ID A0A0V1CBW9_TRIBR Unreviewed; 308 AA.
AC A0A0V1CBW9;
DT 16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT 16-MAR-2016, sequence version 1.
DT 27-MAR-2024, entry version 14.
DE SubName: Full=Very-long-chain enoyl-CoA reductase {ECO:0000313|EMBL:KRY46494.1};
GN Name=TECR {ECO:0000313|EMBL:KRY46494.1};
GN ORFNames=T03_2728 {ECO:0000313|EMBL:KRY46494.1};
OS Trichinella britovi (Parasitic roundworm).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Enoplea; Dorylaimia;
OC Trichinellida; Trichinellidae; Trichinella.
OX NCBI_TaxID=45882 {ECO:0000313|EMBL:KRY46494.1, ECO:0000313|Proteomes:UP000054653};
RN [1] {ECO:0000313|EMBL:KRY46494.1, ECO:0000313|Proteomes:UP000054653}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ISS120 {ECO:0000313|EMBL:KRY46494.1};
RA Korhonen P.K., Edoardo P., Giuseppe L.R., Gasser R.B.;
RT "Evolution of Trichinella species and genotypes.";
RL Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the steroid 5-alpha reductase family.
CC {ECO:0000256|ARBA:ARBA00007742}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KRY46494.1}.
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DR EMBL; JYDI01000285; KRY46494.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0V1CBW9; -.
DR Proteomes; UP000054653; Unassembled WGS sequence.
DR GO; GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0016627; F:oxidoreductase activity, acting on the CH-CH group of donors; IEA:InterPro.
DR GO; GO:0006629; P:lipid metabolic process; IEA:InterPro.
DR InterPro; IPR001104; 3-oxo-5_a-steroid_4-DH_C.
DR InterPro; IPR039357; SRD5A/TECR.
DR InterPro; IPR049127; TECR-like_N.
DR PANTHER; PTHR10556; 3-OXO-5-ALPHA-STEROID 4-DEHYDROGENASE; 1.
DR PANTHER; PTHR10556:SF28; VERY-LONG-CHAIN ENOYL-COA REDUCTASE; 1.
DR Pfam; PF02544; Steroid_dh; 1.
DR Pfam; PF21696; TECR_N; 1.
DR PROSITE; PS50244; S5A_REDUCTASE; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000054653};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 168..186
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 192..215
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 197..282
FT /note="Steroid 5-alpha reductase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS50244"
SQ SEQUENCE 308 AA; 35590 MW; 2443ABFD34DC8AA8 CRC64;
MTLAEIEIYD CRTLRMMLVL RSLPLTATIL DVKFEITRKK PGFAVESQSL RLQSTGGKNL
SDECQLDTLP KIDGRIQLYV KDLGPQIQWK TVFLLEYIGP LIVYPMFFFR LPLIYEYQYV
NQIPTSWVVR LALGCWTLHY VKRVCETLYV HRFSHSTMPL RNLFKNCAYY WGFAAFVGFH
VNHPFYTEPK AAIALIGLVG FLLAELGNYS IHAALSNLRP VGSKERKIPM PTENPFTLLF
NLVSVPNYTY EIIAWFCFSM MTQCLPALLF TILGAIQMTI WACAKQKAYK REFPHYPAER
KAIIPFLI
//
