ID   A0A0V1AET7_9BILA        Unreviewed;       532 AA.
AC   A0A0V1AET7;
DT   16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT   16-MAR-2016, sequence version 1.
DT   27-MAR-2024, entry version 27.
DE   SubName: Full=Protein wntless-like protein {ECO:0000313|EMBL:KRY22755.1};
DE   Flags: Fragment;
GN   Name=Wls {ECO:0000313|EMBL:KRY22755.1};
GN   ORFNames=T12_5507 {ECO:0000313|EMBL:KRY22755.1};
OS   Trichinella patagoniensis.
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Enoplea; Dorylaimia;
OC   Trichinellida; Trichinellidae; Trichinella.
OX   NCBI_TaxID=990121 {ECO:0000313|EMBL:KRY22755.1, ECO:0000313|Proteomes:UP000054783};
RN   [1] {ECO:0000313|EMBL:KRY22755.1, ECO:0000313|Proteomes:UP000054783}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ISS2496 {ECO:0000313|EMBL:KRY22755.1};
RA   Korhonen P.K., Edoardo P., Giuseppe L.R., Gasser R.B.;
RT   "Evolution of Trichinella species and genotypes.";
RL   Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Endosome membrane
CC       {ECO:0000256|ARBA:ARBA00004337}; Multi-pass membrane protein
CC       {ECO:0000256|ARBA:ARBA00004337}. Golgi apparatus membrane
CC       {ECO:0000256|ARBA:ARBA00004653}; Multi-pass membrane protein
CC       {ECO:0000256|ARBA:ARBA00004653}. Membrane
CC       {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC       {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the wntless family.
CC       {ECO:0000256|ARBA:ARBA00008148}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KRY22755.1}.
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DR   EMBL; JYDQ01000007; KRY22755.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A0V1AET7; -.
DR   Proteomes; UP000054783; Unassembled WGS sequence.
DR   GO; GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0017147; F:Wnt-protein binding; IEA:InterPro.
DR   GO; GO:0016055; P:Wnt signaling pathway; IEA:UniProtKB-KW.
DR   InterPro; IPR047843; WLS-like_TM.
DR   InterPro; IPR009551; Wntless.
DR   PANTHER; PTHR13449; INTEGRAL MEMBRANE PROTEIN GPR177; 1.
DR   PANTHER; PTHR13449:SF2; PROTEIN WNTLESS HOMOLOG; 1.
DR   Pfam; PF06664; MIG-14_Wnt-bd; 2.
PE   3: Inferred from homology;
KW   Developmental protein {ECO:0000256|ARBA:ARBA00022473};
KW   Golgi apparatus {ECO:0000256|ARBA:ARBA00023034};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000054783};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius};
KW   Wnt signaling pathway {ECO:0000256|ARBA:ARBA00022687}.
FT   TRANSMEM        24..46
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        254..274
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        294..316
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        371..398
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        419..447
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        467..490
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          198..318
FT                   /note="Wntless-like transmembrane"
FT                   /evidence="ECO:0000259|Pfam:PF06664"
FT   DOMAIN          318..494
FT                   /note="Wntless-like transmembrane"
FT                   /evidence="ECO:0000259|Pfam:PF06664"
FT   NON_TER         1
FT                   /evidence="ECO:0000313|EMBL:KRY22755.1"
SQ   SEQUENCE   532 AA;  61440 MW;  44580D03E2A2805D CRC64;
     LPCMKCTGME NIGAVIENLS SKKLYILFTI LGIVQVIFFL VGGLLAPSPS SHMEHLMRIC
     VDRSLGQDNR WFYIRPKDGC PEELNDLGTI ENPYLLATGD PRELVFVAQM PNPRNDIQLE
     FSRWFQWLLG LLVVQTEYSQ NPQWKMGTNP ELRLEVRMGY KTHDDPVHVW HELTSATISR
     RLRCTIEDYH MQNGFNYQCE PIELFELGSC DYPFYLLNIR IPGGNESAHY NTEIGRLTEM
     SVMEIHQNGG FTKVWLSMKT VLFPIMLAGL VWYYRRVRGL PRPPVLLEKS IFCLGAAMLF
     IDFPIEWLSF WVRLPFMLDQ ETKNDLSAYW KNLSSVFFGC ACLLVFDACE RGVHLTSPFY
     SIWSTSLGSN LAYLFIILAV ISAIVYFIFL FCLVTRVWRT IKQRRASMNT MKRPRRLRFQ
     AIIFRFKFLM FFTLLCAAMT VIAFALTQIG EGQLRWGDYD EYESIQYTSA VQTGVYGMWN
     IYTFCLLAMY APSHKKYVES TQALNNEDDD DDQGLAATEM SSLTAFAKPA FD
//