ID A0A0V1AC47_9BILA Unreviewed; 2152 AA.
AC A0A0V1AC47;
DT 16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT 16-MAR-2016, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:KRY22395.1};
GN Name=K03H1.5 {ECO:0000313|EMBL:KRY22395.1};
GN ORFNames=T12_2456 {ECO:0000313|EMBL:KRY22395.1};
OS Trichinella patagoniensis.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Enoplea; Dorylaimia;
OC Trichinellida; Trichinellidae; Trichinella.
OX NCBI_TaxID=990121 {ECO:0000313|EMBL:KRY22395.1, ECO:0000313|Proteomes:UP000054783};
RN [1] {ECO:0000313|EMBL:KRY22395.1, ECO:0000313|Proteomes:UP000054783}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ISS2496 {ECO:0000313|EMBL:KRY22395.1};
RA Korhonen P.K., Edoardo P., Giuseppe L.R., Gasser R.B.;
RT "Evolution of Trichinella species and genotypes.";
RL Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00302}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KRY22395.1}.
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DR EMBL; JYDQ01000009; KRY22395.1; -; Genomic_DNA.
DR Proteomes; UP000054783; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015377; F:chloride:monoatomic cation symporter activity; IEA:InterPro.
DR GO; GO:0007160; P:cell-matrix adhesion; IEA:InterPro.
DR CDD; cd00033; CCP; 1.
DR Gene3D; 1.20.1740.10; Amino acid/polyamine transporter I; 1.
DR Gene3D; 2.10.70.10; Complement Module, domain 1; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR InterPro; IPR004841; AA-permease/SLC12A_dom.
DR InterPro; IPR005533; AMOP_dom.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR014756; Ig_E-set.
DR InterPro; IPR003886; NIDO_dom.
DR InterPro; IPR018491; SLC12_C.
DR InterPro; IPR004842; SLC12A_fam.
DR InterPro; IPR035976; Sushi/SCR/CCP_sf.
DR InterPro; IPR000436; Sushi_SCR_CCP_dom.
DR InterPro; IPR001846; VWF_type-D.
DR PANTHER; PTHR11827:SF53; K+_CL-COTRANSPORTER; 1.
DR PANTHER; PTHR11827; SOLUTE CARRIER FAMILY 12, CATION COTRANSPORTERS; 1.
DR Pfam; PF00324; AA_permease; 2.
DR Pfam; PF03782; AMOP; 1.
DR Pfam; PF06119; NIDO; 1.
DR Pfam; PF03522; SLC12; 1.
DR Pfam; PF00094; VWD; 1.
DR SMART; SM00723; AMOP; 1.
DR SMART; SM00032; CCP; 1.
DR SMART; SM00539; NIDO; 1.
DR SMART; SM00216; VWD; 1.
DR SUPFAM; SSF57535; Complement control module/SCR domain; 1.
DR SUPFAM; SSF81296; E set domains; 1.
DR PROSITE; PS50856; AMOP; 1.
DR PROSITE; PS51220; NIDO; 1.
DR PROSITE; PS50923; SUSHI; 1.
DR PROSITE; PS51233; VWFD; 1.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157, ECO:0000256|PROSITE-
KW ProRule:PRU00302};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000054783};
KW Sushi {ECO:0000256|PROSITE-ProRule:PRU00302};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 1120..1142
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1243..1264
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1276..1301
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1322..1343
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1375..1396
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1403..1422
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1534..1555
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1567..1587
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1619..1641
