ID A0A0V1HHF3_9BILA Unreviewed; 1815 AA.
AC A0A0V1HHF3;
DT 16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT 16-MAR-2016, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE SubName: Full=Iron-sulfur cluster assembly enzyme ISCU, mitochondrial {ECO:0000313|EMBL:KRZ09913.1};
DE Flags: Fragment;
GN Name=Iscu {ECO:0000313|EMBL:KRZ09913.1};
GN ORFNames=T11_17190 {ECO:0000313|EMBL:KRZ09913.1};
OS Trichinella zimbabwensis.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Enoplea; Dorylaimia;
OC Trichinellida; Trichinellidae; Trichinella.
OX NCBI_TaxID=268475 {ECO:0000313|EMBL:KRZ09913.1, ECO:0000313|Proteomes:UP000055024};
RN [1] {ECO:0000313|EMBL:KRZ09913.1, ECO:0000313|Proteomes:UP000055024}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ISS1029 {ECO:0000313|EMBL:KRZ09913.1};
RA Korhonen P.K., Edoardo P., Giuseppe L.R., Gasser R.B.;
RT "Evolution of Trichinella species and genotypes.";
RL Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the NifU family.
CC {ECO:0000256|ARBA:ARBA00006420}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KRZ09913.1}.
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DR EMBL; JYDP01000066; KRZ09913.1; -; Genomic_DNA.
DR Proteomes; UP000055024; Unassembled WGS sequence.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0005506; F:iron ion binding; IEA:InterPro.
DR GO; GO:0051536; F:iron-sulfur cluster binding; IEA:InterPro.
DR GO; GO:0016226; P:iron-sulfur cluster assembly; IEA:InterPro.
DR CDD; cd16100; ARID; 1.
DR CDD; cd06664; IscU_like; 1.
DR CDD; cd20389; Tudor_ARID4_rpt1; 1.
DR Gene3D; 2.30.30.140; -; 1.
DR Gene3D; 3.90.1010.10; -; 1.
DR Gene3D; 1.10.150.60; ARID DNA-binding domain; 1.
DR Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 1.
DR InterPro; IPR001606; ARID_dom.
DR InterPro; IPR036431; ARID_dom_sf.
DR InterPro; IPR011339; ISCU.
DR InterPro; IPR001611; Leu-rich_rpt.
DR InterPro; IPR032675; LRR_dom_sf.
DR InterPro; IPR002871; NIF_FeS_clus_asmbl_NifU_N.
DR NCBIfam; TIGR01999; iscU; 1.
DR PANTHER; PTHR13964:SF27; HAT-TRICK, ISOFORM D; 1.
DR PANTHER; PTHR13964; RBP-RELATED; 1.
DR Pfam; PF01388; ARID; 1.
DR Pfam; PF14580; LRR_9; 1.
DR Pfam; PF01592; NifU_N; 1.
DR SMART; SM01014; ARID; 1.
DR SMART; SM00501; BRIGHT; 1.
DR SUPFAM; SSF46774; ARID-like; 1.
DR SUPFAM; SSF52058; L domain-like; 1.
DR SUPFAM; SSF82649; SufE/NifU; 1.
DR PROSITE; PS51011; ARID; 1.
