ID A0A0V1DB84_TRIBR Unreviewed; 1112 AA.
AC A0A0V1DB84;
DT 16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT 16-MAR-2016, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE SubName: Full=Cullin-2 {ECO:0000313|EMBL:KRY58582.1};
DE Flags: Fragment;
GN Name=cul-2 {ECO:0000313|EMBL:KRY58582.1};
GN ORFNames=T03_4177 {ECO:0000313|EMBL:KRY58582.1};
OS Trichinella britovi (Parasitic roundworm).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Enoplea; Dorylaimia;
OC Trichinellida; Trichinellidae; Trichinella.
OX NCBI_TaxID=45882 {ECO:0000313|EMBL:KRY58582.1, ECO:0000313|Proteomes:UP000054653};
RN [1] {ECO:0000313|EMBL:KRY58582.1, ECO:0000313|Proteomes:UP000054653}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ISS120 {ECO:0000313|EMBL:KRY58582.1};
RA Korhonen P.K., Edoardo P., Giuseppe L.R., Gasser R.B.;
RT "Evolution of Trichinella species and genotypes.";
RL Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the cullin family.
CC {ECO:0000256|ARBA:ARBA00006019, ECO:0000256|PROSITE-ProRule:PRU00330,
CC ECO:0000256|RuleBase:RU003829}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KRY58582.1}.
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DR EMBL; JYDI01000020; KRY58582.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0V1DB84; -.
DR Proteomes; UP000054653; Unassembled WGS sequence.
DR GO; GO:0031625; F:ubiquitin protein ligase binding; IEA:InterPro.
DR GO; GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
DR Gene3D; 1.20.1310.10; Cullin Repeats; 4.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR045093; Cullin.
DR InterPro; IPR016158; Cullin_homology.
DR InterPro; IPR036317; Cullin_homology_sf.
DR InterPro; IPR001373; Cullin_N.
DR InterPro; IPR019559; Cullin_neddylation_domain.
DR InterPro; IPR016159; Cullin_repeat-like_dom_sf.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR11932; CULLIN; 1.
DR PANTHER; PTHR11932:SF177; CULLIN-2; 1.
DR Pfam; PF00888; Cullin; 1.
DR Pfam; PF10557; Cullin_Nedd8; 1.
DR SMART; SM00182; CULLIN; 1.
DR SMART; SM00884; Cullin_Nedd8; 1.
DR SUPFAM; SSF75632; Cullin homology domain; 1.
DR SUPFAM; SSF74788; Cullin repeat-like; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS50069; CULLIN_2; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000054653}.
FT DOMAIN 361..588
FT /note="Cullin family profile"
FT /evidence="ECO:0000259|PROSITE:PS50069"
FT REGION 821..852
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 833..852
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:KRY58582.1"
SQ SEQUENCE 1112 AA; 127654 MW; 3404856CCA6FB7F2 CRC64;
LTLILYGINY ALAWSKLLPF SQFLHPYGTK LCLPTLYSRP GKPHYAFIQG GADVSTSARE
IVIRCMFCTN NTEISNCCED HLLEKYFERW RKYHAGAKYL DRLFHYLNAQ YVNKLKITDS
DLFYGRLFRE ENQVNTKFVG ELAMDVWNEK MVRPLTDRLV ALLLKEIKRY RNGVPVNTDV
LSGVIHSFND SENDDSGPAS EANTSEYYVD IAVLEKIRQE EARSERILHR SGVDKVQQIC
QEVLVNRHMS MFKSVAKEIV REENLADLSN MYALLSAKSS DLSFLVNEFE SYVRGIGQHC
MQNLKGDDVA QQFVEEILAV FDKYGQIVKK TFKGDHEFSA ALDRACLAVI NHRNGSKDPA
KAAEWLSKHI DQILRKSTKP IVDSCIDFEL TKAINILRFV DDKDLFHKYY SRSLANRLIS
GLSISIPAEE TMIHKLKSCC GYEFISKFQR MLSDITLSKE LTNNFVNYLQ ERVLGINVHM
MVLQAGAWPL MQCQLKIPIP PVIENAINEF EQYYTRFFSG RKLSWMLQFS VVDVMLHYLH
RRLMASVNLH QLAILLCFEN HDQLALEDLK IRSGIQDGGF DSNLQCLIDA GILLRQSEKY
DGQLRTKIIL NKHLTSRRVK FRVNSPFFSD AFNKDLSAGR QVHADLKVDR KLFIECTLVR
IMKSRKLIKH EDLLREVMEQ CVGRFVPEAE CVQNRQPEHR MEDIHCCVIG VQIKVDRPTF
GLYYPARTFI QTPLEKWHLL AVDNTICNQS EHRIRMRCLS VLLVTMFVSS KVQAHGIFDW
LNFGQAGLSP VPLSTSGQVV DYARQGVNFL SFLKSLKPLT TSRRRAERRK HRQRAKPLSE
QAPDDETDLH TDDHRPLLLT SRRRANMPLY KAAPTLAESA QNFPGFGACL PNGTPFFNHI
SPSILQNMLR IFPGAQNFMR KMLPATRVHP KKLMGKWYWV LMTPAALSRH CATSDYHGLV
LSRNGTGTFA TFDSFRDGSS YGLPKFGFGY GVISNDNQAL VYMQSDPCPY QVVYTSSDYD
EDDYNTETQY NYVVLSNWAR YPVIALAKNV EQFMMSDFEQ LKNDLNRDGL HNKVTELLKS
TELADWSVCE AKQTLKQMAT QLIQNLLSKS SL
//
