ID A0A0V1BM63_TRISP Unreviewed; 891 AA.
AC A0A0V1BM63;
DT 16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT 16-MAR-2016, sequence version 1.
DT 27-MAR-2024, entry version 33.
DE RecName: Full=dynamin GTPase {ECO:0000256|ARBA:ARBA00011980};
DE EC=3.6.5.5 {ECO:0000256|ARBA:ARBA00011980};
GN Name=dyn-1 {ECO:0000313|EMBL:KRY38054.1};
GN ORFNames=T01_11757 {ECO:0000313|EMBL:KRY38054.1};
OS Trichinella spiralis (Trichina worm).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Enoplea; Dorylaimia;
OC Trichinellida; Trichinellidae; Trichinella.
OX NCBI_TaxID=6334 {ECO:0000313|EMBL:KRY38054.1, ECO:0000313|Proteomes:UP000054776};
RN [1] {ECO:0000313|EMBL:KRY38054.1, ECO:0000313|Proteomes:UP000054776}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ISS3 {ECO:0000313|EMBL:KRY38054.1};
RA Korhonen P.K., Edoardo P., Giuseppe L.R., Gasser R.B.;
RT "Evolution of Trichinella species and genotypes.";
RL Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the TRAFAC class dynamin-like GTPase
CC superfamily. Dynamin/Fzo/YdjA family. {ECO:0000256|RuleBase:RU003932}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KRY38054.1}.
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DR EMBL; JYDH01000028; KRY38054.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0V1BM63; -.
DR STRING; 6334.A0A0V1BM63; -.
DR eggNOG; KOG0446; Eukaryota.
DR InParanoid; A0A0V1BM63; -.
DR Proteomes; UP000054776; Unassembled WGS sequence.
DR GO; GO:0005874; C:microtubule; IEA:UniProtKB-KW.
DR GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR GO; GO:0006897; P:endocytosis; IEA:UniProtKB-KW.
DR CDD; cd08771; DLP_1; 1.
DR CDD; cd01256; PH_dynamin; 1.
DR Gene3D; 1.20.120.1240; Dynamin, middle domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR InterPro; IPR022812; Dynamin.
DR InterPro; IPR001401; Dynamin_GTPase.
DR InterPro; IPR019762; Dynamin_GTPase_CS.
DR InterPro; IPR045063; Dynamin_N.
DR InterPro; IPR000375; Dynamin_stalk.
DR InterPro; IPR030381; G_DYNAMIN_dom.
DR InterPro; IPR003130; GED.
DR InterPro; IPR020850; GED_dom.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR001849; PH_domain.
DR PANTHER; PTHR11566; DYNAMIN; 1.
DR PANTHER; PTHR11566:SF212; DYNAMIN; 1.
DR Pfam; PF01031; Dynamin_M; 1.
DR Pfam; PF00350; Dynamin_N; 1.
DR Pfam; PF02212; GED; 1.
DR Pfam; PF00169; PH; 1.
DR PRINTS; PR00195; DYNAMIN.
DR SMART; SM00053; DYNc; 1.
DR SMART; SM00302; GED; 1.
DR SMART; SM00233; PH; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF50729; PH domain-like; 1.
DR PROSITE; PS00410; G_DYNAMIN_1; 1.
DR PROSITE; PS51718; G_DYNAMIN_2; 1.
DR PROSITE; PS51388; GED; 1.
DR PROSITE; PS50003; PH_DOMAIN; 1.
PE 3: Inferred from homology;
KW Endocytosis {ECO:0000256|ARBA:ARBA00022583};
KW GTP-binding {ECO:0000256|RuleBase:RU003932};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Microtubule {ECO:0000256|ARBA:ARBA00022701};
KW Motor protein {ECO:0000256|ARBA:ARBA00023175};
KW Nucleotide-binding {ECO:0000256|RuleBase:RU003932};
KW Reference proteome {ECO:0000313|Proteomes:UP000054776}.
FT DOMAIN 30..297
FT /note="Dynamin-type G"
FT /evidence="ECO:0000259|PROSITE:PS51718"
FT DOMAIN 519..625
FT /note="PH"
FT /evidence="ECO:0000259|PROSITE:PS50003"
FT DOMAIN 653..744
FT /note="GED"
FT /evidence="ECO:0000259|PROSITE:PS51388"
FT REGION 629..650
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 742..793
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 631..647
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 742..765
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 891 AA; 100530 MW; E74B48EE7EAFDB55 CRC64;
MAWINQGMQQ LIPLVNQLQD AFNKLGVSLA LDLPQIAVVG GQSAGKSSVL EAFVGKDFLP
RGSGIVTRRP LVLQLIHDRS VEYGEFLHKK GQKYGDFELI RAEIEAETER VTGSNKGISP
VPINLRIYSP NVLNLTLIDL PGLTKVPVGD QPHDIETQIR DMILTYVTRE NCLILAVTSA
NTDLATSDAL KLAKEVDPAG QRTIGVITKL DLMDEGTDAR EILENRLLPL RRGYIGVVNR
SQKDIDGRKD IRSALEAERR FFLSHPSYRH MADRMGTTYL QKVLNQQLTN HIRDTLPALR
DRLQRQLLIL EKDVSEYKNF RPDDPSRKTK AMLQMVQQFC ADFEKSIEGS SGKDVSVNEL
SGGAKINRLF HERFPFEIVK MEIDEKELRK EIAYAIRNIH GIRVGLFTPD MAFEAIVKKQ
ISRLKEPSLK CVDLVVTELG NVIRMCAEMM SRYPRLMEEV ERIVTTHLRD REQKCKDQLI
LLVEYELAYM NTNHEDFIGF ANAEAKASAV QRQKKLGNQV IRKGWLTIHN VSFIKGGSRD
FWFVLSSDNL SWYKDDEEKE KKYMLPLDGL KLRDIEAGFM SRTHKFALFY PDNKNVYKDY
RQLELSAITP DEVDAWKASF LRAGVYPEKE STAGAEERQE DNSSMDPQLE RQVETIRNLV
DSYMRIVTKT IRDLVPKAIM HLMIHNTNDF IHHELLAHLY QSGDQDSMME ESEAESQRRE
EMLRMYHACK EALRIIGDVS LNTTPSTISS TSNGGGSSSH DWLKNDNQII PPRPVVNGPP
SPNLPRPASG AALRPAPMPV GVQASSVPTV GGGGAGIQIP KIPSRPAPTL NQMGAGSLPP
PLIPQYYSPL ASKVIIAICQ KYGQIVWQLY PPYNKPAPKI PDRPAVTHRH Y
//
