ID   A0A0V1C071_TRISP        Unreviewed;       388 AA.
AC   A0A0V1C071;
DT   16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT   16-MAR-2016, sequence version 1.
DT   22-FEB-2023, entry version 14.
DE   SubName: Full=Transmembrane protein {ECO:0000313|EMBL:KRY42715.1};
GN   Name=TMEM120B {ECO:0000313|EMBL:KRY42715.1};
GN   ORFNames=T01_11709 {ECO:0000313|EMBL:KRY42715.1};
OS   Trichinella spiralis (Trichina worm).
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Enoplea; Dorylaimia;
OC   Trichinellida; Trichinellidae; Trichinella.
OX   NCBI_TaxID=6334 {ECO:0000313|EMBL:KRY42715.1, ECO:0000313|Proteomes:UP000054776};
RN   [1] {ECO:0000313|EMBL:KRY42715.1, ECO:0000313|Proteomes:UP000054776}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ISS3 {ECO:0000313|EMBL:KRY42715.1};
RA   Korhonen P.K., Edoardo P., Giuseppe L.R., Gasser R.B.;
RT   "Evolution of Trichinella species and genotypes.";
RL   Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the TMEM120 family.
CC       {ECO:0000256|ARBA:ARBA00009700}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KRY42715.1}.
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DR   EMBL; JYDH01000003; KRY42715.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A0V1C071; -.
DR   Proteomes; UP000054776; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR   Gene3D; 3.30.900.10; HORMA domain; 1.
DR   InterPro; IPR036570; HORMA_dom_sf.
DR   InterPro; IPR012926; TACAN/TMEM120B.
DR   PANTHER; PTHR21433:SF0; TRANSMEMBRANE PROTEIN 120 HOMOLOG; 1.
DR   PANTHER; PTHR21433; TRANSMEMBRANE PROTEIN INDUCED BY TUMOR NECROSIS FACTOR ALPHA; 1.
DR   Pfam; PF07851; TMPIT; 1.
DR   SUPFAM; SSF56019; The spindle assembly checkpoint protein mad2; 1.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000054776};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        130..149
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        155..174
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        186..204
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        216..239
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        260..278
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        298..323
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
SQ   SEQUENCE   388 AA;  45729 MW;  2CF05CECF84D90B4 CRC64;
     MDLQISVSDC RTALSNFQSR VSDFEISFKD HLSMRTSVGQ FQVSARKTLT HLLHEVSELK
     KITKLSILDE EECKTELSKL NNYEMRFDEM LSHLPCENNG IYLNIILGNI SVSILNRMQR
     IRYKEDYEKF KLRVNLILFV FAPIVYFVHL RVLDAAYNFF LVWYYCTLTI RESILRCNGS
     RIKGWWLFHH YASAVLSGIM LTWPDGECYQ NSRKQILLFS FYISFVTFLQ CQYQRGCLYR
     LKALGRRHSM DITVEGFHTW MFRGLTFLLP FLIIGYVFQL YNAYLLYHLS QTYQCREWQV
     SVLALVFLLM ATGNTLTTAE VCFHKVRHRL GVRDRLRSFD CFAYTDCEVE CPDDWSELKP
     KTVTTEQMIN LGSFNVGFYS IDLTVCYK
//