ID A0A0V1HBA4_9BILA Unreviewed; 710 AA.
AC A0A0V1HBA4;
DT 16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT 16-MAR-2016, sequence version 1.
DT 27-MAR-2024, entry version 18.
DE SubName: Full=Protocadherin Fat 1 {ECO:0000313|EMBL:KRZ07819.1};
GN Name=FAT1 {ECO:0000313|EMBL:KRZ07819.1};
GN ORFNames=T11_5094 {ECO:0000313|EMBL:KRZ07819.1};
OS Trichinella zimbabwensis.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Enoplea; Dorylaimia;
OC Trichinellida; Trichinellidae; Trichinella.
OX NCBI_TaxID=268475 {ECO:0000313|EMBL:KRZ07819.1, ECO:0000313|Proteomes:UP000055024};
RN [1] {ECO:0000313|EMBL:KRZ07819.1, ECO:0000313|Proteomes:UP000055024}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ISS1029 {ECO:0000313|EMBL:KRZ07819.1};
RA Korhonen P.K., Edoardo P., Giuseppe L.R., Gasser R.B.;
RT "Evolution of Trichinella species and genotypes.";
RL Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00076}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KRZ07819.1}.
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DR EMBL; JYDP01000096; KRZ07819.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0V1HBA4; -.
DR Proteomes; UP000055024; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR CDD; cd00054; EGF_CA; 2.
DR Gene3D; 2.10.25.10; Laminin; 3.
DR InterPro; IPR001881; EGF-like_Ca-bd_dom.
DR InterPro; IPR000742; EGF-like_dom.
DR InterPro; IPR000152; EGF-type_Asp/Asn_hydroxyl_site.
DR PANTHER; PTHR24049; CRUMBS FAMILY MEMBER; 1.
DR PANTHER; PTHR24049:SF30; DELTA-LIKE PROTEIN; 1.
DR Pfam; PF00008; EGF; 1.
DR SMART; SM00181; EGF; 3.
DR SMART; SM00179; EGF_CA; 2.
DR SUPFAM; SSF57196; EGF/Laminin; 3.
DR PROSITE; PS00010; ASX_HYDROXYL; 1.
DR PROSITE; PS00022; EGF_1; 3.
DR PROSITE; PS01186; EGF_2; 1.
DR PROSITE; PS50026; EGF_3; 3.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157, ECO:0000256|PROSITE-
KW ProRule:PRU00076};
KW EGF-like domain {ECO:0000256|ARBA:ARBA00022536, ECO:0000256|PROSITE-
KW ProRule:PRU00076}; Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000055024};
KW Signal {ECO:0000256|SAM:SignalP}; Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..25
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 26..710
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5006879002"
FT TRANSMEM 518..543
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 386..423
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 425..462
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 464..501
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT REGION 569..710
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 580..646
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 654..710
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT DISULFID 413..422
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 452..461
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 491..500
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
SQ SEQUENCE 710 AA; 80097 MW; FBE6F61EF4BC8A4C CRC64;
MKMSRNKVLL FVSMIWLLIS GTADGSCPVS STAKNFGGKL LEEGGCLTVV DISEPQKLYG
KITLDHLHRF CMESFKGGRL LSFTDSQKLQ ILAGVNFKKD PTSTILLHPG IRVFKTNITT
KQDVFVEKCM QMETLNCMGY PYEYISTRNE KTAGMLYQCA EKKCCSNSDC DDTASLLTFE
SELLENISDL SADAYCRCIL FNPTSLNWNL SNERLYPCDD MKCDVFVCEN DEYRDCKETR
VKNCSYSSEA QGCKEFTYQV ISEKELPYGN DCENRNYGES CVCPCGGTWT QWSIVSGTCG
KVVSIRYRPR LDMVATNRSC DDAEDSCCKE TKEDFVICSQ YTYSKAEYKK FKAECEQHNG
VVNASEAELV CVCFDDRQFG TFCENTFDAC SEQKWCQNGG SCRNYKGSYR CDCMDNYSGE
NCTDIIKTCL SNAECMNGGI CALLHSGKAC KCTEGFVGAN CELKIGKCKA HVCMNGASCL
QVNNNTYKCD CSYKYEGTFC EEELSITEIL IRFVKGNLTL HLVVIIIMLI LVVICCISSL
QIISAHRILQ KRMYDKLFGR AKRLRQKALD EHAAKQKTHP EELNSQSLSS SSVGQQGKST
ERPPRKSVSK SQPLNKSQVM SSASQAARGS RKISTSKKTF ASARKTTMLQ KLMGKKSRSR
RSRSRSRSRS RRHSLRSRSR SRSRQSSRYR QSSRSRSRSR SRSHSRSRRS
//
