ID A0A0V1HX85_9BILA Unreviewed; 1982 AA.
AC A0A0V1HX85;
DT 16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT 16-MAR-2016, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE SubName: Full=Notchless-like protein 1 {ECO:0000313|EMBL:KRZ15355.1};
GN Name=NLE1 {ECO:0000313|EMBL:KRZ15355.1};
GN ORFNames=T11_16581 {ECO:0000313|EMBL:KRZ15355.1};
OS Trichinella zimbabwensis.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Enoplea; Dorylaimia;
OC Trichinellida; Trichinellidae; Trichinella.
OX NCBI_TaxID=268475 {ECO:0000313|EMBL:KRZ15355.1, ECO:0000313|Proteomes:UP000055024};
RN [1] {ECO:0000313|EMBL:KRZ15355.1, ECO:0000313|Proteomes:UP000055024}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ISS1029 {ECO:0000313|EMBL:KRZ15355.1};
RA Korhonen P.K., Edoardo P., Giuseppe L.R., Gasser R.B.;
RT "Evolution of Trichinella species and genotypes.";
RL Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KRZ15355.1}.
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DR EMBL; JYDP01000018; KRZ15355.1; -; Genomic_DNA.
DR Proteomes; UP000055024; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-KW.
DR GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:UniProtKB-KW.
DR CDD; cd00200; WD40; 1.
DR Gene3D; 2.20.110.10; Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain; 1.
DR Gene3D; 2.130.10.30; Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II; 2.
DR Gene3D; 1.20.1050.80; VPS9 domain; 1.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 1.
DR InterPro; IPR020472; G-protein_beta_WD-40_rep.
DR InterPro; IPR003409; MORN.
DR InterPro; IPR012972; NLE.
DR InterPro; IPR009091; RCC1/BLIP-II.
DR InterPro; IPR000408; Reg_chr_condens.
DR InterPro; IPR003123; VPS9.
DR InterPro; IPR037191; VPS9_dom_sf.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR019775; WD40_repeat_CS.
DR InterPro; IPR036322; WD40_repeat_dom_sf.
DR InterPro; IPR001680; WD40_rpt.
DR PANTHER; PTHR46089; ALSIN HOMOLOG; 1.
DR PANTHER; PTHR46089:SF2; ALSIN HOMOLOG; 1.
DR Pfam; PF02493; MORN; 5.
DR Pfam; PF08154; NLE; 1.
DR Pfam; PF00415; RCC1; 2.
DR Pfam; PF02204; VPS9; 1.
DR Pfam; PF00400; WD40; 6.
DR PRINTS; PR00320; GPROTEINBRPT.
DR SMART; SM00698; MORN; 5.
DR SMART; SM00320; WD40; 7.
DR SUPFAM; SSF82185; Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain; 2.
DR SUPFAM; SSF50985; RCC1/BLIP-II; 2.
DR SUPFAM; SSF109993; VPS9 domain; 1.
DR SUPFAM; SSF50978; WD40 repeat-like; 1.
DR PROSITE; PS00626; RCC1_2; 1.
DR PROSITE; PS50012; RCC1_3; 4.
DR PROSITE; PS51205; VPS9; 1.
DR PROSITE; PS00678; WD_REPEATS_1; 2.
DR PROSITE; PS50082; WD_REPEATS_2; 6.
DR PROSITE; PS50294; WD_REPEATS_REGION; 5.
PE 4: Predicted;
KW Guanine-nucleotide releasing factor {ECO:0000256|ARBA:ARBA00022658};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000055024};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW WD repeat {ECO:0000256|ARBA:ARBA00022574, ECO:0000256|PROSITE-
KW ProRule:PRU00221}.