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1671..1688
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1694..1715
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1727..1745
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 174..338
FT /note="NIDO"
FT /evidence="ECO:0000259|PROSITE:PS51220"
FT DOMAIN 573..728
FT /note="AMOP"
FT /evidence="ECO:0000259|PROSITE:PS50856"
FT DOMAIN 740..948
FT /note="VWFD"
FT /evidence="ECO:0000259|PROSITE:PS51233"
FT DOMAIN 1052..1111
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT REGION 2034..2067
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2034..2058
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT DISULFID 1082..1109
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00302"
SQ SEQUENCE 2152 AA; 243927 MW; 26C983BCB4466F2C CRC64;
MVIRRMKLFE LSGFPNGIIV HLIKVLIMSK ERSDDEDAQV NLPLSQEWKN LYQYGKEMHD
AVLVDRPNHE TQIDLDFFFP YYGFRFNYTF ISPNGFISFG RSKWIQPPYT FPNPKWPERQ
DPSFIAPFLS RATFQYTGST RISNVWYRTV HRTVASSGDE VNFYSKKSQN QDVNFLHSQT
EKPKYRRIHS GYVEDDQLLD SLTSDLQDGV NGANGFRALH ALIVTWERMA FGGAPKIVNL
QDYENAKCWQ NTFQLVLLTD EIRSYTIFNY ATLNWTSSTD AGSLRGRGGY QSAIAGFNGG
NGTGFTAMPY SARGEIFKLA TFSSVSIPGR WMYRVDEEII RGGCSNASSG YLVIAPDRGT
MLGGIAVNVT GQCLMPRNTV HVLFDELVVI CSRLSIHRAQ CVLPKFHRVG LVSVKISSDG
GRTYPYIGIF YFVPPDRAVP GVVLRRDVLN YQLNAFDNPT PDLLSITWSA KNLTNIPNAK
VTIDLFGYWE NAEMHKFERV GIIAENVNNV GFYEFSPKKL SRPKDPALLD KWKNYDFGVV
RVSVKDRTDL GVLYSMLTSF SWYFLPDWEK NLGPDWALKR CIEWYEKDGK WRNFWMDLQP
CPCTLDQALF DVGRFMPYLE CDMNGDGGCY YHRGSSHCVM STHAAWSGGQ TVCCYDFDGW
LLHSDDFEDL DVLRYYSPGL PYRAHMFGSY PYQLPPYIPS LSNWFHDLAP YHMCCRFADK
CSFLFWRRQT RSCQGYIPPA AGFAYGGVHF ITFDGVKYRF NGKGYYLLVK SDHPQHKLTI
QIRLEQPPKT RWDVYPNSTI ITGVALREND SDVVQILARK EFRRWRYKTD VFIRGILRHF
DTFDTKVQQF KGLNVWSPAR NFDQSEMHIQ LLSGAGVVVR EKSGMLDVTV TLPNSFIQSS
AVRKVRYSTY GLLGVYNENA DDDLQPPNTR HVPVSGKQCY VLPDASTVYY EFGKVDGSNA
FIGPVLFNDF SQPLNNPLLF SQSNYRPSFD DLEIRGKAAL EIRNDDIQRA CQNNVPCKQM
FVSTGVKTWA IYTKSAEEQF LSIQASGSKK WLSCGPLWKA VGAVKMPPGN NYLSGVTVTF
SCRPEYFLHG TIQRSCVNGT WTPGWHVWCR TKSEEYALKW TTGILSTLLF LMFFFSIFYY
CYRVHWLPKY RQRMAGNKCQ TDQTKLPKVL QNHSIPLKIK YLIDNMDSSN TNSNRDETTT
VGKVTDIMNV CKSSQNSRCV PLGEYVQKNE ALLENRLKKS AKLGTMLGVF LPTIQNIFGV
IMFIRLHWIV GMAGLIQSLI IVSMCSFLTF LTSISLSAIA TNGVFEEGGP YFVISRNLSP
EFGASIGILF FLANAVATAM YVVGHVEVFL TYVAQDLPQF GTALLRTDEE MANNFRIYGT
ILLLIIVGIA ACGVKVTQTF APISLFCVII SIIGVFTGSF VYNNTDSDRI CMVGEKAIKR
LPLIVNGTID SSCTKEENGT LWNLYCNVNS SGNGTTCDPY FLNHNVTLRI VRHGMLSQHY
KNNLHSYYMK AGEAAPGEKG LSGVEVTQDI TSTFYTLLAI YFPAVTGIMT GCNLSGDLAD
PQHSIPVGTI AAQLTTSFVF ISYTLFYGTA IDRALLMDKY GESLGGSLVS GQLSWPTEWL
VIVGCLASTF GAGLQSLFSA ARLIQAVAKD NLVAKLQSFG KVTSKNEPCR ALLLSAFIAE
LTILIGAVDH IAPIVDFFFL ICYCFINIAC TLQTLLKMPN WRPRFKYYHW TLSLLGAILG
FFIMFSTHFD YAVIVLVMCL CIYKYVEYHG EKKEWGHGTE GFRFTTAHYV LAKLEDKDMH
PKNWRPHVLL FIKPDKTKEQ IMNDPALLFA AALEEGGGFL MLTTFIEMKE ENDSTNQLIS
AETAKLKDVL KTMKIKAYVR VIPCNDIGEA VWIHTLGAGI GGLRPNIIIT DWPHRLKTWK
MTNVKYWDFL YSLFYRCTAS KSLIIPKGHI PSLNEILSGN IDVWWLAHDG GMQVMLTVLL
KTVHDQLKKW VYNLRIDAKV QVVEMPLFKY DQNDEVKNFL STRRKLAAEL GLEEGDEKKA
NEETDQVLDT KDAENQGSES SEESTISFDE AIKDENVTWK TIEKRFLLSV YLNELMRRES
GESRLLIINL PEPPSNKQFM PIYLDYVDTL TTKLKAVILV RGTQKDVITI FS
//
