ID A0A0V1CVM9_TRIBR Unreviewed; 488 AA.
AC A0A0V1CVM9;
DT 16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT 16-MAR-2016, sequence version 1.
DT 24-JAN-2024, entry version 19.
DE SubName: Full=Acetylcholine receptor subunit alpha-type acr-16 {ECO:0000313|EMBL:KRY53100.1};
DE Flags: Fragment;
GN Name=acr-16 {ECO:0000313|EMBL:KRY53100.1};
GN ORFNames=T03_7726 {ECO:0000313|EMBL:KRY53100.1};
OS Trichinella britovi (Parasitic roundworm).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Enoplea; Dorylaimia;
OC Trichinellida; Trichinellidae; Trichinella.
OX NCBI_TaxID=45882 {ECO:0000313|EMBL:KRY53100.1, ECO:0000313|Proteomes:UP000054653};
RN [1] {ECO:0000313|EMBL:KRY53100.1, ECO:0000313|Proteomes:UP000054653}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ISS120 {ECO:0000313|EMBL:KRY53100.1};
RA Korhonen P.K., Edoardo P., Giuseppe L.R., Gasser R.B.;
RT "Evolution of Trichinella species and genotypes.";
RL Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU01005}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KRY53100.1}.
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DR EMBL; JYDI01000093; KRY53100.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0V1CVM9; -.
DR Proteomes; UP000054653; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005230; F:extracellular ligand-gated monoatomic ion channel activity; IEA:InterPro.
DR GO; GO:0004888; F:transmembrane signaling receptor activity; IEA:InterPro.
DR CDD; cd18989; LGIC_ECD_cation; 1.
DR Gene3D; 2.70.170.10; Neurotransmitter-gated ion-channel ligand-binding domain; 1.
DR Gene3D; 1.20.58.390; Neurotransmitter-gated ion-channel transmembrane domain; 1.
DR InterPro; IPR006202; Neur_chan_lig-bd.
DR InterPro; IPR036734; Neur_chan_lig-bd_sf.
DR InterPro; IPR006201; Neur_channel.
DR InterPro; IPR036719; Neuro-gated_channel_TM_sf.
DR InterPro; IPR038050; Neuro_actylchol_rec.
DR InterPro; IPR003582; ShKT_dom.
DR PANTHER; PTHR18945; NEUROTRANSMITTER GATED ION CHANNEL; 1.
DR PANTHER; PTHR18945:SF910; SHKT DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF02931; Neur_chan_LBD; 1.
DR Pfam; PF01549; ShK; 1.
DR SMART; SM00254; ShKT; 1.
DR SUPFAM; SSF90112; Neurotransmitter-gated ion-channel transmembrane pore; 1.
DR SUPFAM; SSF63712; Nicotinic receptor ligand binding domain-like; 1.
DR PROSITE; PS51670; SHKT; 1.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|PROSITE-ProRule:PRU01005};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Receptor {ECO:0000313|EMBL:KRY53100.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000054653};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 316..338
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 345..363
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 375..397
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 465..487
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 61..95
FT /note="ShKT"
FT /evidence="ECO:0000259|PROSITE:PS51670"
FT DISULFID 61..95
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01005"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:KRY53100.1"
SQ SEQUENCE 488 AA; 55855 MW; C3EE628927C718A1 CRC64;
LYLFKRLGEI QLFNYTKFYR EMFIPILILL FFTTLHSSTV DGQSILNPPK LYNPHSNSFN
CVDQSSKCSM WASRGECFAN PSWMIRNCPH SCEACQGGNR VWDLRNNIIS KYNSSTQIQK
FTVEMINIKA VSLKHIETDE QEQVLKIYGT LLMTWNDSRI QWNKTEWGIA WMNLVWSQIW
TPKLVALKSA PMDSSQFESD SLAVHHTGAV VNWVDFVLET YIQFDYSRYP YDQQSGCVRF
GDRRDFSIRF EVDQNAEQEL TRSLDKLRPV GWTVRSAQIR EGSNQEKILS LDMDDATDAF
APVVDLCVSL KRDNSYTFAL FFLPCAATAM ITVLSFWLSR QWNKIMLLVV SVGLQIFFLT
SLTNHLPPSN GRTPVIVKFC SCSMVITCIL ILAELIFGSL ETIRSALPPP RWLMITVNRV
NKFCPVVLGT ADRANKVVDD QHSDHIVDLG APPNTGSVWS PAVRILRFIL FLFVITFYVL
LLMATFMG
//
