ID A0A0V1H7I2_9BILA Unreviewed; 627 AA.
AC A0A0V1H7I2;
DT 16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT 16-MAR-2016, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE SubName: Full=Kelch-like protein 3 {ECO:0000313|EMBL:KRZ06384.1};
GN Name=KLHL3 {ECO:0000313|EMBL:KRZ06384.1};
GN ORFNames=T11_14280 {ECO:0000313|EMBL:KRZ06384.1};
OS Trichinella zimbabwensis.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Enoplea; Dorylaimia;
OC Trichinellida; Trichinellidae; Trichinella.
OX NCBI_TaxID=268475 {ECO:0000313|EMBL:KRZ06384.1, ECO:0000313|Proteomes:UP000055024};
RN [1] {ECO:0000313|EMBL:KRZ06384.1, ECO:0000313|Proteomes:UP000055024}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ISS1029 {ECO:0000313|EMBL:KRZ06384.1};
RA Korhonen P.K., Edoardo P., Giuseppe L.R., Gasser R.B.;
RT "Evolution of Trichinella species and genotypes.";
RL Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Probable substrate-specific adapter of an E3 ubiquitin-
CC protein ligase complex which mediates the ubiquitination and subsequent
CC proteasomal degradation of target proteins. May have a role in synapse
CC differentiation and growth. {ECO:0000256|ARBA:ARBA00043912}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KRZ06384.1}.
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DR EMBL; JYDP01000119; KRZ06384.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0V1H7I2; -.
DR UniPathway; UPA00143; -.
DR Proteomes; UP000055024; Unassembled WGS sequence.
DR GO; GO:0016567; P:protein ubiquitination; IEA:UniProtKB-UniPathway.
DR Gene3D; 1.25.40.420; -; 1.
DR Gene3D; 2.120.10.80; Kelch-type beta propeller; 1.
DR InterPro; IPR011705; BACK.
DR InterPro; IPR017096; BTB-kelch_protein.
DR InterPro; IPR000210; BTB/POZ_dom.
DR InterPro; IPR015915; Kelch-typ_b-propeller.
DR InterPro; IPR006652; Kelch_1.
DR InterPro; IPR011333; SKP1/BTB/POZ_sf.
DR PANTHER; PTHR24412:SF35; ACTIN-BINDING PROTEIN IPP; 1.
DR PANTHER; PTHR24412; KELCH PROTEIN; 1.
DR Pfam; PF07707; BACK; 1.
DR Pfam; PF00651; BTB; 1.
DR Pfam; PF01344; Kelch_1; 5.
DR PIRSF; PIRSF037037; Kelch-like_protein_gigaxonin; 1.
DR SMART; SM00875; BACK; 1.
DR SMART; SM00225; BTB; 1.
DR SMART; SM00612; Kelch; 6.
DR SUPFAM; SSF117281; Kelch motif; 2.
DR SUPFAM; SSF54695; POZ domain; 1.
DR PROSITE; PS50097; BTB; 1.
PE 4: Predicted;
KW Kelch repeat {ECO:0000256|ARBA:ARBA00022441};
KW Reference proteome {ECO:0000313|Proteomes:UP000055024};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 57..140
FT /note="BTB"
FT /evidence="ECO:0000259|PROSITE:PS50097"
SQ SEQUENCE 627 AA; 69656 MW; F08DBFBEE51CE3C4 CRC64;
MKKSMINLNA QRTDDQTEDE IASEVEFARD SAVFRSLSHW INFKHNLTSL RDEKALCDVV
LVASHLKTDS NEGSSSSNSA EVEIPAHRII LASACPYFKA MFQSNMSEVG QGKIRIHGVE
PDALKSLVNF MYTSEIAITA ENVQYILIAS DLLEMSEVTN SCCEFLKSQL NPSNCIGIQE
FAEHHSCISL SIFARVYCEQ HFDEVIKYEE YLSLSLENML QIISSDNLMT RCESDVCEAV
MKWTRHDLKK RQAYLPKLFQ CIRLPLLPIP YLFDVVEKDE LVKASMPCKD LIIGALKHHL
LFENLSSCNA RPRGLCASTD SALGIIVIGG QVPRAVSNVD IFYISNYTWN SLNPMPNRRC
RFGIASADDR IYVIGGFNGT TRVRYVEYFD SMRGCWYTAP SLLAKRSTLG AAAIDDVIYA
VGGFDGLSGL NSAEMLDRRT GKWEFIAPMS TRRSSVGVVA YKGLLYAVGG FDGGHKTCLK
SVERYDPRIN RWQTVESMEF RRSGPGVVVY DGRLFAMGGH DGPSVLNSVE VYDANGGGWQ
MLPCQMETCR RNFGACVADH SLYLVGGDDG YSTLSSVEIY NVHVGSWSTL PTNMPLGRSY
AGVAVAKRSC FPLLSVPDLF VIQSAEV
//
