ID   A0A0V1B462_TRISP        Unreviewed;       830 AA.
AC   A0A0V1B462;
DT   16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT   16-MAR-2016, sequence version 1.
DT   27-MAR-2024, entry version 16.
DE   SubName: Full=Patched domain-containing protein 3 {ECO:0000313|EMBL:KRY31738.1};
GN   Name=Ptchd3 {ECO:0000313|EMBL:KRY31738.1};
GN   ORFNames=T01_10514 {ECO:0000313|EMBL:KRY31738.1};
OS   Trichinella spiralis (Trichina worm).
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Enoplea; Dorylaimia;
OC   Trichinellida; Trichinellidae; Trichinella.
OX   NCBI_TaxID=6334 {ECO:0000313|EMBL:KRY31738.1, ECO:0000313|Proteomes:UP000054776};
RN   [1] {ECO:0000313|EMBL:KRY31738.1, ECO:0000313|Proteomes:UP000054776}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ISS3 {ECO:0000313|EMBL:KRY31738.1};
RA   Korhonen P.K., Edoardo P., Giuseppe L.R., Gasser R.B.;
RT   "Evolution of Trichinella species and genotypes.";
RL   Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the patched family.
CC       {ECO:0000256|ARBA:ARBA00005585}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KRY31738.1}.
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DR   EMBL; JYDH01000112; KRY31738.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A0V1B462; -.
DR   InParanoid; A0A0V1B462; -.
DR   Proteomes; UP000054776; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   Gene3D; 1.20.1640.10; Multidrug efflux transporter AcrB transmembrane domain; 2.
DR   InterPro; IPR003392; Ptc/Disp.
DR   InterPro; IPR000731; SSD.
DR   PANTHER; PTHR10796; PATCHED-RELATED; 1.
DR   PANTHER; PTHR10796:SF92; PATCHED-RELATED, ISOFORM A; 1.
DR   Pfam; PF02460; Patched; 1.
DR   SUPFAM; SSF82866; Multidrug efflux transporter AcrB transmembrane domain; 2.
DR   PROSITE; PS50156; SSD; 1.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000054776};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        33..53
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        182..202
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        273..292
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        299..320
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        326..349
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        370..390
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        410..427
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        467..486
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        665..684
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        691..713
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        754..777
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        789..816
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          298..423
FT                   /note="SSD"
FT                   /evidence="ECO:0000259|PROSITE:PS50156"
SQ   SEQUENCE   830 AA;  94511 MW;  DB873F8EEB49AD0C CRC64;
     MRWFGRQPVS STVDRLLDQL YDHYGILVSQ RPWHFLVASL ITTALLSIGL SCFTSYNDIR
     LLYTPLDSLS LSERKVDDQF WAWKAPNKNS TIFDDAEENP DRTVALFILL RAEQRQTNIF
     DRNLCEAIEQ INEDIQALND SSFEQFRYNS DGNSAYNHAG RMLCKLYFNP TLRRSPNVRF
     RYPYLTAFGF QLYLGFTIAG IHEHVNGTLS GFESFSLGYS WLTKRGTFDE FSSLMRSVDL
     SIQPHAKQAN LTYVIYSDEL ANQEVNKNAT YTFPYLAVSA IAVLIFCTLS NWGKSVEALL
     GCLSSLLAVL SSFGLLAYAS VPFNSIVVVT PFLALAIGID DTFIAINAWR RTDPKLSVEE
     RFRLSIRESG SAITVTSLTD VALFCIGTLS NTPAIRVFSQ YTATAMAFDF FYQLTFVAPA
     IVLGGRLEQK KRHDQNYPHQ VQALPARLFK NYYAPLLNSR LIQTPAMLLY VLYILIAFWG
     CCHIRVNMSI SMLLVDESPL RAFFDLKDEY LRSSVAVTVH VRRPPDLHDD RQLSEFWSMV
     SKMEQMPQSR GPMSSFLWLR DYMMYIQNDR NLSHPLDALD TFLNSYQYRA YANTVRWYKD
     VQTGETVLNR FLFQTYYATN GQWEEVTALV NSLRTVAQHY QQFNVTIFIG ESFVWDQFVS
     IPDNTIQTVG VGVLCMLAMS ALFIPHMHSV FWIGLTLLSM DLGVIGGLSL WGVTLDPVSM
     INIIMSLDFP VEYAAHVCHC FYRMPDHWSN ERKLVELLGN VAWPLLQGGT AALLATLPLG
     FVPSYVIRVF FRTVVLILSI GMLHALVWLP LFLVLLTPKS KVDQKSISCN
//