ID A0A0V1CAJ9_TRIBR Unreviewed; 1038 AA.
AC A0A0V1CAJ9;
DT 16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT 16-MAR-2016, sequence version 1.
DT 22-FEB-2023, entry version 26.
DE SubName: Full=Protein diaphanous-like protein 3 {ECO:0000313|EMBL:KRY46272.1};
GN Name=Diaph3 {ECO:0000313|EMBL:KRY46272.1};
GN ORFNames=T03_281 {ECO:0000313|EMBL:KRY46272.1};
OS Trichinella britovi (Parasitic roundworm).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Enoplea; Dorylaimia;
OC Trichinellida; Trichinellidae; Trichinella.
OX NCBI_TaxID=45882 {ECO:0000313|EMBL:KRY46272.1, ECO:0000313|Proteomes:UP000054653};
RN [1] {ECO:0000313|EMBL:KRY46272.1, ECO:0000313|Proteomes:UP000054653}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ISS120 {ECO:0000313|EMBL:KRY46272.1};
RA Korhonen P.K., Edoardo P., Giuseppe L.R., Gasser R.B.;
RT "Evolution of Trichinella species and genotypes.";
RL Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the formin homology family. Diaphanous
CC subfamily. {ECO:0000256|ARBA:ARBA00008214}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KRY46272.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; JYDI01000298; KRY46272.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0V1CAJ9; -.
DR Proteomes; UP000054653; Unassembled WGS sequence.
DR GO; GO:0003779; F:actin binding; IEA:InterPro.
DR GO; GO:0031267; F:small GTPase binding; IEA:InterPro.
DR GO; GO:0030036; P:actin cytoskeleton organization; IEA:InterPro.
DR Gene3D; 1.20.58.630; -; 1.
DR Gene3D; 6.10.30.30; -; 1.
DR Gene3D; 1.10.20.40; Formin, diaphanous GTPase-binding domain; 1.
DR Gene3D; 1.20.58.2220; Formin, FH2 domain; 1.
DR Gene3D; 1.10.238.150; Formin, FH3 diaphanous domain; 1.
DR Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 1.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR014767; DAD_dom.
DR InterPro; IPR044933; DIA_GBD_sf.
DR InterPro; IPR015425; FH2_Formin.
DR InterPro; IPR042201; FH2_Formin_sf.
DR InterPro; IPR010472; FH3_dom.
DR InterPro; IPR014768; GBD/FH3_dom.
DR InterPro; IPR010473; GTPase-bd.
DR PANTHER; PTHR45691; PROTEIN DIAPHANOUS; 1.
DR PANTHER; PTHR45691:SF6; PROTEIN DIAPHANOUS; 1.
DR Pfam; PF06367; Drf_FH3; 1.
DR Pfam; PF06371; Drf_GBD; 1.
DR Pfam; PF02181; FH2; 1.
DR SMART; SM01139; Drf_FH3; 1.
DR SMART; SM01140; Drf_GBD; 1.
DR SMART; SM00498; FH2; 1.
DR SUPFAM; SSF48371; ARM repeat; 1.
DR SUPFAM; SSF101447; Formin homology 2 domain (FH2 domain); 1.
DR PROSITE; PS51231; DAD; 1.
DR PROSITE; PS51444; FH2; 1.
DR PROSITE; PS51232; GBD_FH3; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000054653}.
FT DOMAIN 70..439
FT /note="GBD/FH3"
FT /evidence="ECO:0000259|PROSITE:PS51232"
FT DOMAIN 504..898
FT /note="FH2"
FT /evidence="ECO:0000259|PROSITE:PS51444"
FT DOMAIN 920..955
FT /note="DAD"
FT /evidence="ECO:0000259|PROSITE:PS51231"
FT REGION 1..44
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 993..1020
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 486..513
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 881..912
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 1005..1020
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1038 AA; 118793 MW; D3355A64C2D60EF5 CRC64;
MNQRREKNWS ILGKVGNSFR HTSKHGKDSS KCDGNGDDSW TVTDSQRPAY EHNTLHGLPN
TSTAVSEYDI DSLSSKELDL IFEDMLNDMN LSEAKKAPLR TASIEQKRVM ILQKIRTDQT
LRGAKVKCDD PGDYIRILSA SEDNSPKLVR ILQSLRVSLS NNPVSWIEKF GTRGLNLLLN
ILQWVSENPL VEASSMRIQH ECIKCLRAFM NNNYGLRQIM EHNQSCEILV QSLNVVNQSS
TIDAVKLLAA ICVMPSPNST VQSGHEKVLN ALSSYAEHSE IRRFVPIVQG LGVAANPALQ
NAFMQLVNAI ITIADDLDYR MHLRNEFMRT GMTDVLEIME CSENEDLKLQ VKIFTENRDA
DLDELFQRHE NLRIEMDSPR KCYEALEHSL RNSPTSYYFL SILQHLLFIR DDDVELRTSY
YKLLDDVISS VVLHKSGYEV DVHNQKRLAL NIEDLLEKVT EHQKHDLDSI GSSSDRLASE
DMKVKFEAVV TENQELEAKL TQLASKIEEY KNETFNLRQH VDPSQMIESS FWAKTEEERF
KSKTFFHHLE EHFSTASTAN GNLTSFQKKT IKKVKEAKVL PPNAVKTLEI IHGSTKMSAA
EFRDALLELD ESKLTENILE RFWKIFSEPE LVSNLKSIQG EFNDLAGVEQ FAITLTSIRA
LSVRLQCMCF KKKFSELIAD IKPSIVAVTA ACDEIKTSKG FGLFLEYVLL AGNYMNSCGK
NTLAYGFLFS ILSKLREVKS IRQDVTLMHV LYEIFSKSFP EYAKFTDDFI HLNKAAEVKT
EIVQQGINQM KNNITVLENS LKNYNRQAEN DNYVEVMSSF LTVAREQFQL LETMHKKMQD
VCRSLLKYFS FDSKTYPVDQ CLADLRDFKV AYEKTAKEIA FAKEKENRIR LAEEARALKE
KEMQERKQQK MKLIEMTRGD QEGVMDSLLE ALSSGKAFPQ RAKTPAREKS RMRRRNSQFN
HVTIVNVSGD TVSADRERTP KMNSNDAPKM RIRRKGKKTV DPLSDGQKFN ASNGHNSEVH
YQDASDLEDL LRRLKCDF
//
