ID A0A0V1BCL8_TRISP Unreviewed; 320 AA.
AC A0A0V1BCL8;
DT 16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT 16-MAR-2016, sequence version 1.
DT 24-JAN-2024, entry version 23.
DE RecName: Full=cathepsin X {ECO:0000256|ARBA:ARBA00012516};
DE EC=3.4.18.1 {ECO:0000256|ARBA:ARBA00012516};
DE Flags: Fragment;
GN Name=Ctsz {ECO:0000313|EMBL:KRY34679.1};
GN ORFNames=T01_8674 {ECO:0000313|EMBL:KRY34679.1};
OS Trichinella spiralis (Trichina worm).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Enoplea; Dorylaimia;
OC Trichinellida; Trichinellidae; Trichinella.
OX NCBI_TaxID=6334 {ECO:0000313|EMBL:KRY34679.1, ECO:0000313|Proteomes:UP000054776};
RN [1] {ECO:0000313|EMBL:KRY34679.1, ECO:0000313|Proteomes:UP000054776}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ISS3 {ECO:0000313|EMBL:KRY34679.1};
RA Korhonen P.K., Edoardo P., Giuseppe L.R., Gasser R.B.;
RT "Evolution of Trichinella species and genotypes.";
RL Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=Release of C-terminal amino acid residues with broad
CC specificity, but lacks action on C-terminal proline. Shows weak
CC endopeptidase activity.; EC=3.4.18.1;
CC Evidence={ECO:0000256|ARBA:ARBA00001594};
CC -!- SIMILARITY: Belongs to the peptidase C1 family.
CC {ECO:0000256|ARBA:ARBA00008455}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KRY34679.1}.
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DR EMBL; JYDH01000063; KRY34679.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0V1BCL8; -.
DR SMR; A0A0V1BCL8; -.
DR STRING; 6334.A0A0V1BCL8; -.
DR eggNOG; KOG1543; Eukaryota.
DR InParanoid; A0A0V1BCL8; -.
DR Proteomes; UP000054776; Unassembled WGS sequence.
DR GO; GO:0008234; F:cysteine-type peptidase activity; IEA:InterPro.
DR GO; GO:0006508; P:proteolysis; IEA:InterPro.
DR CDD; cd02698; Peptidase_C1A_CathepsinX; 1.
DR Gene3D; 3.90.70.10; Cysteine proteinases; 1.
DR InterPro; IPR033157; CTSZ.
DR InterPro; IPR038765; Papain-like_cys_pep_sf.
DR InterPro; IPR013128; Peptidase_C1A.
DR InterPro; IPR000668; Peptidase_C1A_C.
DR PANTHER; PTHR12411:SF929; CATHEPSIN Z; 1.
DR PANTHER; PTHR12411; CYSTEINE PROTEASE FAMILY C1-RELATED; 1.
DR Pfam; PF00112; Peptidase_C1; 1.
DR PRINTS; PR00705; PAPAIN.
DR SMART; SM00645; Pept_C1; 1.
DR SUPFAM; SSF54001; Cysteine proteinases; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000054776}.
FT DOMAIN 81..311
FT /note="Peptidase C1A papain C-terminal"
FT /evidence="ECO:0000259|SMART:SM00645"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:KRY34679.1"
SQ SEQUENCE 320 AA; 36209 MW; 39AE35D0DFAD85D9 CRC64;
LNWKRENLNA TMRTSSTLLL LFFNLFFHYT APTKVEVKNA FTKNNVRHGH RSCYRPIFSN
EPNMVKTRLR PHEYPGVVEN LPKELNWCNY NGINFCSPTR NQHIPQYCGS CWAMGATSAL
ADRINIRRKG QWPMAYLSVQ HVIDCGNAGS CHGGNHLPVY AFAHKHGIVD ESCNNYQAKD
GVCDKFNECG NCVTFGQCYP VTNYTLYKVG DYGPLSGRVE MMAEIYKNGP IACGIAVTDS
FEAYTGGIYA EHKLLPIVNH IISVVGWGVD EESGIQYWIG RNSWEHGFFR IVTSEFKNNT
GRHYNLAIET MCAYADPVTF
//
