ID A0A0V1BKH3_TRISP Unreviewed; 1343 AA.
AC A0A0V1BKH3;
DT 16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT 16-MAR-2016, sequence version 1.
DT 24-JAN-2024, entry version 37.
DE RecName: Full=DNA helicase {ECO:0000256|ARBA:ARBA00012551};
DE EC=3.6.4.12 {ECO:0000256|ARBA:ARBA00012551};
GN Name=RUVBL1 {ECO:0000313|EMBL:KRY37441.1};
GN ORFNames=T01_12346 {ECO:0000313|EMBL:KRY37441.1};
OS Trichinella spiralis (Trichina worm).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Enoplea; Dorylaimia;
OC Trichinellida; Trichinellidae; Trichinella.
OX NCBI_TaxID=6334 {ECO:0000313|EMBL:KRY37441.1, ECO:0000313|Proteomes:UP000054776};
RN [1] {ECO:0000313|EMBL:KRY37441.1, ECO:0000313|Proteomes:UP000054776}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ISS3 {ECO:0000313|EMBL:KRY37441.1};
RA Korhonen P.K., Edoardo P., Giuseppe L.R., Gasser R.B.;
RT "Evolution of Trichinella species and genotypes.";
RL Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the RuvB family.
CC {ECO:0000256|ARBA:ARBA00007519}.
CC -!- SIMILARITY: Belongs to the mTERF family.
CC {ECO:0000256|ARBA:ARBA00007692}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KRY37441.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; JYDH01000033; KRY37441.1; -; Genomic_DNA.
DR eggNOG; KOG1267; Eukaryota.
DR eggNOG; KOG1942; Eukaryota.
DR Proteomes; UP000054776; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0008094; F:ATP-dependent activity, acting on DNA; IEA:InterPro.
DR GO; GO:0003690; F:double-stranded DNA binding; IEA:InterPro.
DR GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR Gene3D; 1.10.8.60; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 2.40.50.360; RuvB-like helicase, domain II; 1.
DR Gene3D; 1.25.70.10; Transcription termination factor 3, mitochondrial; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR003690; MTERF.
DR InterPro; IPR038538; MTERF_sf.
DR InterPro; IPR012340; NA-bd_OB-fold.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR027238; RuvB-like.
DR InterPro; IPR041048; RuvB-like_C.
DR InterPro; IPR042487; RuvBL1/2_DNA/RNA_bd_dom.
DR InterPro; IPR010339; TIP49_P-loop.
DR InterPro; IPR001507; ZP_dom.
DR PANTHER; PTHR11093:SF6; RUVB-LIKE 1; 1.
DR PANTHER; PTHR11093; RUVB-RELATED REPTIN AND PONTIN; 1.
DR Pfam; PF02536; mTERF; 1.
DR Pfam; PF06068; TIP49; 2.
DR Pfam; PF17856; TIP49_C; 1.
DR SMART; SM00382; AAA; 1.
DR SMART; SM00733; Mterf; 3.
DR SMART; SM00241; ZP; 1.
DR SUPFAM; SSF50249; Nucleic acid-binding proteins; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51034; ZP_2; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Helicase {ECO:0000256|ARBA:ARBA00022806};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000054776};
KW Transit peptide {ECO:0000256|ARBA:ARBA00022946};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 1270..1293
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1314..1331
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 939..1180
FT /note="ZP"
FT /evidence="ECO:0000259|PROSITE:PS51034"
SQ SEQUENCE 1343 AA; 151481 MW; EF0824B8EC5EECFB CRC64;
MTEFKNEDPM DFVVGSKLVI PVMLPCTTES QLTDLCKPYG TICHQMLVPS ADQKSSLGIV
GFCEFNAADI AVTALASVGT VAFSVYFREA TSAIVVKDQV EETNVESCHK RLNKLRRRCA
VFEYMVDMLD KMSRTILYET TSKMNDFDID YRRFKSNEVL VPNRGSTYAV NVANEMEDSS
ENISAKFPYM YDLLGLKFPL DSAEKNIQST WKKGSSSLNR RFLNIMTVDI LTTNVRTQRV
AAHSHVKGLG LETDGRAKQI GSGFVGQVEA RTAAGVIVDL VKMKRMAGRA VLLAGPPGTG
KTAIALAIAR ELGSKVPFAP MVASEVYSME VKKTEVLMEN IRRCIGYETR LTNLTVGLRT
TKGCTQLKLD PTLYDVFLQQ RIEVGDVIYI ETNSGAVKRV GRCDVYATET DLEAEEFVPL
PKGEIRKQKE FVQDVTLHDL DTANAKPKNL RKEVNASVNR YIEQGIAELV PGVLFIDEAH
MLDMECFTYL HRVIESSFSP IVILATNRGF SKIRGTEIVS AHGIPQDLLE RLLIVKTLPY
GLQEILEIVK IRAKAENVNI TGEALQSLAE IGYRASLRMW QQSFVAFRLF NCAIIRPRCC
CSSRQLREIE NRLFMVNSVE SACESDFPTE KIAKEDFETN RQFLPAYNSK YKPRRYFRSY
TLAPFVNDSE LLRNFVEIGV DLSKLESRSN AVDFLVKLDW KNDVQPMLRF LVLNGIPLEE
IGQYLTRNPW IFQQNLQHLS DRIGYLKSKA FTVDAIAHII NKARYWLNFD IQTIDSRLGW
LQINFKLTGD EVRDVVTKEP KLITFGTGYV QRLQFTFGQE MDRSVLMKSF DYLHNVVGFS
HETILSWPRC LRESSYKARA RHQFLKRLKR DQFDPQRPNY VTVEAMLSGD DGEFCARVAK
CPEAVLSTAS LILLISLLVT LTLAGSDVNN YLVGAPVVDC QDTSISITFS TAKPFTGRVY
VKGLQEDDRC SRSYAGNSEQ RKFTIMVNQG DCSMQRQRVS GGSLEGMMFS MVIVVSFHGT
FETMNDKAFR SVCFFRNIKR VTNFLDVSML PTTELMDTGK MPDCSYTIRK DSPTGPVIRY
AEVGDRLFHV WECEDDGQGL LVHSCWVSDG RGSRFELLDI DGCAIDPVIQ PDIRYEKSLT
RAYVETWAYK YSDTSVLDYQ CIVELCKKSQ GECDTMTPPR CVRSKRASAN VGNKQLRLHA
NRQRRHVVHN SDRQFDLLAD VRVMDSLVVD QEFGNVPKSI IDKLNRVNSG VVRNATASDL
GDRLCLSAPA VGFLLTLIVA LFIAASTTSL LLFTRRGDAD LKNRISLNNK KTDIIPFHIV
IATEMQILPI LKLSLTKLCC FDG
//
