ID   A0A0V1A3V7_9BILA        Unreviewed;       935 AA.
AC   A0A0V1A3V7;
DT   16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT   16-MAR-2016, sequence version 1.
DT   27-MAR-2024, entry version 21.
DE   SubName: Full=Pyruvate dehydrogenase phosphatase regulatory subunit, mitochondrial {ECO:0000313|EMBL:KRY19536.1};
GN   Name=PDPR {ECO:0000313|EMBL:KRY19536.1};
GN   ORFNames=T12_15042 {ECO:0000313|EMBL:KRY19536.1};
OS   Trichinella patagoniensis.
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Enoplea; Dorylaimia;
OC   Trichinellida; Trichinellidae; Trichinella.
OX   NCBI_TaxID=990121 {ECO:0000313|EMBL:KRY19536.1, ECO:0000313|Proteomes:UP000054783};
RN   [1] {ECO:0000313|EMBL:KRY19536.1, ECO:0000313|Proteomes:UP000054783}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ISS2496 {ECO:0000313|EMBL:KRY19536.1};
RA   Korhonen P.K., Edoardo P., Giuseppe L.R., Gasser R.B.;
RT   "Evolution of Trichinella species and genotypes.";
RL   Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the GcvT family.
CC       {ECO:0000256|ARBA:ARBA00008609}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KRY19536.1}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; JYDQ01000034; KRY19536.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A0V1A3V7; -.
DR   STRING; 990121.A0A0V1A3V7; -.
DR   Proteomes; UP000054783; Unassembled WGS sequence.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR   Gene3D; 2.40.30.110; Aminomethyltransferase beta-barrel domains; 1.
DR   Gene3D; 3.30.70.1400; Aminomethyltransferase beta-barrel domains; 1.
DR   Gene3D; 3.30.9.10; D-Amino Acid Oxidase, subunit A, domain 2; 1.
DR   Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 1.
DR   InterPro; IPR006076; FAD-dep_OxRdtase.
DR   InterPro; IPR036188; FAD/NAD-bd_sf.
DR   InterPro; IPR032503; FAO_M.
DR   InterPro; IPR028896; GCST/YgfZ/DmdA.
DR   InterPro; IPR013977; GCV_T_C.
DR   InterPro; IPR006222; GCV_T_N.
DR   InterPro; IPR029043; GcvT/YgfZ_C.
DR   InterPro; IPR027266; TrmE/GcvT_dom1.
DR   PANTHER; PTHR43757; AMINOMETHYLTRANSFERASE; 1.
DR   PANTHER; PTHR43757:SF9; SARCOSINE DEHYDROGENASE; 1.
DR   Pfam; PF01266; DAO; 1.
DR   Pfam; PF16350; FAO_M; 1.
DR   Pfam; PF01571; GCV_T; 1.
DR   Pfam; PF08669; GCV_T_C; 1.
DR   SUPFAM; SSF101790; Aminomethyltransferase beta-barrel domain; 1.
DR   SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
DR   SUPFAM; SSF103025; Folate-binding domain; 1.
PE   3: Inferred from homology;
KW   Pyruvate {ECO:0000313|EMBL:KRY19536.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000054783}.
FT   DOMAIN          65..445
FT                   /note="FAD dependent oxidoreductase"
FT                   /evidence="ECO:0000259|Pfam:PF01266"
FT   DOMAIN          450..503
FT                   /note="FAD dependent oxidoreductase central"
FT                   /evidence="ECO:0000259|Pfam:PF16350"
FT   DOMAIN          505..800
FT                   /note="Aminomethyltransferase folate-binding"
FT                   /evidence="ECO:0000259|Pfam:PF01571"
FT   DOMAIN          839..913
FT                   /note="Glycine cleavage T-protein C-terminal barrel"
FT                   /evidence="ECO:0000259|Pfam:PF08669"
SQ   SEQUENCE   935 AA;  105828 MW;  217ADB429C39514B CRC64;
     MLSLHYLRAA NSKFMLMVKN AYSPRLCFRQ FTSGLSVNEL NLSMSDLPFR SYEYEDLIEF
     PEKVDVLICG GGLSGLCLAY HLSAIGKHKI LLLERNRLSK CATMLSTGLL LANQTWRSHG
     MLDLVHFADD FYNYLSKQQD IAGYSEWSRM LVASTEATAL QLKRILSIAK ASNFNGRFLS
     PEELKKLDKE CQIGETKAIN IESEAALLLD DVRVNQYASA HVLASMINRT GVDIVENCAV
     RFVKMDNQCR VVGAETDYGF VECDAFVDAA GAFSGGFFGH DVDPAIKQFP LHPLFYNSVV
     LEAEGIYTFP STVVHDVDLN VYVSHSGRYL ICGGFDKHAF KLDNEDSLLL YGAEGSQLPE
     QWDFFGLRFC FFFTAVHVLE KLAKRFPALL NLPVARQFVI GEAFTPDGLP VVGALPSVPN
     YYCLTGMNGL VTTMAPGLSK VLAQRICGIE PELDVDKFDV CRFILLHCNK HYISQRATEV
     AGSVFSNFNP LYEWSSVRRL RLSPLHEELK EAGGVFGEVM GFEQVLYFSK GDVPWMKCGE
     SFPLGKPEWF DHVAVEYRAC REKVAIMEMS YLSKFEVKGQ DYGVIYFLQK MCSANVDQPI
     GSAIFTGIQN YKGGYVADCT LNRFGQYEFF MTAAPDQQTR LRIWMQRHLT AEDQTSIHDV
     TSKYTTLCIL GPASRMLMQE LTDEPLSSFA SFSCRVRRSV IYSNAQITLM DLFLLFQKIN
     IGCVSGIRAV SVTHCGELGW TLHCPNEFAQ YIFEQLRTYG QSYDVQLAGN YAFNSLRIEK
     FYVRWGVDID WMTTPNECGR SFRVDFNKDF IGKDALLEEM QMCPRRLFVQ LLFLGHDMRR
     DPWPFGNEPI YRNGDFCGFT TSTAYAFTIG CQVSLGYINI NGMRTADEAA DYVLDKYAVY
     EIEIAGKRYQ VQLNLHSPDL PMVSSEHPFH YRPTQ
//