ID A0A0V1D703_TRIBR Unreviewed; 582 AA.
AC A0A0V1D703;
DT 16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT 16-MAR-2016, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE SubName: Full=Bone morphogenetic protein 5 {ECO:0000313|EMBL:KRY57326.1};
DE Flags: Fragment;
GN Name=BMP5 {ECO:0000313|EMBL:KRY57326.1};
GN ORFNames=T03_3772 {ECO:0000313|EMBL:KRY57326.1};
OS Trichinella britovi (Parasitic roundworm).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Enoplea; Dorylaimia;
OC Trichinellida; Trichinellidae; Trichinella.
OX NCBI_TaxID=45882 {ECO:0000313|EMBL:KRY57326.1, ECO:0000313|Proteomes:UP000054653};
RN [1] {ECO:0000313|EMBL:KRY57326.1, ECO:0000313|Proteomes:UP000054653}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ISS120 {ECO:0000313|EMBL:KRY57326.1};
RA Korhonen P.K., Edoardo P., Giuseppe L.R., Gasser R.B.;
RT "Evolution of Trichinella species and genotypes.";
RL Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the TGF-beta family.
CC {ECO:0000256|ARBA:ARBA00006656, ECO:0000256|RuleBase:RU000354}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KRY57326.1}.
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DR EMBL; JYDI01000032; KRY57326.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0V1D703; -.
DR STRING; 45882.A0A0V1D703; -.
DR Proteomes; UP000054653; Unassembled WGS sequence.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-KW.
DR GO; GO:0071595; C:Nem1-Spo7 phosphatase complex; IEA:InterPro.
DR GO; GO:0008083; F:growth factor activity; IEA:UniProtKB-KW.
DR GO; GO:0035307; P:positive regulation of protein dephosphorylation; IEA:InterPro.
DR CDD; cd13761; TGF_beta_BMP5_like; 1.
DR Gene3D; 2.60.120.970; -; 1.
DR Gene3D; 2.10.90.10; Cystine-knot cytokines; 1.
DR InterPro; IPR029034; Cystine-knot_cytokine.
DR InterPro; IPR019168; NEP1-R1.
DR InterPro; IPR001839; TGF-b_C.
DR InterPro; IPR001111; TGF-b_propeptide.
DR InterPro; IPR015615; TGF-beta-rel.
DR InterPro; IPR017948; TGFb_CS.
DR PANTHER; PTHR11848:SF298; PROTEIN 60A-RELATED; 1.
DR PANTHER; PTHR11848; TGF-BETA FAMILY; 1.
DR Pfam; PF00019; TGF_beta; 1.
DR Pfam; PF00688; TGFb_propeptide; 1.
DR Pfam; PF09771; Tmemb_18A; 1.
DR PRINTS; PR00669; INHIBINA.
DR SMART; SM00204; TGFB; 1.
DR SUPFAM; SSF57501; Cystine-knot cytokines; 1.
DR PROSITE; PS00250; TGF_BETA_1; 1.
DR PROSITE; PS51362; TGF_BETA_2; 1.
PE 3: Inferred from homology;
KW Growth factor {ECO:0000256|ARBA:ARBA00023030,
KW ECO:0000256|RuleBase:RU000354}; Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000054653};
KW Secreted {ECO:0000256|ARBA:ARBA00022525};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 6..27
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 65..83
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 103..122
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 155..177
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 445..582
FT /note="TGF-beta family profile"
FT /evidence="ECO:0000259|PROSITE:PS51362"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:KRY57326.1"
SQ SEQUENCE 582 AA; 66663 MW; 5AABF27284BA913F CRC64;
LFILLLVYFS EAYFLILKCE NILIYIFKMH RVHLESDTCD DLKAFERRLM EIIACMQPAA
KKWRAILAVV LSCLVVSSCL WLADPHLSEE NLIDSLKRNT FFSASFIVMI ILLLCGIHRR
VVAPSIMAAR CRSVLAEFNL SCDDCKFIVH KMTTVLTLCC LSVVLSTVFG LALSNLANSF
KNNIASPVFY ADNGYDKTIA FPLFRNREMQ EFQTEILHFL GLNKPPNPSK ELRSPHSVFL
SQYMIDLYKS IQFEADDNED KFFYNSLPEK YSARFDVENA STAVTEWGVD LFDWSEADTI
ISFEDHQYEK QFMNYEVLLR YKFDIPEFPQ NYRLIGAELR LFSNASSVSR LIIGKNVKMV
IFRVDDKNEL HLVAEVMLNQ QLKGWTVVNV TSCLEEWISS PESNFGLAIS LLDTKGRYWS
VNDIGVADCF MVGYFSADNI NAHRRIKRDA FKTGGVSRNL NNDMDWSSVI GMDTKWTRSA
CQRRTLYVSF RDLGWQDWII APDGYAAYYC YGECSFPLNA HMNATNHAIV QTLAHLMNPG
RVPKPYCAPT KLSSISVLYF DDSSNVVLKK YNNMVVKTCG CH
//