DR PROSITE; PS51450; LRR; 2.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000055024};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 705..797
FT /note="ARID"
FT /evidence="ECO:0000259|PROSITE:PS51011"
FT REGION 171..288
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 679..706
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 807..890
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 913..1120
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1172..1710
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 171..252
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 253..278
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 837..860
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 866..884
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 937..951
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 984..1011
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1095..1109
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1191..1222
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1239..1263
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1264..1284
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1285..1309
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1322..1351
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1448..1481
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1498..1577
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1613..1644
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1645..1659
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1661..1681
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1687..1707
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:KRZ09913.1"
SQ SEQUENCE 1815 AA; 197183 MW; DC0C273EB0EFE0D9 CRC64;
LVDFAISVAD LFEMDKAKTS QALQIAMKGR EPEEMVALCL DNCRNPDIEQ LSERFVNLEE
LSLVNVGLQS LKKFPKLESL KKIDLSDNFI ANGLENLLNC PNLKHIQLNG NKINDFEQLE
CLKELKNLTH LDLFNCGVTD EEGYRQRIFA MIPQLKYVDG VDANDEYEDS DAEYDIEDEE
EEEVDEEQDD EERGSDDEED EDEEEEEAEV EESDGEEVEN EDEGEPESEE EDEEDMNNDG
IDEEDEEDEE EVVPEVRGKK RKHEDDDVLD HYENPRNVGS LDKSDPNVGT GVVGAPACGD
VMKLQIKVDE NGRITDAKFK TFGCCSAIAS SSLATEWIKG KSVEEALQVT NNEIAAELCL
PPVKLHCSML AEEAISAALN DYKSKQKKEC FAALNNDSVC RGVRDSIIRH LLEYNMLDPL
FFPIGSEVSA RFKGSFCQAI VKAVVPHLNC KILSNGTYFE VELNNIIGDV KVGNYVWFRN
PYNGSYNRGV IKVVKDKSDY TVDFDDGDEQ TLRRHQLCLR ASISPAPMES QVRGDAGSSG
ARVLQFAGSN VGGGDSGSSS ASLVPAPVNT NLVVGAVIIV QRNLPDMEQL IGESVDVTNQ
CFPALVVNSS AAPHLHCQSV VTANEVRNID DWQAREVENF VLRRGLENAR AYLEQGKLPC
GWDKDILLAA GTSAVRDVSG ELSASEETSK TAESSDVDSE DDTDDEDRDH FVACLYKFMD
ERNTPINKCP MLAGKDLDLY HFYRKVMRAG GYTRVTNKNL WKIITDKMSH SMGVNLTVKS
VRGAYESFLL SFENFTRKLG FPFKQYTPVT PRSATSRNEK EWMRSKALAE KIPAGDSANA
SRKRKKYTES VSDEARKEGG QKTASGGIVA EQQQQQQQQP EAVPVESETD LDEAKKLRLV
LAGEEQKTLP VVKALEPNGN DVSDKAVAAA PGSDDDGLSS KVKKKLKRAG GGNDGGNDGG
VGCVKKKLKP TGKTGKEKDV TKSETVVGTT AAGAASKSSS SSSTSSIDSS AGAGGKGKEA
AVSGKRKLAV GKSSRGRNVV AAKSTSVVGD GVGRASSKRK ASRSVSEDGS SLGVGDGEPR
KRCLVTVGAS GMRAASDDPS NNVQKRKQAT AEVSLKEEKP ELSASAAGKV FVAGDLTSVS
TTMVKLHGEK GTVESVQLDQ WKLVADNEQL FTASEISTDD AYDSEAEETA ESDSEKLGTE
NGAELVDEKN MVEMKKELTE ESVEVMQPVV AVQGDVVVEE ERGGQEEQQA VADEIEEPQK
KKKKKSEGKK KKKSKKKKKS KDKKEKGKKQ DNNDDDDDSK KDGSSKVVAN KKNKKKTHKV
AKKETAKEGK KGKDKLKKSG DKPAESKNKK KKKEGSGKKV AKKDAKEETA AAGTSGQGGG
EVKKPKRKVA KKKDANKPDT TTPGAAAAAK KKKKKTPKND DGEAAHAQTE GDVQGNNDGN
DNANKPKKTK KKVVKVVKNK KKDEKSVAKK KVGKKVKKTP TTAGTKKGAK KSTTSKLNEK
DNNAAVASTA TGKAAASSTS AAPSATSNTS SNGGGSNTTS NNNNSGKTNK NTSSTNTTST
GSGTGKSATS ASDAKGTDGA TGKTAANGAS LDVVVGNNKS LKNGNDKNKK DVNKKKKTTK
EKKKGKKGKK GKKDPGKRNT KLKRVVHFKT SELSQKSLKK NTKKGGGKSK NKSKGKKKPN
VPKKPQPSSQ PVKGQRKTSN NVVVPPQKKE KNNPFKILQK FIPDELKIEF PSKYSDMNFK
DVSLNMLEKE VDIVAVAPEF DPNKVFDFEQ TKMDIVESEH VTWLEGQMQL FKAKFRDINT
KIKQVERLRR RALAI
//
