ID A0A0V1CR47_TRIBR Unreviewed; 490 AA.
AC A0A0V1CR47;
DT 16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT 16-MAR-2016, sequence version 1.
DT 27-MAR-2024, entry version 33.
DE SubName: Full=Nuclear receptor subfamily 4 group A member 1 {ECO:0000313|EMBL:KRY51624.1};
GN Name=NR4A1 {ECO:0000313|EMBL:KRY51624.1};
GN ORFNames=T03_14322 {ECO:0000313|EMBL:KRY51624.1};
OS Trichinella britovi (Parasitic roundworm).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Enoplea; Dorylaimia;
OC Trichinellida; Trichinellidae; Trichinella.
OX NCBI_TaxID=45882 {ECO:0000313|EMBL:KRY51624.1, ECO:0000313|Proteomes:UP000054653};
RN [1] {ECO:0000313|EMBL:KRY51624.1, ECO:0000313|Proteomes:UP000054653}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ISS120 {ECO:0000313|EMBL:KRY51624.1};
RA Korhonen P.K., Edoardo P., Giuseppe L.R., Gasser R.B.;
RT "Evolution of Trichinella species and genotypes.";
RL Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KRY51624.1}.
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DR EMBL; JYDI01000121; KRY51624.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0V1CR47; -.
DR Proteomes; UP000054653; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-KW.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR CDD; cd06969; NR_DBD_NGFI-B; 1.
DR Gene3D; 3.30.50.10; Erythroid Transcription Factor GATA-1, subunit A; 1.
DR Gene3D; 1.10.565.10; Retinoid X Receptor; 1.
DR InterPro; IPR035500; NHR-like_dom_sf.
DR InterPro; IPR000536; Nucl_hrmn_rcpt_lig-bd.
DR InterPro; IPR001723; Nuclear_hrmn_rcpt.
DR InterPro; IPR001628; Znf_hrmn_rcpt.
DR InterPro; IPR013088; Znf_NHR/GATA.
DR PANTHER; PTHR24085; NUCLEAR HORMONE RECEPTOR; 1.
DR PANTHER; PTHR24085:SF4; NUCLEAR HORMONE RECEPTOR HR38-RELATED; 1.
DR Pfam; PF00104; Hormone_recep; 1.
DR Pfam; PF00105; zf-C4; 1.
DR PRINTS; PR00398; STRDHORMONER.
DR PRINTS; PR00047; STROIDFINGER.
DR SMART; SM00399; ZnF_C4; 1.
DR SUPFAM; SSF57716; Glucocorticoid receptor-like (DNA-binding domain); 1.
DR SUPFAM; SSF48508; Nuclear receptor ligand-binding domain; 1.
DR PROSITE; PS51843; NR_LBD; 1.
DR PROSITE; PS00031; NUCLEAR_REC_DBD_1; 1.
DR PROSITE; PS51030; NUCLEAR_REC_DBD_2; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Receptor {ECO:0000256|ARBA:ARBA00023170, ECO:0000313|EMBL:KRY51624.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000054653};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771}.
FT DOMAIN 237..312
FT /note="Nuclear receptor"
FT /evidence="ECO:0000259|PROSITE:PS51030"
FT DOMAIN 333..490
FT /note="NR LBD"
FT /evidence="ECO:0000259|PROSITE:PS51843"
SQ SEQUENCE 490 AA; 54051 MW; E204903506F3315A CRC64;
MLYVEQMHRA RQFFGATPQI SGAGQASTFV EEPTTMWCDL PGSSYKMFDR PYREQQPASG
LTVLPSSCLS SNYVRTEDQY PQLHAAESAS SCTQQAPTYF PIAPNEPSLP STYGYLTGTT
TPQTAGSRMQ QRITRAFSSP EIETPQLASM LSAYANPDSM YLSHSLPCVQ STYIPEPNEA
LLSNRWEPQT TPPSSHSSSC VSPTCHQVAF FSDTIAHSSS TFGSSSLAPS GSPSQTNQTC
AVCGDHAACQ HYGVRTCEGC KGFFKRTVQK NAKYVCMGSR DCVIDKRRRN RCQYCRFQKC
MAVGMVKEVV RMDSLKGRRG RLPSRSKVAD DSSSTSLTSS LVHAHMVHVI AKSSTEAMAP
GDFFMNTDES LLSSLNYSLA VVHRWAERLP GWSTLSASDQ RQLLKAGSMN VMHIRIAYRS
MDNVNESGVG NLTFEDGSVR RVDDFRQFWH PWFNALTSLT CHFGHVLDLD LTAVACLTAL
AILMNGKILK
//
