ID A0A0V1D6S7_TRIBR Unreviewed; 2728 AA.
AC A0A0V1D6S7;
DT 16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT 16-MAR-2016, sequence version 1.
DT 22-FEB-2023, entry version 25.
DE SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:KRY57064.1};
GN Name=PCLO {ECO:0000313|EMBL:KRY57064.1};
GN ORFNames=T03_3711 {ECO:0000313|EMBL:KRY57064.1};
OS Trichinella britovi (Parasitic roundworm).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Enoplea; Dorylaimia;
OC Trichinellida; Trichinellidae; Trichinella.
OX NCBI_TaxID=45882 {ECO:0000313|EMBL:KRY57064.1, ECO:0000313|Proteomes:UP000054653};
RN [1] {ECO:0000313|EMBL:KRY57064.1, ECO:0000313|Proteomes:UP000054653}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ISS120 {ECO:0000313|EMBL:KRY57064.1};
RA Korhonen P.K., Edoardo P., Giuseppe L.R., Gasser R.B.;
RT "Evolution of Trichinella species and genotypes.";
RL Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KRY57064.1}.
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DR EMBL; JYDI01000035; KRY57064.1; -; Genomic_DNA.
DR Proteomes; UP000054653; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:InterPro.
DR GO; GO:0031267; F:small GTPase binding; IEA:InterPro.
DR GO; GO:0006887; P:exocytosis; IEA:InterPro.
DR CDD; cd00992; PDZ_signaling; 1.
DR Gene3D; 2.30.42.10; -; 1.
DR Gene3D; 2.60.40.150; C2 domain; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR000008; C2_dom.
DR InterPro; IPR035892; C2_domain_sf.
DR InterPro; IPR001478; PDZ.
DR InterPro; IPR036034; PDZ_sf.
DR InterPro; IPR039032; Rim-like.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR12157:SF21; RAB3 INTERACTING MOLECULE, ISOFORM F; 1.
DR PANTHER; PTHR12157; REGULATING SYNAPTIC MEMBRANE EXOCYTOSIS PROTEIN; 1.
DR Pfam; PF00168; C2; 1.
DR SMART; SM00239; C2; 1.
DR SMART; SM00228; PDZ; 1.
DR SUPFAM; SSF49562; C2 domain (Calcium/lipid-binding domain, CaLB); 1.
DR SUPFAM; SSF50156; PDZ domain-like; 1.
DR PROSITE; PS50004; C2; 1.
DR PROSITE; PS50106; PDZ; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000054653}.
FT DOMAIN 2340..2429
FT /note="PDZ"
FT /evidence="ECO:0000259|PROSITE:PS50106"
FT DOMAIN 2518..2644
FT /note="C2"
FT /evidence="ECO:0000259|PROSITE:PS50004"
FT REGION 152..213
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 234..452
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 651..687
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1070..1091
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1142..1163
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1357..1378
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1390..1413
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2250..2274
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 1708..1735
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 152..166
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 187..202
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 234..259
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 271..295
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 318..334
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 353..422
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1142..1162
