRHYK SVVFLIKFPK FFVTYRPSFS TNKGVRLTCE
ALRFHTAFQL HFESSPSTPN LRRRKRMKIA TDFTDAEAKQ VDVHVFSNCK LEEIEERKSF
LIGVEKLAYF RELTALKRDN PVSFVSSKAF RHLTKQQTLP VVDLHLQAMT HKVSVYNVRG
IWTEYNRDIV LWIYDNVQKS QTLRRNLSTQ ATKPLLTGSR EMVGLLEPKF EGSVEVDPTE
IVTPPSNMES EMLQQLITES NLKSVAYCEE NADSKTDDLV GVGMSSDSDV VFTKWQVELV
NVQVALRGCN SSGYLLCTAA HGKLTLRKHR PAWRGSQLLD KSTLIATLSG MQYYATVDGD
EQESCHSTAG NWGRSPSSSC GADTALSLSV LDDEPSVCCS YSRLSSSSSS SSSSSSSSSS
SLSSSDACCE PSPAPGKCRS LGSLVSPPSP TDDGHRSVGD LRCGVGRVPL LHPDDDDDDD
DGDDDVDFDR RSNAEAGDVP SRRADQIQWL TKELVQENVN CAKNAFDVVV QRVIDEAHSA
GGVIPESAMQ GGKLQRIISR CSCEVRISSF SENFDAAELE KFLVKLENNH KESEYDPADC
VTVIHPTLTI YTSSSQYYMI LDIVNNLILY VDPQKKKSAE KLQKFRFEVQ LLGRERLRSN
ILVLQNEARL LIAKNKAREL ELYHCMQHML DNDKFEERFA LLEKLLEESK ELLAAKSDDL
HMAISCLKEK QLHRNRRPLG NRERSDLQSA VARRFEVSLQ EVQWYLTEAN GQLGLAEIQL
QKFLYTKVSR INDSGEHVLE ISKIKILNML PNSPFKEVLQ MKSENENVRK PAVSIMCREL
APVGGISVLE HFEVTVRPMH VMLTYSFFNA MMNFFFPNRS DDQHGSTSEK DGRSSSKKRK
SRFKLKLVQQ SLLPRKRWLT QESGSYLDLM KSRAAKNKFF FNIRVNEVPM NVTYKGIKSS
YIDNFKNFDL TFPLIEYNNQ NWTWLDLAMA IKSRSLRVFV NQVVKRKLLK SQITPLFKRS
KSRKGDELDE KDKKRIVLGA KLTRSFSEKN LKKTVTSTIF GEV
//
