ID A0A0V1HB73_9BILA Unreviewed; 852 AA.
AC A0A0V1HB73;
DT 16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT 16-MAR-2016, sequence version 1.
DT 27-MAR-2024, entry version 17.
DE SubName: Full=Neurogenic locus notch-like protein 3 {ECO:0000313|EMBL:KRZ07689.1};
GN Name=Notch3 {ECO:0000313|EMBL:KRZ07689.1};
GN ORFNames=T11_15617 {ECO:0000313|EMBL:KRZ07689.1};
OS Trichinella zimbabwensis.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Enoplea; Dorylaimia;
OC Trichinellida; Trichinellidae; Trichinella.
OX NCBI_TaxID=268475 {ECO:0000313|EMBL:KRZ07689.1, ECO:0000313|Proteomes:UP000055024};
RN [1] {ECO:0000313|EMBL:KRZ07689.1, ECO:0000313|Proteomes:UP000055024}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ISS1029 {ECO:0000313|EMBL:KRZ07689.1};
RA Korhonen P.K., Edoardo P., Giuseppe L.R., Gasser R.B.;
RT "Evolution of Trichinella species and genotypes.";
RL Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00076}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KRZ07689.1}.
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DR EMBL; JYDP01000098; KRZ07689.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0V1HB73; -.
DR STRING; 268475.A0A0V1HB73; -.
DR Proteomes; UP000055024; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR CDD; cd00054; EGF_CA; 4.
DR Gene3D; 2.10.25.10; Laminin; 9.
DR InterPro; IPR001881; EGF-like_Ca-bd_dom.
DR InterPro; IPR013032; EGF-like_CS.
DR InterPro; IPR000742; EGF-like_dom.
DR InterPro; IPR009030; Growth_fac_rcpt_cys_sf.
DR PANTHER; PTHR24033; EGF-LIKE DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR24033:SF151; PROTEIN EYES SHUT; 1.
DR Pfam; PF00008; EGF; 2.
DR Pfam; PF12661; hEGF; 3.
DR SMART; SM00181; EGF; 11.
DR SMART; SM00179; EGF_CA; 7.
DR SUPFAM; SSF57196; EGF/Laminin; 5.
DR SUPFAM; SSF57184; Growth factor receptor domain; 1.
DR PROSITE; PS00022; EGF_1; 12.
DR PROSITE; PS01186; EGF_2; 9.
DR PROSITE; PS50026; EGF_3; 11.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157, ECO:0000256|PROSITE-
KW ProRule:PRU00076};
KW EGF-like domain {ECO:0000256|ARBA:ARBA00022536, ECO:0000256|PROSITE-
KW ProRule:PRU00076}; Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000055024};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}; Signal {ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..35
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 36..852
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5006879004"
FT TRANSMEM 773..799
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 262..298
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 306..343
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 345..382
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 384..422
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 467..505
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 508..545
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 547..583
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 585..621
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 623..659
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 661..701
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 703..739
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DISULFID 288..297
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 333..342
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 372..381
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 412..421
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 495..504
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 535..544
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 573..582
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 611..620
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 649..658
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 672..689
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 691..700
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 729..738
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
SQ SEQUENCE 852 AA; 95293 MW; 9941896D9762AA9C CRC64;
MVCSAVLVHF SRARTMENFS KIVALLCLVL HLTSSELFGS CPNGVREGVY DSTNNRCLIM
VEINLVDVEP NWFESATNSC TTKYPDSKLF SWFNERGQIA MIKDVIFKLS GNRTEFTVLN
GLYIADLVNN EYDSTLSWEF SNITDTMEEQ LYIMYNTTHQ YEWEYETKLP LATKDIYDIY
HLFYSTPICM VHKINVNKTE FSEKAIPVEC YNITAIGVKA LCSITYDGPQ TVNLCDEGFQ
GVFCNETIKN TSTTEFPPLY NISEACANLN CSDHGVCVET DGNYTCKCYP GYTGENCEKE
HRRFVNPLGC LNGPFCGKNG DCYQSGDDWK CACHPGFTGI RCEESIDLCD IYNPCLNNGK
CTTVNGQLRC KCNKYHVGEF CDFNVDQCIN TTINCGKAGR CVRLNNIEKC WCNAGFTGKE
CEEKVDLCDE NNMCNYANQC STVHEETHSY MQCKCNDWES GKYCTQRRSI CNIKGPCLSR
GVCGLLDDDS YVCHCKQGYH GKFCEIERIH ACDNNSTCGE YGKCIRLGND FLCQCNFGFT
GKYCETKLNS CEFKPCGLNG KCNRKDDGYE CICDPGYTGY FCENTIDMCY TLNPCRRGRC
ISRINGFQCI CPEGYMGMAC EQKYESCNSD LCLNGGTCYM VGEELRCHCQ PGYKGANCAR
KNDICKKHKN ICGSNGRCVY DETDGQISCS CNIGYDGKYC EKKVASCFNG NPCRPGNCTL
GEKSFNCQCP PDVTGELCAI GKTAVDDTDT DTFDDEDILD DEVDERIKSG NKYFALLAIA
YGMAIMGWIV AIVMMVLYYK NKKTGLPTTV DSITASVSNG ANVETVLCRQ IALNLPTMLG
SLLLGNAVLE YL
//
