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Database: UniProt
Entry: A0A0V1CUW8_TRIBR
LinkDB: A0A0V1CUW8_TRIBR
Original site: A0A0V1CUW8_TRIBR 
ID   A0A0V1CUW8_TRIBR        Unreviewed;      2676 AA.
AC   A0A0V1CUW8;
DT   16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT   16-MAR-2016, sequence version 1.
DT   07-NOV-2018, entry version 13.
DE   SubName: Full=Inositol 1,4,5-trisphosphate receptor itr-1 {ECO:0000313|EMBL:KRY53109.1};
GN   Name=itr-1 {ECO:0000313|EMBL:KRY53109.1};
GN   ORFNames=T03_1892 {ECO:0000313|EMBL:KRY53109.1};
OS   Trichinella britovi (Parasitic roundworm).
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Enoplea; Dorylaimia;
OC   Trichinellida; Trichinellidae; Trichinella.
OX   NCBI_TaxID=45882 {ECO:0000313|EMBL:KRY53109.1, ECO:0000313|Proteomes:UP000054653};
RN   [1] {ECO:0000313|EMBL:KRY53109.1, ECO:0000313|Proteomes:UP000054653}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ISS120 {ECO:0000313|EMBL:KRY53109.1};
RA   Korhonen P.K., Edoardo P., Giuseppe L.R., Gasser R.B.;
RT   "Evolution of Trichinella species and genotypes.";
RL   Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an
CC       EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is
CC       preliminary data. {ECO:0000313|EMBL:KRY53109.1}.
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DR   EMBL; JYDI01000093; KRY53109.1; -; Genomic_DNA.
DR   Proteomes; UP000054653; Unassembled WGS sequence.
DR   GO; GO:0005783; C:endoplasmic reticulum; IEA:InterPro.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0070679; F:inositol 1,4,5 trisphosphate binding; IEA:InterPro.
DR   GO; GO:0005220; F:inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity; IEA:InterPro.
DR   InterPro; IPR014821; Ins145_P3_rcpt.
DR   InterPro; IPR000493; InsP3_rcpt.
DR   InterPro; IPR005821; Ion_trans_dom.
DR   InterPro; IPR036300; MIR_dom_sf.
DR   InterPro; IPR016093; MIR_motif.
DR   InterPro; IPR013662; RIH_assoc-dom.
DR   InterPro; IPR000699; RIH_dom.
DR   InterPro; IPR015925; Ryanodine_recept-rel.
DR   InterPro; IPR035910; RyR/IP3R_RIH_dom_sf.
DR   PANTHER; PTHR13715; PTHR13715; 2.
DR   Pfam; PF08709; Ins145_P3_rec; 1.
DR   Pfam; PF00520; Ion_trans; 1.
DR   Pfam; PF02815; MIR; 1.
DR   Pfam; PF08454; RIH_assoc; 1.
DR   Pfam; PF01365; RYDR_ITPR; 2.
DR   PRINTS; PR00779; INSP3RECEPTR.
DR   SMART; SM00472; MIR; 3.
DR   SUPFAM; SSF100909; SSF100909; 2.
DR   SUPFAM; SSF82109; SSF82109; 2.
DR   PROSITE; PS50919; MIR; 4.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Complete proteome {ECO:0000313|Proteomes:UP000054653};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Receptor {ECO:0000313|EMBL:KRY53109.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000054653};
KW   Repeat {ECO:0000256|SAAS:SAAS00903904};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   2249   2271       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   2283   2300       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   2306   2324       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   2331   2350       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   2370   2395       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   2415   2437       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   2517   2536       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN      120    174       MIR. {ECO:0000259|PROSITE:PS50919}.
FT   DOMAIN      246    302       MIR. {ECO:0000259|PROSITE:PS50919}.
FT   DOMAIN      309    384       MIR. {ECO:0000259|PROSITE:PS50919}.
FT   DOMAIN      390    447       MIR. {ECO:0000259|PROSITE:PS50919}.
FT   COILED       94    114       {ECO:0000256|SAM:Coils}.
FT   COILED     1148   1168       {ECO:0000256|SAM:Coils}.
FT   COILED     2655   2675       {ECO:0000256|SAM:Coils}.
