ID A0A0V1HH53_9BILA Unreviewed; 834 AA.
AC A0A0V1HH53;
DT 16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT 16-MAR-2016, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE RecName: Full=phospholipase A2 {ECO:0000256|ARBA:ARBA00013278};
DE EC=3.1.1.4 {ECO:0000256|ARBA:ARBA00013278};
DE Flags: Fragment;
GN Name=Pla2g6 {ECO:0000313|EMBL:KRZ10158.1};
GN ORFNames=T11_7574 {ECO:0000313|EMBL:KRZ10158.1};
OS Trichinella zimbabwensis.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Enoplea; Dorylaimia;
OC Trichinellida; Trichinellidae; Trichinella.
OX NCBI_TaxID=268475 {ECO:0000313|EMBL:KRZ10158.1, ECO:0000313|Proteomes:UP000055024};
RN [1] {ECO:0000313|EMBL:KRZ10158.1, ECO:0000313|Proteomes:UP000055024}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ISS1029 {ECO:0000313|EMBL:KRZ10158.1};
RA Korhonen P.K., Edoardo P., Giuseppe L.R., Gasser R.B.;
RT "Evolution of Trichinella species and genotypes.";
RL Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=a 1,2-diacyl-sn-glycero-3-phosphocholine + H2O = a 1-acyl-sn-
CC glycero-3-phosphocholine + a fatty acid + H(+); Xref=Rhea:RHEA:15801,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:28868,
CC ChEBI:CHEBI:57643, ChEBI:CHEBI:58168; EC=3.1.1.4;
CC Evidence={ECO:0000256|ARBA:ARBA00023422};
CC PhysiologicalDirection=left-to-right; Xref=Rhea:RHEA:15802;
CC Evidence={ECO:0000256|ARBA:ARBA00023422};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KRZ10158.1}.
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DR EMBL; JYDP01000063; KRZ10158.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0V1HH53; -.
DR Proteomes; UP000055024; Unassembled WGS sequence.
DR GO; GO:0047499; F:calcium-independent phospholipase A2 activity; IEA:InterPro.
DR GO; GO:0016042; P:lipid catabolic process; IEA:UniProtKB-UniRule.
DR Gene3D; 1.25.40.20; Ankyrin repeat-containing domain; 2.
DR Gene3D; 3.40.1090.10; Cytosolic phospholipase A2 catalytic domain; 1.
DR InterPro; IPR016035; Acyl_Trfase/lysoPLipase.
DR InterPro; IPR002110; Ankyrin_rpt.
DR InterPro; IPR036770; Ankyrin_rpt-contain_sf.
DR InterPro; IPR047148; PLPL9.
DR InterPro; IPR002641; PNPLA_dom.
DR PANTHER; PTHR24139:SF34; 85_88 KDA CALCIUM-INDEPENDENT PHOSPHOLIPASE A2; 1.
DR PANTHER; PTHR24139; CALCIUM-INDEPENDENT PHOSPHOLIPASE A2; 1.
DR Pfam; PF12796; Ank_2; 2.
DR Pfam; PF01734; Patatin; 1.
DR SMART; SM00248; ANK; 8.
DR SUPFAM; SSF48403; Ankyrin repeat; 1.
DR SUPFAM; SSF52151; FabD/lysophospholipase-like; 1.
DR PROSITE; PS50297; ANK_REP_REGION; 3.
DR PROSITE; PS50088; ANK_REPEAT; 3.
DR PROSITE; PS51635; PNPLA; 1.
PE 4: Predicted;
KW ANK repeat {ECO:0000256|ARBA:ARBA00023043, ECO:0000256|PROSITE-
KW ProRule:PRU00023}; Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Lipid metabolism {ECO:0000256|ARBA:ARBA00023098};
KW Reference proteome {ECO:0000313|Proteomes:UP000055024};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT REPEAT 185..207
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 356..388
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 389..421
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT DOMAIN 512..689
FT /note="PNPLA"
FT /evidence="ECO:0000259|PROSITE:PS51635"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:KRZ10158.1"
SQ SEQUENCE 834 AA; 92715 MW; 984219EA953F1862 CRC64;
LKRKRELMAN QPVHIYQDSK KINQVSKFVG NMVSAMREKV MGESWWLPSS CKTVVEIPTR
SIRLLVEQER HEQFAIFRAN ENATGANQLY HVVLYWLDNK MLSLRRFSDS NEASNYYNML
VHHSCLFQLI DNRKALDTLL DCIQAHSLWL PVHVAAKLGM KNYFEVIKSS ELSCKQQLSH
VCQPEGCYPL HIAVESGNVD LVVYMIDCLQ ASLTVTDIRG QTPFHYAART SPTMIAALAC
YDNEKSQINA LSKDGYTPLF LSISSCKPTC TAALLKQGAV LNIMCNGRSP IHMAMLQSGN
KLNEMIKTLV EASPDCIYQA DKQTGNSALH VAGNKQALNA LLSVCPDINL NCRNNAGQTA
LHLHTYLNNL SCVVALYYHG ADLNAKDTNG NTSLHIAVSA ENESMTKALL VLGADPNIVN
DNGHSPRHTA ARLNVRGREL MRCLIIGGAI RCPVESSGCA ATCSYRNADE SDLSVQYTAL
NYLETISVRK QEECIKKVVE MAATGKKFDV LLSLDGGGIR GVILILLYIE AALKKPLISY
VTWLAGTSTG GFLAAGLAKG KSLRDCQKIY LRMKDCLFEG RIRPYQSDAF EQLIKANIGE
TSKITDIVSP KLIITTVLAE KHPVQLHMFR NYTLPGDDNQ CCTQCSYIPD IPLWKVLRCS
SAAPTYFDSV DNKFVDGGLI ANNPALDLLS EFERYKSCQE FSECNEEASV GCLLSIGTGR
IPDMPIESLN LGFINVIDMV SAFKNLGYMI MDQVTAAEGR PVDRARSWCH CMGVPFFRFS
TPMSKDFALD TKSDQDLIQM MWETLEYVVN QRNEIAMLVE LLNTLHSNSR FTEA
//