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 2728 AA; 301330 MW; C1DE4FFC79CD5FD7 CRC64;
MKCGDSKHFR MFVCVLVRRL RAEVPGIRTG AVNKDAAHWL VRIDRFTNVY RLLEWEFDWL
PPFPPAGSVE AAVIERFILP RMFGKVFGGI THAVSHTASQ LRTQVLAPQF NATVDPLAGL
SEVERAHILA VQRRAADEDF KLSQQPMVLP RSTASTVDAT ASLPPPSLAP STLPSRPSSA
SSTETEGADD TSDDDDDDSG PIPDLDQIGL SEVTPADMRL DGLAEIGQER LLTSQESIEE
QPTIVVHSPS TNSNGAVDES DANELEREEE EDERQQQHAE EDSLDELEHY SSPESDTQDV
VEPVVQIPGD QENLQLAATG AGDESPSSSG DEWNCEYAGE SFTAPIRKSI EIDEPTTTPQ
SNERPIYQTE PAASSPPPAA DTTASSLFNY DQTDPTEWTN VEPLLQTQEI ELSSNETDQS
VMNKAPGVEM DEEASSQTFY GDESSNPFLD GASFADDQAI SELVPVEEPD EEVDEEKFNN
DNEQQLVIDA SADEQLSAAL AEPIPSSDDD TFGVDEKIIS QAEKTFATVA DHADSFGISN
IAAAASSVVI ERQTSRFLTE MTSRSVKQPF DMPAASQAKL QSANKIASAA LDGFGGKSLK
NFGGLFSRPK VDFSSFATSV KKSTEAALKK ATDSVASSFS SSSVVSMSQD SFNSNNQTCT
VPPKSPSSSA INADNASVNS NKSSDQWSAL EVDKADNNNN NNSSAVMKST AAAVVGKKGI
QPSPVVSNTF RVSCNSDSTE DTGYSSRCSP EDEFYRVGSD GAQFLITYDS SRKLGVDTVK
APLSPRRRIN PFIEDGIFSQ RLITSVIVEQ ADDQLTKSFH VSGQKRQLDI VEKVEPGEQE
KFHLIAEQSF WSSEPLQSQQ LFGEIDGPQE ISQAGKDSTP KIEEVETLPL PDESTPLKYP
PQQSIANSGA DEIAKLFAVE DSAPDSSACT QMYDSSEVSS EQFDEDAQKR ITEIESEFLL
QNNQSADSAE DWQMCPLCQM AEVHVRPDGV SINGQPCGNC GLTVCSKCGH VVEQNGYGYV
AYAIQILPKL MVAGIVMVMP DRDAYAFCVY WFRTKSQAIS EDDNSKLTFE KSQEVDSDIS
DQASDSSDSY PDVVIEVPSS PVKQLDFDQE FSTSNSKQCY KVFRDIEKHF MNNFDQCDDT
KHEGKVDHHD QQTGHSDKGN FETDPFKTVP ISVGQSPTFE KLTEQASPSD AQLSIGEEIF
GKIVPPEQSC PSTNSNNAQE DSIDYAQAMR YYNTQPFYIH RPGPVYTILE DDEEVMELNQ
DGKNKTAYMA AISASRPSTL SSSSSKSQLT SFSSPLANSY VGLDRPAQQM QTSSNASTEQ
LTSTVSSDVL VQHFFATSTT STTTTSITAS KSHALQSNST FTPKPVRIAP PPPPPSQYSI
SRDAKIEKSI HQETSNKPTG GRRHSADVPL STDVNDSVVS GSLNGTAFKP VHSSSSTWTI
LAGQKKSDTP SSSTVAVSFA LPVVRTIDMD ASDPSSCLPL YSAASTLCTT ATTAPATTPI
TTNEADDDEA VVECSGTGPF VSRLKRSPAM LLNCIKNETD LRAGSLQTAL QSTPTSALTA
CSSTSYPSSR LIDSAIPTPT KVVSSTSCGD TLQSGKTFLN ERLFFAQASP GEMGRRKLPN
IPKIASNRHQ QDVDEQLCNI SWSAGPVCSS TTTVNGSGIT GITGGSSYNN VISMPSSWKN
IGQTLRPQHS TPLATNCRRL LPPTLARVLL KQELREALTK RLDKLEAAEI EANQREFVVG
RYMATGVYPQ SAGVDSAPSV VRCGLSPEMV RGCVVHFDRS RYLSSIRQRE SSKAEFSNSY
GQSSRYGSYG GEEQWNSSRL VRKKESFVKK DDSVVLLFVK FCGSSSVQTK RNDFTVQTSD
VLERYKDAST QTVQQSSETT NSGNFVRFKP KDDLLLSKHK NVGVSTSEGP TCRTISTSTD
EIDEDRLMAR RRSEGNKKWR NLNSKSFTYF SADDDFASRE SRRSKIRREI ARRREKFSSY
EDLFNLPPHR ADSTYRYMDD GMELNNYLTP SLYSSSRFSG HYGSLPRIDR LYDYSPMSRN
ALYDDEPSSF SASYPLRPYQ KYDRLYRSDT APFVDGQDSA FHRGNYGTLT WRDQKPWFID
GQRSLSSSLP YLNNLYESLD SQPECSFRGY SRGRRFGEAG TEQVNTPRSS SMLSHYANYL
HNDFLRRSSA LDDGYGNLCE DRSTAKCMPY ADSSTEFNCR PSSVMEPIAS RLPYDKYDEP
LNDCLSLHRC RTDAPMETYP STRDYCSMTA QQPTFNSRRR RSRRQQDQEP LYSGVKSAQY
DADLKTQSYN PYLIDSSLQN ASVENHHRQR ASSQILLEEG KSTFRQASSP SSANIKRLLL
VRDVRDRSGH GIGMRVIGGK ILPGSDGELV AYVAAVYKGG LVDLMEEVKE GDQILEWNGI
KLTGKTYEEV QSIIDNTEGE FEIVLRSDAN LNQVYRLEEG PSSSLDKGYE SDCYLSNLAH
PRLAKLALQR KTGLDQTNDR HCQGLDFGKA SPCFSTTPRS RSPFTANQQQ NSLLAQDLAN
EGLLKLRVCF DHTSDTLFVT VLCAARLPNV DAKKRRPPNP FVKIYILPER IVQNKRRTKF
IARSNNPVWN QTVVYKDLNL EQALSKMLEF TVWSYDRFKQ NTFLGKVIIN LSAANRWKKH
DYTVIPFEVC ISMVKMQLFI HLIAALLFLF ARGEDDAVVE PTFADLKNLI DLYAREMEAM
NALGTSRRLK TIPLRDPRFI TRKLFKND
//
