ID A0A0V0ZZC7_9BILA Unreviewed; 2667 AA.
AC A0A0V0ZZC7;
DT 16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT 16-MAR-2016, sequence version 1.
DT 27-MAR-2024, entry version 35.
DE SubName: Full=Protocadherin-like wing polarity protein stan {ECO:0000313|EMBL:KRY17676.1};
GN Name=stan {ECO:0000313|EMBL:KRY17676.1};
GN ORFNames=T12_14422 {ECO:0000313|EMBL:KRY17676.1};
OS Trichinella patagoniensis.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Enoplea; Dorylaimia;
OC Trichinellida; Trichinellidae; Trichinella.
OX NCBI_TaxID=990121 {ECO:0000313|EMBL:KRY17676.1, ECO:0000313|Proteomes:UP000054783};
RN [1] {ECO:0000313|EMBL:KRY17676.1, ECO:0000313|Proteomes:UP000054783}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ISS2496 {ECO:0000313|EMBL:KRY17676.1};
RA Korhonen P.K., Edoardo P., Giuseppe L.R., Gasser R.B.;
RT "Evolution of Trichinella species and genotypes.";
RL Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651};
CC Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00076}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KRY17676.1}.
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DR EMBL; JYDQ01000058; KRY17676.1; -; Genomic_DNA.
DR Proteomes; UP000054783; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005509; F:calcium ion binding; IEA:UniProtKB-UniRule.
DR GO; GO:0004930; F:G protein-coupled receptor activity; IEA:UniProtKB-KW.
DR GO; GO:0009653; P:anatomical structure morphogenesis; IEA:UniProt.
DR GO; GO:0007166; P:cell surface receptor signaling pathway; IEA:InterPro.
DR GO; GO:0016043; P:cellular component organization; IEA:UniProt.
DR GO; GO:0007156; P:homophilic cell adhesion via plasma membrane adhesion molecules; IEA:InterPro.
DR CDD; cd11304; Cadherin_repeat; 8.
DR CDD; cd00054; EGF_CA; 3.
DR CDD; cd00055; EGF_Lam; 1.
DR CDD; cd00110; LamG; 1.
DR Gene3D; 2.60.120.200; -; 2.
DR Gene3D; 2.60.220.50; -; 1.
DR Gene3D; 2.60.40.60; Cadherins; 9.
DR Gene3D; 4.10.1240.10; GPCR, family 2, extracellular hormone receptor domain; 1.
DR Gene3D; 2.10.25.10; Laminin; 4.
DR InterPro; IPR039808; Cadherin.
DR InterPro; IPR002126; Cadherin-like_dom.
DR InterPro; IPR015919; Cadherin-like_sf.
DR InterPro; IPR020894; Cadherin_CS.
DR InterPro; IPR013320; ConA-like_dom_sf.
DR InterPro; IPR001881; EGF-like_Ca-bd_dom.
DR InterPro; IPR000742; EGF-like_dom.
DR InterPro; IPR000152; EGF-type_Asp/Asn_hydroxyl_site.
DR InterPro; IPR046338; GAIN_dom_sf.
DR InterPro; IPR017981; GPCR_2-like_7TM.
DR InterPro; IPR036445; GPCR_2_extracell_dom_sf.
DR InterPro; IPR001879; GPCR_2_extracellular_dom.
DR InterPro; IPR000832; GPCR_2_secretin-like.
DR InterPro; IPR000203; GPS.
DR InterPro; IPR001791; Laminin_G.
DR InterPro; IPR002049; LE_dom.
DR PANTHER; PTHR24027; CADHERIN-23; 1.
DR PANTHER; PTHR24027:SF422; NEURAL-CADHERIN 2-RELATED; 1.
DR Pfam; PF00002; 7tm_2; 1.
DR Pfam; PF00028; Cadherin; 8.
DR Pfam; PF00008; EGF; 2.
DR Pfam; PF01825; GPS; 1.
DR Pfam; PF00053; Laminin_EGF; 1.
DR Pfam; PF02210; Laminin_G_2; 2.
DR PRINTS; PR00205; CADHERIN.
DR SMART; SM00112; CA; 9.
DR SMART; SM00181; EGF; 4.
DR SMART; SM00179; EGF_CA; 3.
DR SMART; SM00180; EGF_Lam; 2.
DR SMART; SM00303; GPS; 1.
DR SMART; SM00008; HormR; 1.
DR SMART; SM00282; LamG; 2.
DR SUPFAM; SSF49313; Cadherin-like; 9.
DR SUPFAM; SSF49899; Concanavalin A-like lectins/glucanases; 2.
