ID A0A0V1BKE7_TRISP Unreviewed; 1273 AA.
AC A0A0V1BKE7;
DT 16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT 16-MAR-2016, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE SubName: Full=FERM domain-containing protein {ECO:0000313|EMBL:KRY37335.1};
GN Name=FRMD6 {ECO:0000313|EMBL:KRY37335.1};
GN ORFNames=T01_5816 {ECO:0000313|EMBL:KRY37335.1};
OS Trichinella spiralis (Trichina worm).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Enoplea; Dorylaimia;
OC Trichinellida; Trichinellidae; Trichinella.
OX NCBI_TaxID=6334 {ECO:0000313|EMBL:KRY37335.1, ECO:0000313|Proteomes:UP000054776};
RN [1] {ECO:0000313|EMBL:KRY37335.1, ECO:0000313|Proteomes:UP000054776}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ISS3 {ECO:0000313|EMBL:KRY37335.1};
RA Korhonen P.K., Edoardo P., Giuseppe L.R., Gasser R.B.;
RT "Evolution of Trichinella species and genotypes.";
RL Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KRY37335.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; JYDH01000034; KRY37335.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0V1BKE7; -.
DR STRING; 6334.A0A0V1BKE7; -.
DR InParanoid; A0A0V1BKE7; -.
DR Proteomes; UP000054776; Unassembled WGS sequence.
DR GO; GO:0005856; C:cytoskeleton; IEA:InterPro.
DR CDD; cd14473; FERM_B-lobe; 1.
DR CDD; cd17101; FERM_F1_PTPN13_like; 1.
DR Gene3D; 1.20.80.10; -; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR InterPro; IPR019749; Band_41_domain.
DR InterPro; IPR014352; FERM/acyl-CoA-bd_prot_sf.
DR InterPro; IPR035963; FERM_2.
DR InterPro; IPR019748; FERM_central.
DR InterPro; IPR000299; FERM_domain.
DR InterPro; IPR018979; FERM_N.
DR InterPro; IPR018980; FERM_PH-like_C.
DR InterPro; IPR047145; FRMD6-like.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR029071; Ubiquitin-like_domsf.
DR PANTHER; PTHR13429; FERM DOMAIN (PROTEIN4.1-EZRIN-RADIXIN-MOESIN) FAMILY; 1.
DR PANTHER; PTHR13429:SF5; FERM DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF09380; FERM_C; 1.
DR Pfam; PF00373; FERM_M; 1.
DR Pfam; PF09379; FERM_N; 1.
DR SMART; SM00295; B41; 1.
DR SMART; SM01196; FERM_C; 1.
DR SUPFAM; SSF50729; PH domain-like; 1.
DR SUPFAM; SSF47031; Second domain of FERM; 1.
DR SUPFAM; SSF54236; Ubiquitin-like; 1.
DR PROSITE; PS50057; FERM_3; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000054776}.
FT DOMAIN 59..366
FT /note="FERM"
FT /evidence="ECO:0000259|PROSITE:PS50057"
FT REGION 440..473
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1169..1189
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 440..457
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 458..472
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1273 AA; 139808 MW; DEFF8C3751C5E6F8 CRC64;
MPFECPTGGS SPLAGLVASK SRCSTSMATA RRFCASGPFA GVPVFVSRST NYLLTSGMKY
VDVQLLTGQH LYVAVDVRCK VADIFDCVCA HIGTQMPRLF GLCVRIENEY RFLELSQKFS
KCTPKNWSKS GGSGTDMLGQ PSVILYLRVH TYVDAVRIIS CPIALLHYYM QLRENLRVYW
SPEWVREEQC YEATALALQA DFGDYNENTA AGTVYFSPEL YFPSWVVEYR GVHFLRRHTP
TVHRDCQGMD PQEARYRFCE ELSTGLSAVN VHLYRLKRTK SEQFDSILLG IGPAGIDVFE
PKQDNPRALL GSFQWARISK LSFDRRKFLI CSVDGRKLTF YTSSDQKSRY LLHFCRMFHQ
NLMKLHVDIG SLGNGNYCQD GGDGKIAQKQ CSIYGVIDGT TATSNGETSI QSSDGKITSN
GCDKIFPNLS NATGQRVSLV SDASSNTTSG IVSDKQQAPD DSENDNGELC HRQDRLNIPV
NARSLSDPDL LEFDFSANGK VPLVHSDSAR SEVSFVSRQT YADEEETSST DGSGEVGEFC
STSQAVCSCA ESVAADTTDR NNTKLKTASS NNSNNVEPVH CAVKNSAQIQ HPILPSALAT
LEEKLRRCQL RTREQLALNV KNSLVDISDI RRRTLFNNAD CQPTADRNCN LAQRAYMNWI
PTGGMGSNKL ASASAGSCQD ASCCAQPKQQ QQQQPQQQQQ QQQQQQQCTT ASVNYPMMDS
RYQRRMAPVN AGPMVTSTAS ECLQSVSLSN LPSHALSSAY GSTPLHVDNS NSSLPNYEQA
IRQKAERQHG KRWTTITCVD PFVLNQATSS ISVQCKWNDN NNNNNNEQNE YLRQRNDQLR
QPLQQAQSEP GLGLDARLSS SIGSCAMSDE NCRRPYKKYD IFSNDSFYRE RSLSAYLSGP
TTTTTAECDL AAYTPAAYVN HHHQQQQQQQ QQQYKSTIPC SYAECKELNS SASSGGGCSS
HFLHGSAIVS RTQSLQDSTS SYRHGGALGS GREISFSRLR AKHAVNLGLG QAVSISSSEL
LPSTIANRYQ DSGCSSTSTH YCDACQEEHC EMPAIDLDRV KSMIQAQAAD LPLIRALCSD
QSLHSSSANC CSISELDSTG SSAAGQWSVP VSRRLSMAGN LDDDITGEYC CQEAMTADQQ
AAVSQFGTFE PPITGRPLSW HESFVQQQKK HRHLQLQKPP PTPPPQTTKA TETVEVASAS
VSDCGSVSSL LQCQFLMPPP PPYHGDTSSS SSSCHLSLQK LHENSINDCY AGASSTAQMH
VSLAPASLQS VVR
//
