ID A0A0V1H445_9BILA Unreviewed; 296 AA.
AC A0A0V1H445;
DT 16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT 16-MAR-2016, sequence version 1.
DT 24-JAN-2024, entry version 22.
DE SubName: Full=Gremlin-1 {ECO:0000313|EMBL:KRZ05358.1};
GN Name=GREM1 {ECO:0000313|EMBL:KRZ05358.1};
GN ORFNames=T11_5862 {ECO:0000313|EMBL:KRZ05358.1};
OS Trichinella zimbabwensis.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Enoplea; Dorylaimia;
OC Trichinellida; Trichinellidae; Trichinella.
OX NCBI_TaxID=268475 {ECO:0000313|EMBL:KRZ05358.1, ECO:0000313|Proteomes:UP000055024};
RN [1] {ECO:0000313|EMBL:KRZ05358.1, ECO:0000313|Proteomes:UP000055024}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ISS1029 {ECO:0000313|EMBL:KRZ05358.1};
RA Korhonen P.K., Edoardo P., Giuseppe L.R., Gasser R.B.;
RT "Evolution of Trichinella species and genotypes.";
RL Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000256|ARBA:ARBA00004613}.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00039}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KRZ05358.1}.
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DR EMBL; JYDP01000141; KRZ05358.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0V1H445; -.
DR STRING; 268475.A0A0V1H445; -.
DR Proteomes; UP000055024; Unassembled WGS sequence.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR Gene3D; 2.10.90.10; Cystine-knot cytokines; 1.
DR InterPro; IPR006207; Cys_knot_C.
DR InterPro; IPR029034; Cystine-knot_cytokine.
DR InterPro; IPR004133; DAN.
DR PANTHER; PTHR15283:SF4; BURSICON; 1.
DR PANTHER; PTHR15283; GREMLIN 1; 1.
DR Pfam; PF03045; DAN; 1.
DR SMART; SM00041; CT; 1.
DR PROSITE; PS01225; CTCK_2; 1.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW Reference proteome {ECO:0000313|Proteomes:UP000055024}.
FT DOMAIN 198..289
FT /note="CTCK"
FT /evidence="ECO:0000259|PROSITE:PS01225"
FT REGION 116..180
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 122..151
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 152..168
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 296 AA; 34145 MW; FCBBE25A19FF11BD CRC64;
MDEKRTVDEE ALLTRHTDEE CNDRASHDFY EILRTQATLR PTVVLPLYLL LILSCVETIR
AGPPPLNSST FRDLSRMAFR ALSGADYEDT AVGLVRPGHF GHQWHSTMMN NTSFVSNESS
DRLVGSRRDR HRHLGSDGRR RNPESNKSKL WSKKSRQRSN KHHHQQRQQQ QQRQQQLYPN
KRQAYIIASR DVIRTDYCRT IAFKQRIRIE GCLSKTVINS FCYGQCNSFY IPRLHGARLM
ASFKSCSVCQ PSQITSITVT LHCPGRLGSV HRRKYLKVKQ CACMSVEQPI KPTLSI
//