DR SUPFAM; SSF57196; EGF/Laminin; 2.
DR PROSITE; PS00010; ASX_HYDROXYL; 1.
DR PROSITE; PS00232; CADHERIN_1; 5.
DR PROSITE; PS50268; CADHERIN_2; 9.
DR PROSITE; PS00022; EGF_1; 3.
DR PROSITE; PS50026; EGF_3; 3.
DR PROSITE; PS50227; G_PROTEIN_RECEP_F2_3; 1.
DR PROSITE; PS50261; G_PROTEIN_RECEP_F2_4; 1.
DR PROSITE; PS50221; GPS; 1.
DR PROSITE; PS50025; LAM_G_DOMAIN; 1.
PE 4: Predicted;
KW Calcium {ECO:0000256|ARBA:ARBA00022837, ECO:0000256|PROSITE-
KW ProRule:PRU00043}; Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157, ECO:0000256|PROSITE-
KW ProRule:PRU00076};
KW EGF-like domain {ECO:0000256|ARBA:ARBA00022536, ECO:0000256|PROSITE-
KW ProRule:PRU00076};
KW G-protein coupled receptor {ECO:0000256|ARBA:ARBA00023040};
KW Laminin EGF-like domain {ECO:0000256|ARBA:ARBA00023292};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Receptor {ECO:0000256|ARBA:ARBA00023170};
KW Reference proteome {ECO:0000313|Proteomes:UP000054783};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}; Signal {ECO:0000256|SAM:SignalP};
KW Transducer {ECO:0000256|ARBA:ARBA00023224};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..20
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 21..2667
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5006874178"
FT TRANSMEM 2292..2312
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 2370..2391
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 2411..2432
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 2444..2464
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 115..231
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 232..341
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 342..448
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 449..554
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 555..658
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 659..761
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 762..867
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 868..975
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 999..1099
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 1243..1279
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 1323..1531
FT /note="Laminin G"
FT /evidence="ECO:0000259|PROSITE:PS50025"
FT DOMAIN 1527..1563
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 1753..1788
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 1881..1956
FT /note="G-protein coupled receptors family 2 profile 1"
FT /evidence="ECO:0000259|PROSITE:PS50227"
FT DOMAIN 2286..2386
FT /note="G-protein coupled receptors family 2 profile 2"
FT /evidence="ECO:0000259|PROSITE:PS50261"
FT REGION 2576..2637
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2576..2597
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2605..2637
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT DISULFID 1269..1278
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 1553..1562
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 1778..1787
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
