ID A0A0V1HA05_9BILA Unreviewed; 1799 AA.
AC A0A0V1HA05;
DT 16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT 16-MAR-2016, sequence version 1.
DT 27-MAR-2024, entry version 30.
DE RecName: Full=Structural maintenance of chromosomes protein 3 {ECO:0000256|ARBA:ARBA00018690};
DE AltName: Full=Complex I-49kD {ECO:0000256|ARBA:ARBA00030505};
DE AltName: Full=NADH-ubiquinone oxidoreductase 49 kDa subunit {ECO:0000256|ARBA:ARBA00031562};
GN Name=smc3 {ECO:0000313|EMBL:KRZ07103.1};
GN ORFNames=T11_1253 {ECO:0000313|EMBL:KRZ07103.1};
OS Trichinella zimbabwensis.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Enoplea; Dorylaimia;
OC Trichinellida; Trichinellidae; Trichinella.
OX NCBI_TaxID=268475 {ECO:0000313|EMBL:KRZ07103.1, ECO:0000313|Proteomes:UP000055024};
RN [1] {ECO:0000313|EMBL:KRZ07103.1, ECO:0000313|Proteomes:UP000055024}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ISS1029 {ECO:0000313|EMBL:KRZ07103.1};
RA Korhonen P.K., Edoardo P., Giuseppe L.R., Gasser R.B.;
RT "Evolution of Trichinella species and genotypes.";
RL Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=[4Fe-4S] cluster; Xref=ChEBI:CHEBI:49883;
CC Evidence={ECO:0000256|ARBA:ARBA00001966};
CC -!- SIMILARITY: Belongs to the SMC family. SMC3 subfamily.
CC {ECO:0000256|ARBA:ARBA00005917}.
CC -!- SIMILARITY: Belongs to the complex I 49 kDa subunit family.
CC {ECO:0000256|ARBA:ARBA00005769, ECO:0000256|RuleBase:RU003685}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KRZ07103.1}.
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DR EMBL; JYDP01000107; KRZ07103.1; -; Genomic_DNA.
DR Proteomes; UP000055024; Unassembled WGS sequence.
DR GO; GO:0005694; C:chromosome; IEA:InterPro.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0051287; F:NAD binding; IEA:InterPro.
DR GO; GO:0016651; F:oxidoreductase activity, acting on NAD(P)H; IEA:InterPro.
DR GO; GO:0048038; F:quinone binding; IEA:InterPro.
DR GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR GO; GO:0051276; P:chromosome organization; IEA:InterPro.
DR CDD; cd03272; ABC_SMC3_euk; 1.
DR Gene3D; 1.20.1060.20; -; 1.
DR Gene3D; 3.30.70.1620; -; 1.
DR Gene3D; 1.10.645.10; Cytochrome-c3 Hydrogenase, chain B; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR HAMAP; MF_01358; NDH1_NuoD; 1.
DR InterPro; IPR001135; NADH_Q_OxRdtase_suD.
DR InterPro; IPR014029; NADH_UbQ_OxRdtase_49kDa_CS.
DR InterPro; IPR022885; NDH1_su_D/H.
DR InterPro; IPR029014; NiFe-Hase_large.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR003395; RecF/RecN/SMC_N.
DR InterPro; IPR041741; SMC3_ABC_euk.
DR InterPro; IPR010935; SMC_hinge.
DR InterPro; IPR036277; SMC_hinge_sf.
DR NCBIfam; TIGR01962; NuoD; 1.
DR PANTHER; PTHR43977; STRUCTURAL MAINTENANCE OF CHROMOSOMES PROTEIN 3; 1.
DR PANTHER; PTHR43977:SF1; STRUCTURAL MAINTENANCE OF CHROMOSOMES PROTEIN 3; 1.
DR Pfam; PF00346; Complex1_49kDa; 1.
DR Pfam; PF06470; SMC_hinge; 1.
DR Pfam; PF02463; SMC_N; 1.
DR SMART; SM00968; SMC_hinge; 1.
DR SUPFAM; SSF56762; HydB/Nqo4-like; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR SUPFAM; SSF75553; Smc hinge domain; 1.
DR PROSITE; PS00535; COMPLEX1_49K; 1.
PE 3: Inferred from homology;
KW Cell cycle {ECO:0000256|ARBA:ARBA00022776};
KW Cell division {ECO:0000256|ARBA:ARBA00022618};
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Mitosis {ECO:0000256|ARBA:ARBA00022776};
KW NAD {ECO:0000256|ARBA:ARBA00023027, ECO:0000256|RuleBase:RU003685};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000055024};
KW Translocase {ECO:0000256|ARBA:ARBA00022967, ECO:0000256|RuleBase:RU003685};
KW Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|RuleBase:RU003685}.
