ID A0A0V1BEX0_TRISP Unreviewed; 1405 AA.
AC A0A0V1BEX0;
DT 16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT 16-MAR-2016, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE SubName: Full=Nephrin {ECO:0000313|EMBL:KRY35441.1};
DE Flags: Fragment;
GN Name=Nphs1 {ECO:0000313|EMBL:KRY35441.1};
GN ORFNames=T01_2375 {ECO:0000313|EMBL:KRY35441.1};
OS Trichinella spiralis (Trichina worm).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Enoplea; Dorylaimia;
OC Trichinellida; Trichinellidae; Trichinella.
OX NCBI_TaxID=6334 {ECO:0000313|EMBL:KRY35441.1, ECO:0000313|Proteomes:UP000054776};
RN [1] {ECO:0000313|EMBL:KRY35441.1, ECO:0000313|Proteomes:UP000054776}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ISS3 {ECO:0000313|EMBL:KRY35441.1};
RA Korhonen P.K., Edoardo P., Giuseppe L.R., Gasser R.B.;
RT "Evolution of Trichinella species and genotypes.";
RL Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KRY35441.1}.
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DR EMBL; JYDH01000054; KRY35441.1; -; Genomic_DNA.
DR Proteomes; UP000054776; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProt.
DR CDD; cd00063; FN3; 1.
DR CDD; cd00096; Ig; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 10.
DR InterPro; IPR013162; CD80_C2-set.
DR InterPro; IPR003961; FN3_dom.
DR InterPro; IPR036116; FN3_sf.
DR InterPro; IPR007110; Ig-like_dom.
DR InterPro; IPR036179; Ig-like_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR003006; Ig/MHC_CS.
DR InterPro; IPR013098; Ig_I-set.
DR InterPro; IPR003599; Ig_sub.
DR InterPro; IPR003598; Ig_sub2.
DR PANTHER; PTHR45889; IG-LIKE DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR45889:SF8; IG-LIKE DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF08205; C2-set_2; 3.
DR Pfam; PF00041; fn3; 1.
DR Pfam; PF07679; I-set; 3.
DR Pfam; PF13927; Ig_3; 3.
DR SMART; SM00060; FN3; 1.
DR SMART; SM00409; IG; 9.
DR SMART; SM00408; IGc2; 9.
DR SUPFAM; SSF49265; Fibronectin type III; 1.
DR SUPFAM; SSF48726; Immunoglobulin; 9.
DR PROSITE; PS50853; FN3; 1.
DR PROSITE; PS50835; IG_LIKE; 9.
DR PROSITE; PS00290; IG_MHC; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000054776};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 29..49
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1093..1118
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 70..163
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 174..278
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 283..374
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 379..479
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 484..577
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 582..676
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 683..775
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 780..856
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 873..982
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 986..1078
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:KRY35441.1"
SQ SEQUENCE 1405 AA; 154896 MW; AA40150917C36F2A CRC64;
LRCHVDVERQ LHEAFQSSLP IALLNLPDLT TYVLFHFNLL SISIMAIFVW SRQLVATVII
IYASLVATQK QYFKVPPNNV TVIEGQTAVL QCIISNQQGH TQWTKGGTFL GIDYNLYGYD
RYRIVGSRSS GEYNLEISQA KLEDDGEFEC QVSPGSEDGK GLRAVGSLNV LIPPKIITLD
PEKDGGKVES RSGRTVEVHC RAVGSKPKSE IRWYKNDKLI QDSNVFEESV QEKDKLITTV
SRIRWVAQPE DDGAIFTCSA RHPALLADDA LRTNFTLSVL YPPSFPEIRG YDGRTLKAGE
KLRLECEVTN GNPPPEVFWY RNDKIIDRTY VTHSTSSTND YDFIVDGSDH EAVYACHASN
PAVVTPLTSN VRLNVFYPPS KVHVIGPELS KIGDTVSFSC ISGSSNPPAK IYWVIDGKPI
KESVSSIRPS SDGKGFFSVS NISVQITNEK RDVQIVCSVV NEEILPSEGG RLTSSKKITV
LYPPESVSIF GYDGTPVVAG NIQRLSCVAV GGNPLPTINW FKGKRRITTG ILNTVSDNAA
QSELAFPVAA SDNSAAYKCS AQNEASTKLL TASVNLTVLF PPSSLSIHVK PDILKVGNIA
QLTCETSSGN PAPVITWWRD GENVAGVDVH NKSGFNGGWV VKSKLYVPLT AEEDGMKYTC
RATTAEIGQS VNEVVSLSVR YSPMFFLRDP QEITVLENET VVLNATASAN PEPIVYEWLK
DGKPMRNSFY KSNKPKVVLS GSVLTINEID RAHSGRYTCK AKNSEGISTM IFIISVKYSA
EITHITESVT KRVGDDVQLE CEATAFPIVD NMIGWERDGF NMSRVSIRHT SEMSMLKISD
INIEDAGAFT CTAYNGIGTR AKKKAWIIVK HAPTVYKNLT YSKVASEVGA EVVLKCLCRG
APQVSWQWKR DDGKELDYDV RFNVQSNQIS PLEYEANKPS QFFTHTKLVI KRVLQNDYGK
YICIARNELG TDQFEIPLRH LSKPDQPTNL TISNISHDAV SLQWRENFDG GLNQLFRIRY
FSWHAPERPL FSPTVNETTI TINGLSPSTK YSFAVEALNR LGSRGFSKST VSAETLRISG
IANQLGIKED IPILVIVLVC LVGVVLLALN AFLVLCFIRR HRNRKLQVLE HKVLVNNNAD
CSPSGKTDDS FSEKAANVRL LEQAQPEAAP YAVVEKLLNG SVNNQESSVQ FESNSNNRAS
QFSEDNMSMR TVIEVDSAGR PIFNKPYGAL EQPSYFNYQS NLDYDNAPSD ALYAESLRAN
TLQRQLMSPL YEDSTAFHGA SDEEFTLPMM GPLRSVSQEL SNYSGFANSP TIRSSSLRRS
VFDRGSPNIS SQASTVGTVV YNNGRSPFAE VRPMPSPQRS GYAVGNSATV NGSSGVNTSL
LSTFPNSVNS RDYMAFDGGL TGDIV
//