SQ SEQUENCE 2667 AA; 299122 MW; 08E0F94621A379CA CRC64;
MLAGVLCCSL LFQASLFSSA AVHPQSTLLR KVLYVNSTCI GAGGPVFPSF DRWLLKRFNV
PVTANSICLG EWFITTVDGE LSTGEEEGSV SAFSVQLKLR RRRRASRHRR AQSNDGDQWS
GFSKSRYEVS VLEEQDPPIS LLNFAQLSSA ANVETVSSCS VTGAGNVQSQ NLFTVEKETG
RLITTGRLDR EQADKHTLRI TCYEMTSNGR RSTTAIVLVN VLDLNDHEPV FERSNYAASI
SESVEPGTTV LHVHAQDEDA GRNGRIQYSV QRTNPETPLP FSLGSDDGVL RVEKPLDRET
CPFYRFEVLA CDQPLTITER LCAKALVEVT VDDENDNAPE FEQSSYVVEI DENLDPNDKP
VIANVMARDR DFGHNGEVKY SIVSGNAEGR FSIDYNTGEV RLVDRVDYRQ TDHYELVIRA
QDSAIFSLSN TTLLEIRIRD VNDHAPQFYA PVFQESVRED VPVGYRLLRL AAYDLDSGRN
SEIRFRFTGP EANNCPLEVD SVTGWVTVAK PLDHELEPTI ELQVEAVDLG NPPLASNAKL
IVNVLDVDDN VPVFPEKQLN VSVPETARRG SLLLRIAAHD PDNNSGRLQY SIISGNDDRA
FILLNEENNY CSLAVDQPLS YTSKPIHVLS IKVTDSAGHW DTMTVRVQVE DVNSAPTFAE
HSSTIHVRES EPVGSTVTVV RATDSDDGEN ARLQYQLEGG EPVFAIEPST GVLFVNGTLD
RESQSRFKLK VIATDHGQPP LSGSMDLEVV LDDVNDNAPV FSRTRYVTNV SEDAAVGVSL
LHLTATDSDY GINSRITYHF SDEDPENDAF QIDPSSGVVR VARPLDRERR AVYEITVLAK
DKGEPPLIGR TTLVINVDDV NDNAPKFDRE AYQFEVYENV PIGTIVGHVL AVDPDVGEHA
LVSYKILGGD DAAAFEIHSP MSKSEGMDLV TRIELDFESD RRTYQFHIQA SSGQLSSMAE
VLVRILDLND HEPVFDDFYL VVYNHESDSW NKDLSKRSIG RVPAFDLDLN DTLHYKIAAG
NEADLIQLDS NTGELRLSAA LNTNRRIRLL LLIQVSDGIN AVQATCTVIV EMITNSALLN
SVTFRISGLT MNSFLNPTAY GRLLDSLSAL IPSDRRDVLI FSVRQDNELH GEPTLNVSLV
LRKANSDRFL SGEELHELVD FNRKRLSEAS NLNILPLADE LCSREPCLNN ERCRNVLKFD
GTGDFIVTEN FIFKPVHCIS TFICECPIGF AELSKQRPGC NIEINLCYSS PCKAGGTCLS
RENGYSCICR PDFTGKNCEF PISNSYCIAD ICHGGSLCTL VQGKQKCQNC TYDADSTNEY
CELTTRTFQP NSFVEFPTLN QRNRFNITFQ FTTTVLDGML FYAGRQKAEN DFIVLELANG
RLKLSMSLGE SDIKVLNLDS DYTLNDGQWH KVQVIYFNRT VTLILDDCDP YLALNPNRIF
RYSQCAAHME LKLDEKCNDP MVPCYRFLDI TSPLYLGGLP SRNRHQRFRI MPVGFVGCMG
HLHIDHKMIN LNHYISNQMT VPGCAAMTKN CRRNPCQRNS ACQGIWEDYI CKCPTDYAGK
NCSDYVGKPI SLPTSSSSVS FKVPPHAEIP LVFGIQFRTA QTDADIVVVE LTSGKKIILQ
ITDQLASVTL ERKHQQLAQR LVSDSKWHSL LCEMQNDQII LNVDYVYQLT IPLSEKLNGI
VKKIKINISS SKNNNNHNHL SNPFTGCLKG AFVDKPMQNK KAYLQILHQK NIIKQCTLPD
NFCPKRDADG YCMNLCTLHP CLNGGTCNDQ WNSYVCQCVE NFTGRNCEHR LSTIGGRCPK
GWWGNSTCGP CNCDTTKGYD ANCDKYTGIC KCTDKTYFDD EKKQCTPCNC FYPAGALNMS
CNSETGQCHC RGNAVGKRCD ICADPRAQIS RISGYCEIVT NGCPENWMSD ILWPAMKSNR
TSTKPCPRGW QGRATRYCNE KGFWGKPRLE NCTTAEFQTL ENKIKDLQSN FKIDPITITA
VAEKLKNATQ RKSLYGHDLF AVGRILLKIL TLELSDQHAL PVAYQHDRNF ASNIIASLDE
AFSVNIRQNA GDADGQFLEQ TLELVNQFHD YGIKIAAYQQ KSHVDSMEYT GKSVVYAIQT
VDLKNSDFQR TATLGRSKKS VAIQLDIQPE EVKDLHKART LFYAVYENAY DAELQRLSPS
FAKCNVHNIH SPLLSVGVID NAGKQVISIE KPAFFTFPLP SWMKNNYLIP FCMFWNAKNT
YDDDDDESEP KWSTQGCYVD YFNRSHVICA CNHLSTFAVS MRDFMTTDTV LSYFALTVTT
LSMLKCSVIG NALLFVNVAL FTWLVVVPVE IFKTSTPLKQ TNNYHTWLRH MLIWSKEHTI
PTVYVAIRIL KDSFKATHEE CWLSFYDPTL IFFAAPVVVL MLLSLYASAM ALIFDCKHKQ
KLFPNGSKNR LYIFICFQLG IVAQWWFSYF AFNLTSYGLY YTYYGMSLVN MPLGAFLIFS
IIVINTQTSR KANQCNTKQT ADADLWLSMN VSQFEMSMKQ STVSDACCTE EPTEMDRLMI
TTVDGHEIHQ FSCEDMKLQN LNHDEKIYWK KAYAEQQPLD SSRVYLLEKV CNSENSQRYP
ENSWPKLPTQ TQGYNSPRGR PVALITGTNR SQMDGLPSRR PSIGRSPTSP SSGQISPAIL
SSPIKVLQYG TSAHSSPVLE IGEKLDR
//