FT DOMAIN 1012..1125
FT /note="SMC hinge"
FT /evidence="ECO:0000259|SMART:SM00968"
FT COILED 671..853
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 881..953
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1157..1334
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1361..1395
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1443..1470
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 1799 AA; 210182 MW; 2A9F8B8D4F0924B3 CRC64;
MSVSRFCKNI STRQMQRVMR ILSPVNCEQR RSYAGPVWYP DGKFYKRFNK VYFEPETVSD
SFRPSEADLA RARVLDDDRR PNLMPDLVER KVENMILNFG PQHPAAHGVL RLMLELDAEI
ILRAVPHIGL LHRATEKLIE YKTYTQALPY FDRLDYVSMM CNEHAFSLAV EKLLAVEVPP
RAKWIRVLFA ELTRILNHIL GITTHALDIG AMTPLFWLFE EREKLMEFYE RSSGARMHAN
YIRPGGVALD IPLGLLDDIH KWASEFSVRL DEVEDVLTES RMWKQRTIDI GVVTAENALN
WGFSGVMLRG SGIKWDIRKT EPYEVYDQIE FDVPIGTKGD CYDRYLVRME EMRQSLRIID
QCLNRMPAGE VKVDDHKLVP PKRSEMKRSM ESLIHHFKFF TEGYAVPPGC TYVPTEAPKG
EFGVYIVSDG SSKPYRCYIR APGFAHLSMI ESISKYHFIA DLVAILGTLD VVFGECMQCF
PAVVIKTNSN VYKTGFRSYR DQTIVEPFSS KHNVIVGRNG SGKSNFFYAI QFVLSDEFSH
LRVEQRQSLL HEGTGPRVLQ AFVEIVFDNS DSRLPFEKDE VRLRRLIGPK KDQYFLEGKM
IPKQEVQSLL ESAGFSKSNP YYIVKQGKIN ELATAPDSYR LKLLREVAGT RVYDERKEES
NVLLRDSKAR VEKIIEVLKY IEERLKTLEE ETQELKEYQK LDRMRRALEF TIFDHELADI
RRKLDLLAEK RENYNEGSNQ LHDTLQQATD QIYKQLRELE RQWSGFEEER LQMISEQSER
FKEKTKLELA IRDLKEEVEG ERSNRRKAEN ELDRLKAEIA EKQANLDQVQ PRFNELIKQE
QQVNTELAIA EQRQRELYSK QGWTEQFRSA EERDQWIKRN LAKITRQISD KRDQIVRLKS
ELEQELTRLD NVEVRLVEST QELEQQRESI ERNKRHQNEL KHNRDALQNE RQELWRTESG
LSQSLQACKE EINHMDMILR SIVPKAIIYG MDSVKKVIES LRSRHAHSNL VDGYYGMLIE
NFQTDKRFYT AVEMTAGNKL FYHIVENDRI GTKILEEINR QRLPGEVNFF PLNRIQYRQH
GYPQNQYVLP MINQLQFEER FLPVMQHCFG KTLICRNMDV ATQMARSERM DCITLEGDRV
SSRGALTGGF CDVRRSRLQL QSQRWNLKQQ AEELEAQLHS QREQLTIIEG KINGVSSEMQ
KLETKTGKMI DVYEKLQQDG RLLREERQML QQSKHPKERQ LSSLESTLQQ LEAQKESLNR
DLGSEMLSQL TADEQFSLEE LNRRILQLKE SAKVLFNERS ELETEKNRLE NQLQKNLLRK
KEELQLRLQE ISMADRTQSL DSHQSELLIV TQRITEISRR MGELEHQLEE YYIGKKKLNQ
QLEMCQNQER EVQAKITEDA KEMEKMANKQ SMLLRKKEDT MKKIRELGSL PSDAFDKYHN
LSSKQLFKQL EQCNNELKKY ENVNKKALDQ FVSFSEQKEK LLKRKDEVDG NLESIMDMIS
QLDQKKYDAI QLTFKLVSKY FEEVFHELVP TGRGHLVMKT MEMNGDNAVD LASIPQVEQF
TGVGIKVAFS GADETKEMQQ LSGGQKSLVA LALIFAIQKC DPAPFYLFDE IDAALDARHR
KSVAVKKKNS RSECGCSEFG ILTDCFFCFV PTRTLDVMDM NSDSFLLASL RCMYNKNFIT
FLNSFIKLLK TMELLQQFWK RSIVSGDIVD KSLALMEGFY DVRKRKNDVM KKLDECGSLP
WVAIFQYHYH SSLQLFKQLE QCNNELKKWE NVNKEALGQF LSAFQSQKRE AADVETTKF
//
