ID A0A0V1BJ74_TRISP Unreviewed; 895 AA.
AC A0A0V1BJ74;
DT 16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT 16-MAR-2016, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=Sodium bicarbonate transporter-like protein 11 {ECO:0000313|EMBL:KRY36961.1};
GN Name=Slc4a11 {ECO:0000313|EMBL:KRY36961.1};
GN ORFNames=T01_4525 {ECO:0000313|EMBL:KRY36961.1};
OS Trichinella spiralis (Trichina worm).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Enoplea; Dorylaimia;
OC Trichinellida; Trichinellidae; Trichinella.
OX NCBI_TaxID=6334 {ECO:0000313|EMBL:KRY36961.1, ECO:0000313|Proteomes:UP000054776};
RN [1] {ECO:0000313|EMBL:KRY36961.1, ECO:0000313|Proteomes:UP000054776}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ISS3 {ECO:0000313|EMBL:KRY36961.1};
RA Korhonen P.K., Edoardo P., Giuseppe L.R., Gasser R.B.;
RT "Evolution of Trichinella species and genotypes.";
RL Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651};
CC Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the anion exchanger (TC 2.A.31) family.
CC {ECO:0000256|ARBA:ARBA00010993}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KRY36961.1}.
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DR EMBL; JYDH01000038; KRY36961.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0V1BJ74; -.
DR STRING; 6334.A0A0V1BJ74; -.
DR InParanoid; A0A0V1BJ74; -.
DR Proteomes; UP000054776; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005452; F:solute:inorganic anion antiporter activity; IEA:InterPro.
DR GO; GO:0006820; P:monoatomic anion transport; IEA:InterPro.
DR Gene3D; 1.10.287.570; Helical hairpin bin; 1.
DR InterPro; IPR011531; HCO3_transpt-like_TM_dom.
DR InterPro; IPR003020; HCO3_transpt_euk.
DR InterPro; IPR016152; PTrfase/Anion_transptr.
DR PANTHER; PTHR11453; ANION EXCHANGE PROTEIN; 1.
DR PANTHER; PTHR11453:SF82; SOLUTE CARRIER FAMILY 4 MEMBER 11; 1.
DR Pfam; PF00955; HCO3_cotransp; 1.
DR PRINTS; PR01231; HCO3TRNSPORT.
DR SUPFAM; SSF55804; Phoshotransferase/anion transport protein; 1.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Ion transport {ECO:0000256|ARBA:ARBA00023065};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000054776};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 413..434
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 454..480
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 492..511
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 592..611
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 631..648
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 669..694
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 714..735
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 776..797
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 875..893
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 382..856
FT /note="Bicarbonate transporter-like transmembrane"
FT /evidence="ECO:0000259|Pfam:PF00955"
FT REGION 1..30
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 60..88
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..15
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 16..30
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 60..84
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 895 AA; 101398 MW; D155D6C73139849E CRC64;
MHAGCEQETQ RRRCSSTTDV AKSNLSNTEN EDADTLLKPL FPSGRIALAS SSTLLYSTPP
KPSLESFQSS SSTALNTYSL RRPRTSQVEP GECLVETHLH QPGHTHRTNS MNRHETGQKY
LTITNSTVSR SSIDLFDEDS INDFDDAEGE EFEKMTLMYA KHEKIPMKDF GSEVRATMDI
DHLLNKAVLL LDLPETSLEE IFNKIIHEMD IQEPEFTSEQ VKNALFTQDA ASQFHILTRT
VQSICTTNIA GSFDFDQTWI CAICMLPTVQ HRHVAITRLI HPTNLGRTMQ DLRFIIIVIA
PSRAKGTKTA LETARTFATL FADLDIRQRL VMAQGEEQFR QTMLMAAKEL AVEQNQYRDR
NLSLHLSDAK EKLIGPNRWY FGRGLKENFC RRLPLYLSDY VDGIRGPKTV QKLLSTVVFL
YFACLLPSIA FGVLNHDNTH GAMGVKQSIF AQALGGLFFS LFGGQPIIIL LTTVPLSIYI
KIIYQISKEF DLEFFALYAC VGLWCQLFLV IYAHMELSNV MKWATRSTEE IFSLFIAVAF
VVEAFKALSN NFKSFYHATA CQMNNATASL NFSSVKSPQT VYVKECHRET SILYLLLMFG
TLWLGLFIYN FRKTWATPYL TRAKREILAD YALPMAVIVM SFTGAYCFRE VKIERFHFNP
RQPIGTIAAI RLLPVGAILA SMGLGFCLSI LFFLDQNITS AIVNNQKNKL RKGSTTHLDL
LVVAILNVFL SLYGLPWMHA ALPHSPLHLR ALADVEERVS QGHVHEVITY VRETRLATLL
SHCLIGVSAL LLLPMPLQLI PRSVLDGLFL YMAVTSLNGN EMFERILLLL TEQAAYPPTH
YIRRVPQRKI HLFTICQLIQ LILLCSFGLA PYPYIEMIFP VICFSFFPIR QVISF
//
