ID A0A0V1D966_TRIBR Unreviewed; 1043 AA.
AC A0A0V1D966;
DT 16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT 16-MAR-2016, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE SubName: Full=U4/U6 small nuclear ribonucleoprotein Prp3 {ECO:0000313|EMBL:KRY58113.1};
GN Name=PRPF3 {ECO:0000313|EMBL:KRY58113.1};
GN ORFNames=T03_13512 {ECO:0000313|EMBL:KRY58113.1};
OS Trichinella britovi (Parasitic roundworm).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Enoplea; Dorylaimia;
OC Trichinellida; Trichinellidae; Trichinella.
OX NCBI_TaxID=45882 {ECO:0000313|EMBL:KRY58113.1, ECO:0000313|Proteomes:UP000054653};
RN [1] {ECO:0000313|EMBL:KRY58113.1, ECO:0000313|Proteomes:UP000054653}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ISS120 {ECO:0000313|EMBL:KRY58113.1};
RA Korhonen P.K., Edoardo P., Giuseppe L.R., Gasser R.B.;
RT "Evolution of Trichinella species and genotypes.";
RL Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KRY58113.1}.
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DR EMBL; JYDI01000024; KRY58113.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0V1D966; -.
DR Proteomes; UP000054653; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0046540; C:U4/U6 x U5 tri-snRNP complex; IEA:InterPro.
DR GO; GO:0046873; F:metal ion transmembrane transporter activity; IEA:InterPro.
DR GO; GO:0000398; P:mRNA splicing, via spliceosome; IEA:InterPro.
DR InterPro; IPR013881; Pre-mRNA_splic_Prp3_dom.
DR InterPro; IPR027104; Prp3.
DR InterPro; IPR010541; Prp3_C.
DR InterPro; IPR003689; ZIP.
DR PANTHER; PTHR14212; U4/U6-ASSOCIATED RNA SPLICING FACTOR-RELATED; 1.
DR PANTHER; PTHR14212:SF0; U4_U6 SMALL NUCLEAR RIBONUCLEOPROTEIN PRP3; 1.
DR Pfam; PF08572; PRP3; 1.
DR Pfam; PF06544; Prp3_C; 1.
DR Pfam; PF02535; Zip; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW mRNA processing {ECO:0000256|ARBA:ARBA00022664};
KW mRNA splicing {ECO:0000256|ARBA:ARBA00023187};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000054653};
KW Ribonucleoprotein {ECO:0000313|EMBL:KRY58113.1};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 48..70
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 82..102
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 117..136
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 303..323
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 329..350
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 371..392
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 672..883
FT /note="Pre-mRNA-splicing factor 3"
FT /evidence="ECO:0000259|Pfam:PF08572"
FT DOMAIN 906..1027
FT /note="Small nuclear ribonucleoprotein Prp3 C-terminal"
FT /evidence="ECO:0000259|Pfam:PF06544"
FT REGION 479..512
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 479..497
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1043 AA; 117357 MW; 370115804EE31E44 CRC64;
MHPHRFDSTS KIVSNHSTHP DDLLTTNCWN CSTLPGGDVH QQHASWQIWT IGLAFITLIS
SCAAVGIVLL PLIGARRYKK ILNWFVGLGV GSLSGSAVFN LIPSAFEIDA TIGHTPLLLW
TLLAGIYGFC LVDNGIKMIS ERRKKVDNSS VRVLNVKPVT NEIMGSGVSL TSIDESKVST
GGVYTSNCSL VQVKPYPNQS SSPQHTYFDY GKELLSVATG LCSHDHPISS IGQKRHISSI
AWMVIFGDAI HNFIDGLSIG AAFSYNLFDG ISVSIAVFCE EFPHELGDVA ILISSGMTIR
QALFYNILSA LTCYIGFVIG VILGEIPHAS MYIYSLAGGM FMFISLANML PDMNKKVEDK
LKHDFMSGFK LFFIQFSGIV FGLLCMFTLA MVENFVTLDG FSVKMPESEP KEAAKIILKK
AIGTTHSKLT HALTKAIDRG YDKTKMKQKL LEVHSEEEDV EKILNAVFSE SSQLIKPSGR
KSRFDRVDDE KSSEIKTSDN LDSVASAASE KPALENSKVQ EIMLKAQRMI EERKKVLQVN
SFPYVVNFEY ENSLNSRICQ LQPSKIAPDQ AKEFMNASLL RVNRMAELRQ SIANKLPALM
NYQAVARQPG KPTPLILDSE GRTVDTDGRA VQLIQRQPTL KANIRAEKVA LFNKAVQETA
QATDDRVTEN ATFFDKRVKV KGPGRARREF SFKQDGEYVK QANRLRAKCR LERLQQEISL
ASKKTGISSA VKLAMVVPRV AESVEAEVPN VEWWDSVILP GETYDVDLDS LNFDIITNLI
EHPVQLKPPG EHSDRNCLKV YLTKKEQKKL RRQNRKETQR EKTEKIRLGL EPPPEPKVKI
SNLMRVLESQ AIQDPTKMEA HVREQMAKRL KKHEEANLAR KLTHEQRIMK RAKKISDDLS
TGVHVAVYRV LDLSDPAKKF KVEMNAKQIH MTGTVVLHKD INVIVVEGGP KQQRFFKRLM
MHRIKWEDQQ IPGTSKKQSP PNRCFLIWEG IVKKKAFGEI KFKMCPLEKL AREYFQKHGV
EYYWDMAYSR AIMEQNDAES TTA
//