SQ   SEQUENCE   2676 AA;  307529 MW;  7329157D6898D7A4 CRC64;
     MSAVDVFSST FLHIGDEVSL YAEGSDGTNG FLSTLGLVDD RCVVRPAFGT PENPPKKFRD
     CIFKICPVRR YAAQKQLWAE ERTRQTNGMS SMTLDMMMRL KDAAEKEREQ NQLEFEKTVG
     QIVQYGTTLQ LLHVKSNKFL TVNKKEPARV DRNAMKVTLD AQGNDGSWFT VEPFYKLRSL
     GDNVVAGDRI CLVPYYVAQI PGSQKHQLHV SSLSLAEDSE SKEVNCLNDQ TCWQVLLFLE
     YRENLPDVLK GGDVVRLFHA EQQKFLTQDS RNGVQTVFLR VTKRDQALEA TSSKALWEVE
     VIQQEPHKSG AAKWSSTFRF KHLATDMYLA VLEDEQSKKK PFPMSKEFKK KSSKSSSMEP
     TYSLVSVIPA SPRDPATLFQ LDPTTLTKMD AYIPRQSYIR LKHVQTKNWV HSTTTRCDPE
     KGDESVMLKL GCSNWKEDKE AFAILSVMPG EVRDLDFAND ACKALADFLQ RIRHGLNVMK
     EKGMIMELLA ELIYFVTNAK NHLEDPLKIK PNKVNRNRQK LLREQKVLAQ IFDLLRAPFE
     SRKDQRPLFE NPSVLSKPGN ESFKRMFQLM YTVLRFSQQS YRRNQVYIAE RFIDIQHQIG
     HGLMAEDTIT AVLHDNAKLL ETHVEKTHIE KFIELVRQNR EGRFLDYLTL LCVCKNEANK
     KIQELICLLV LNDANRDILL ETRMFGDQVF IGWLNDESEE LEKLAYETMN SPEAERIVNY
     YKHQLDLFSH MCLDRQFLAI DPPANKHLLN LSQELPISVI LRCMVNERLP YDLRANFARL
     MLHLHVITDL QEVMPVRYAR LWKEIPETVS VEKYTNEEIY SFNQKQRRLF ARSRFTGLLT
     YVEEYLRHVK TAKFSHKAQN VFTLEIVNLA HALVKFGFYS LPELLVLAQD LLDILDNCSL
     DMERVSNGAV VGAVVPNRTE ENMKMEVSSF IESEKQPSDH EDGKTVNLKT KLTIVEILQY
     VLNVRLDYRI TYLLSLIKKE YASSDTGDVG FYEDLDDLKI TQFAHEVFYS KSHCVEVDVE
     KEDFNCRLEL GRENGKQLLR ILLQIMLSDY PPLISLGLSV FYQSFNQRNE LVQALKQLQL
     LVSQMDVQNY QQVHRDLVLM KNLVEKSELW VYSAKTGSQK RSLFPITNDK KSTEDEPLQR
     FDNDLVELIN VEEEKKNMMK LFKELNCKYP MSSEHCRKLL SDILNNWVKL CYADERRPDA
     RNQQLLRNMR VYEVVIEFLS IPFDKKIDSE MPKLFDLAHQ FLCGFCNDNE ENQRLLHQRL
     SLNTDASKCD YLAIEEPRDI ETLCAIFRGN RELCANVSDQ LIQHVVHLIE SKGRNAIFLQ
     FLQTLIPEER TISLTQEKIS QVISTSSEDV CLFYTDSAGF EAMMSLMKQS VDLSDLCNPL
     RYHIELVRLL ALCTVGKNVT TELQCASHIP LEHIVRVITD EQCFYEIKEV YLQFLLHCYI
     DTDADMKDMY CDDCMAQILA NVLDDVEQLY ERGPSINGSV ERYICLTVTK LLICFFEQPC
     AQCFSDPKHE NGIFGRLLEA LGRLQSIDWL RRQNAIYKSN LINCVETMCK FAHDQRLAVT
     VDMIMRKEGK SSKWTKLKKA KYFVTQAAHM TRKGHDFNNI VDCFHEIVCR MEDLFGPMAR
     AETMVAVDVL HYPDLTFYDT QSNMKRYSDG EFVTKLIKHC RLLAYDKNEQ LCIKLLDTIR
     SMIPAEQDLD TSTMNSRKDL LLQYLGIHGP GRSGKAKSFK DDDQERWTTM LKKILPQNIT
     SVQCSLNAAG ASKLVIDLIV HCSSENIFIA AVELGKTLLE GGNRVVQNSF LECLTSGGVG
     ENFFRVFNEK MQRAQNKLRS SILSRRDRIG GSRMTSRSFM SGSSQTSAVG QAHDEAIRKI
     QDQLKLWSDD DWVGGSESSD IRTERCWREQ DKVDADFLLP AEVTIMEPIL RLLQLLCENH
     NPALQNFLRC QENRTNYNMV TETLMFLDTI CGSTSGSLGL LHEINEHNVS LVNQALISLT
     EYCQGPCHEN QNAIAMHESN GLDIIISLVL NEIMPLAEKN IQLALEIKSN ASKLLLAILE
     SRNDCDNAER ILRNMARMAG GAEQLVSAIT DVFKLPEISF NHSGYAEKIA SQFDTPKIVF
     ETKTDINGNP VENDGYCEVS PSEVGHNIYI LAHQLSKYYP KLNSMLKPSN ARDEISRSAL
     QFYTDHTAHI EVVRSDRSLE LIIFPVPHVC KFLTEETKER VFLKTERDLQ GSKVPEFFAN
     FDTLYNEIVW QQKLRDKPWL YKCSRSVPIW MRMSFIFAMI LNFLVALFYP FDSAFGAAIN
     TEISGFYLLC LLATTTYTFT APTWTAVAVT STFVASSCVS LFGVTVASYL FGLLQIANNI
     VHTVGIIGSY GPMKLTLASF LSNSNVVYNM FYLLLCLCGL FVHEFFYCFL LFDIVLHEET
     LCNVIRSVTR NWRSIALTGI LAVILVYTFS MVGFVLFSND FWIEVEPNDQ TCAQSENCTE
     TTNVPGEPVK VPFCESLRTC ILAVLRWGLS SGGGIGDVLR KPHPQEPLFY MRILYDLSFY
     FILIVIVLNL IFGVIIDTFA DLRNEKQENE EIIRNTCFIC GLERSHFENK PVSFDEHIKN
     DHNIWNYFYF YVLLNTKSST EFTGPESYVY DMIKEGNVDW FPRMRTMKLA IQEGDSEQTE
     VKILQRMICE RQEEISNLAA RIDELKQMVL KLSRSK
//
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