ID A0A0V1BK19_TRISP Unreviewed; 792 AA.
AC A0A0V1BK19;
DT 16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT 16-MAR-2016, sequence version 1.
DT 24-JAN-2024, entry version 22.
DE SubName: Full=Rho guanine nucleotide exchange factor 16 {ECO:0000313|EMBL:KRY36915.1};
GN Name=ARHGEF16 {ECO:0000313|EMBL:KRY36915.1};
GN ORFNames=T01_15845 {ECO:0000313|EMBL:KRY36915.1};
OS Trichinella spiralis (Trichina worm).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Enoplea; Dorylaimia;
OC Trichinellida; Trichinellidae; Trichinella.
OX NCBI_TaxID=6334 {ECO:0000313|EMBL:KRY36915.1, ECO:0000313|Proteomes:UP000054776};
RN [1] {ECO:0000313|EMBL:KRY36915.1, ECO:0000313|Proteomes:UP000054776}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ISS3 {ECO:0000313|EMBL:KRY36915.1};
RA Korhonen P.K., Edoardo P., Giuseppe L.R., Gasser R.B.;
RT "Evolution of Trichinella species and genotypes.";
RL Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KRY36915.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; JYDH01000038; KRY36915.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0V1BK19; -.
DR eggNOG; KOG3523; Eukaryota.
DR Proteomes; UP000054776; Unassembled WGS sequence.
DR GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:InterPro.
DR Gene3D; 1.20.900.10; Dbl homology (DH) domain; 1.
DR InterPro; IPR035899; DBL_dom_sf.
DR InterPro; IPR000219; DH-domain.
DR InterPro; IPR047271; Ephexin-like.
DR InterPro; IPR001849; PH_domain.
DR PANTHER; PTHR12845:SF5; EPHEXIN, ISOFORM D; 1.
DR PANTHER; PTHR12845; GUANINE NUCLEOTIDE EXCHANGE FACTOR; 1.
DR Pfam; PF00621; RhoGEF; 1.
DR SMART; SM00325; RhoGEF; 1.
DR SUPFAM; SSF48065; DBL homology domain (DH-domain); 1.
DR SUPFAM; SSF50729; PH domain-like; 1.
DR PROSITE; PS50010; DH_2; 1.
DR PROSITE; PS50003; PH_DOMAIN; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000054776}.
FT DOMAIN 432..622
FT /note="DH"
FT /evidence="ECO:0000259|PROSITE:PS50010"
FT DOMAIN 725..765
FT /note="PH"
FT /evidence="ECO:0000259|PROSITE:PS50003"
FT REGION 304..335
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 304..324
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 792 AA; 90667 MW; CF3E01F78451A034 CRC64;
MGIEEEKKPV LNLHFSPAEI CVVHVGKPTS QKCSGVGGRF FLFRPRSSLS NFSTSPHLHT
VNCCSNDRST WAVFGEPNSK STTSPMRFSF KFEKIEENSC HRIQLLLKNL HTACSIKGAR
FGRVQIFPLS ISNFSSNRSN VPSINFDQVQ KRIEINRFYS KKKKKKFFNT SKMQTINMGN
RTVKVRQKFT KIEQNGQLCK LKAIDHNNND LKKEIGDENV TWNRVDWTPK RRRKNNLLGL
DEAFSKLKLR GNRQQCDQSI SKRKCISNFP PKFVPKQCNN RNSDNKAILS TPPPELVVVT
FDSNFPQSNN NSTEQQSISP RNFTKEKYNG KRNSNESEEC KLRVKNIKQH KVFPFESYCS
SLWRRKRSKG LPGSAEVSYM KNKSQQIEVS HSPLIVMLKV PPVCRLANLE AIVLCGTIDL
GVLQTMGEDS IYLQEKIFEI VTSEASYLNS LLILTVHFMQ SPKLSGKTDS ESVISAQDHK
ELFSSVHAVR HSSERLFKKL KQSVETSVML DNICDILADH LQKDENVFVN YCRDLAYQQK
KLHYLKENNA KFVEEIALLE KSKLVKNQDL ASFLLQPLQR VTRYPLLIRA IRSQLNANDK
RIASVECALS TAQRVVSLCN ESRRHFQGIE ELFELHSKLI YNHQSPKQFP VITRKRRLIM
KGSFCASEMK KSKTSSANAL LITKQTRNNF LVKDYCDRKS IAVPSFSFDP GTNGQTLLRF
NASFEHKFLV VLKSNHLNAE VRILLATNSQ EDKEKWIRAL NDPSYHCTVD ISSSVLCENL
PNLFSKTKQS TN
//
