ID A0A0V1C2D5_TRISP Unreviewed; 383 AA.
AC A0A0V1C2D5;
DT 16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT 16-MAR-2016, sequence version 1.
DT 27-MAR-2024, entry version 30.
DE RecName: Full=Protein Wnt {ECO:0000256|RuleBase:RU003500};
GN Name=WNT16 {ECO:0000313|EMBL:KRY43320.1};
GN ORFNames=T01_14884 {ECO:0000313|EMBL:KRY43320.1};
OS Trichinella spiralis (Trichina worm).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Enoplea; Dorylaimia;
OC Trichinellida; Trichinellidae; Trichinella.
OX NCBI_TaxID=6334 {ECO:0000313|EMBL:KRY43320.1, ECO:0000313|Proteomes:UP000054776};
RN [1] {ECO:0000313|EMBL:KRY43320.1, ECO:0000313|Proteomes:UP000054776}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ISS3 {ECO:0000313|EMBL:KRY43320.1};
RA Korhonen P.K., Edoardo P., Giuseppe L.R., Gasser R.B.;
RT "Evolution of Trichinella species and genotypes.";
RL Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Ligand for members of the frizzled family of seven
CC transmembrane receptors. {ECO:0000256|RuleBase:RU003500}.
CC -!- SUBCELLULAR LOCATION: Secreted, extracellular space, extracellular
CC matrix {ECO:0000256|ARBA:ARBA00004498, ECO:0000256|RuleBase:RU003500}.
CC -!- SIMILARITY: Belongs to the Wnt family. {ECO:0000256|ARBA:ARBA00005683,
CC ECO:0000256|RuleBase:RU003500}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KRY43320.1}.
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DR EMBL; JYDH01000001; KRY43320.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0V1C2D5; -.
DR STRING; 6334.A0A0V1C2D5; -.
DR InParanoid; A0A0V1C2D5; -.
DR Proteomes; UP000054776; Unassembled WGS sequence.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-KW.
DR GO; GO:0005102; F:signaling receptor binding; IEA:InterPro.
DR GO; GO:0048699; P:generation of neurons; IEA:UniProt.
DR GO; GO:0016055; P:Wnt signaling pathway; IEA:UniProtKB-KW.
DR CDD; cd19344; Wnt_Wnt16; 1.
DR Gene3D; 3.30.2460.20; -; 1.
DR InterPro; IPR005817; Wnt.
DR InterPro; IPR043158; Wnt_C.
DR InterPro; IPR018161; Wnt_CS.
DR PANTHER; PTHR12027:SF70; PROTEIN WNT-16; 1.
DR PANTHER; PTHR12027; WNT RELATED; 1.
DR Pfam; PF00110; wnt; 1.
DR PRINTS; PR01349; WNTPROTEIN.
DR SMART; SM00097; WNT1; 1.
DR PROSITE; PS00246; WNT1; 1.
PE 3: Inferred from homology;
KW Developmental protein {ECO:0000256|ARBA:ARBA00022473,
KW ECO:0000256|RuleBase:RU003500};
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW Extracellular matrix {ECO:0000256|ARBA:ARBA00022530};
KW Reference proteome {ECO:0000313|Proteomes:UP000054776};
KW Secreted {ECO:0000256|ARBA:ARBA00022525}; Signal {ECO:0000256|SAM:SignalP};
KW Wnt signaling pathway {ECO:0000256|ARBA:ARBA00022687,
KW ECO:0000256|RuleBase:RU003500}.
FT SIGNAL 1..22
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 23..383
FT /note="Protein Wnt"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5006875606"
SQ SEQUENCE 383 AA; 44492 MW; 6D24C31B17414543 CRC64;
MTQFFPLMII CSCYYIAQIA EANWLYLAIH QPFAFTVDPQ YSYLRAMLTQ EQAHRICSSL
LYLNEQQRRV CAAHPYTMHS VSVGIRLAIA ECQWQFRPER WNCTPIRGAN ESAFDIFGTM
LKSGNRESAF LEAITTAGLV HAIVTACTTG NLTDCSCDMS KNGLEGFRVK SRPDDASENW
RWGGCSDNIR YGIIFAREFL DKHVRKQFQQ NKDSRDLVIL HNQEVGRKAI SENMKRHCRC
HGISGSCEMK TCWQQMPKMK EVSEQLKLFY DRSSIQVTKR AKRKLRRKNK YERKIPLRIS
ELVYQNRSPN YCVRDDKMGL LGTYGRQCNR TTLSSDSCDL LCCGRGYDTR LVTKYERCHC
KFVWCCYVTC KACNWNVEMH TCK
//
