ID A0A0V1A7T2_9BILA Unreviewed; 1008 AA.
AC A0A0V1A7T2;
DT 16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT 16-MAR-2016, sequence version 1.
DT 27-MAR-2024, entry version 16.
DE SubName: Full=Twinkle protein, mitochondrial {ECO:0000313|EMBL:KRY20542.1};
GN Name=PEO1 {ECO:0000313|EMBL:KRY20542.1};
GN ORFNames=T12_16016 {ECO:0000313|EMBL:KRY20542.1};
OS Trichinella patagoniensis.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Enoplea; Dorylaimia;
OC Trichinellida; Trichinellidae; Trichinella.
OX NCBI_TaxID=990121 {ECO:0000313|EMBL:KRY20542.1, ECO:0000313|Proteomes:UP000054783};
RN [1] {ECO:0000313|EMBL:KRY20542.1, ECO:0000313|Proteomes:UP000054783}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ISS2496 {ECO:0000313|EMBL:KRY20542.1};
RA Korhonen P.K., Edoardo P., Giuseppe L.R., Gasser R.B.;
RT "Evolution of Trichinella species and genotypes.";
RL Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KRY20542.1}.
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DR EMBL; JYDQ01000024; KRY20542.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0V1A7T2; -.
DR STRING; 990121.A0A0V1A7T2; -.
DR Proteomes; UP000054783; Unassembled WGS sequence.
DR GO; GO:0043139; F:5'-3' DNA helicase activity; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0016787; F:hydrolase activity; IEA:InterPro.
DR GO; GO:0003697; F:single-stranded DNA binding; IEA:InterPro.
DR GO; GO:0006260; P:DNA replication; IEA:InterPro.
DR CDD; cd01122; Twinkle_C; 1.
DR Gene3D; 3.40.50.1820; alpha/beta hydrolase; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR029058; AB_hydrolase.
DR InterPro; IPR013094; AB_hydrolase_3.
DR InterPro; IPR007694; DNA_helicase_DnaB-like_C.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR027032; Twinkle-like.
DR PANTHER; PTHR12873; T7-LIKE MITOCHONDRIAL DNA HELICASE; 1.
DR PANTHER; PTHR12873:SF0; TWINKLE MTDNA HELICASE; 1.
DR Pfam; PF07859; Abhydrolase_3; 2.
DR Pfam; PF03796; DnaB_C; 1.
DR SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51199; SF4_HELICASE; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000054783}.
FT DOMAIN 337..544
FT /note="SF4 helicase"
FT /evidence="ECO:0000259|PROSITE:PS51199"
SQ SEQUENCE 1008 AA; 114620 MW; 77156069D80C9930 CRC64;
MHVKNRAAYL PVNHFVNKPF AMAKHDRPWK CAKRSVIFSS TANSPYNNES FSEKINKVRV
SLVQACIANI NKVDTMMNGY SGSSDEEAAS DSPKTVVHTV WNQSIPINQM SLPKLTRLRQ
LLSLRHIQDS TFAKYNVRAT ANGDGLIFPR YTDRVERVGV RQLKPSGLKI FRLTENRNQP
GIIEETIPDS STYVGFFGYH LVKSVDVETV LLFNEADALS VHQAAGKVAL AVHDQYGPFQ
NQLLSLLTEL IHVIIWPPPE KYNRGKLLAK SLTSTNCHLI SPASCKNMRA ADALALPGKG
RQLITGVIKA CERVEEKSLS TFDKLKELTK EYYYGYGSVS GICKWSRFSA LNNYLKGFRL
GELTLIGGGS ACGKKTFLAE YALDICCQNV PTLWCCLELP VGRLTATLVE QFSKDAFFEE
NTNQRSFDYW YEEISRLPMY FAKFDKVGFT KLKDIVEVID RLAASKEVQH IVIDDVTALQ
EWTLAKNGYD LNLIFSDLRR LAQNRNCHIT GSMLLSKFQN SKENNNADTL QQNAVNMQAM
KEADNVLVIC TKKLAQDITD VEHENFLQIW KTRRGGDLVL SNYIEMNFNR MTKCYTLTVG
DRALPEGTWR LCILPLVLVA VISIVVNQLY VPLPDRFAER EKMQVIETVA RVLYMYPGKW
LELFSTKWQL CWTRLVLNSL AWLCSYAYRS TEPQNVHIHT IMLDDVAARV YIPDKVDTDA
AIVYIHGGGF VLLNVDSYDL ITRHLAKLTN MITVSIEYRL APEHKFPAAI DDCERAIVYF
LRHAHKLYSI NSDKVVLVGD SAGGNLAAVV TQRLLLIYPV VQFVDFMTPS YQMAYRLYGR
TALPDPESIV RWMLVYLGLD VEHVPKVLRS DHVDPIRQLQ LLQAVQHDQL PPEFLDPSYY
KKPPPKLNNT ESSEAMHQVQ SYLLDWQVSP LLQQDMSDLP KALVLTCEFD PLRDEGYFYV
HRLRQAGVNA SWIHYNTGFH AMLNIHNEVP LGRQAIQDVA TFIRHNLS
//