FT REPEAT 146..210
FT /note="RCC1"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00235"
FT REPEAT 211..261
FT /note="RCC1"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00235"
FT REPEAT 446..497
FT /note="RCC1"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00235"
FT REPEAT 498..549
FT /note="RCC1"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00235"
FT DOMAIN 1375..1526
FT /note="VPS9"
FT /evidence="ECO:0000259|PROSITE:PS51205"
FT REPEAT 1628..1669
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 1671..1717
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 1718..1758
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 1845..1886
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 1887..1928
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 1929..1954
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
SQ SEQUENCE 1982 AA; 224203 MW; 5854B3A4B741368C CRC64;
MKLQDTIITI FSHCSITLID ICRALLIKLN VNITIYCVAY LEYHFFMKTC LWTRGRGHSL
TCVNIDIPYQ PDQITVYCRD YCAEEANVIF VKDGIISEAT LNVLADEEES VFEKRREPLQ
SVILSGLRVQ SITFAYETFG AITSVGNIYM WGRSNYGQCG IIAENLAKPE RVEIRAADDY
CMHGERREPY DIQIVQLSIG GSEVLAVDRN GALWAWGAAF QNGGSTAWQP ICLPYRVPGL
LGRRVLSVAS GRTHHVALVE YIAGVDELHG FDEYAFLGNS SKCFQSNLPF VESCEHCQRG
RRSILTDWES TKSSSTDEPS SSPVGRCPLG VKLPFADDAE CFLEPRPECK SRSKPQVRQR
KLYSDAHCRG DEVELYELPR SKQQQASSSR LSFISFDLII PSSSSSSSLS EQTVSLDDSN
TLAGCVSGQS NLPGSSNLTE NTICLAELWT WGGNEFGQLG LNDFEPRCEP TRINGSSAFG
IVKIAAGAEH SIAMSSSGEV FVWGSNENRQ IKVADQWRVA VPMLFKAGSC AKVIDIAAGE
KFSAFLINGI DCRPECYICG YDRSDKVGTP VLRLYFPETS WPASLMCSDD YIICGCLEDT
DATLCNVFYQ IQFTLIRHVQ ILKQLVDLIN EIREESTFAD RFDESLFRRF AAGLRRYYLT
LANKSQSIKQ YLFMLDVKAT IEKSLEILLD SRFQNFLKQL NADYLILLSG DAFSLLKLNE
TVGKKLRYMC ELNSVEHHKQ SRLLQDVFFL PFTVFNDLHL IIAQFNGDDK FTKNTLKMLK
SVDRAAMNEK AQFLVKEFQR GQEPNEFVDV TENGRSVHCY LLAILSGSFF VVTKSSFRNY
KFPLVWTQNV QDDANLLVKV IVPEGELMIK FRDPSGTKEF VIAFNNALLL FLSKPCSEAP
LLCRPPLIRS GTHHFSAQNK TFLGAVYSGS WLLGKPHGNG HLTTKNNCVY RGHFRDGLMD
GYGEYKIVGE NGRWQFNKGQ WRAGILSGLV FIEYSDGSSY EGYFENNVRH GHGVHRQGSV
LYVGAWQNDK RQGYGVSDEC RSKYLGMWEN DLKHGLGTLV TLDGICYKGV FEKGAFKNGM
MLLTDGTMAK GEFNDVECLN GKASIYFPNG DYLEGFLSGR LQEQLKISNG NFYKNGCYSS
DGIKSEKDKQ NNNVHDFENS GFPPAEQKWN DIFAHVYHQL NCAENTSVVA STDKCWQSLV
VVCERFRKYF PTKKLQSSST NTADFIEKIP NYSMPCGEQY YYMVKNYCLQ AFQLQYHPLG
RLINGLSDIF NVSYSGVSVH SSLLVEAIEE IHSLLKRLYF VIKVLFPHLP GEQDMEGFVS
EFNFDLPLSS CLTTYNTFLY DSYLELVYPN IFTLFVIKNE ELDRVYWMNI RYVNSKSDVM
LLDHLGVEKQ FWPVIFTDTS DLDKPLACAT ARKKYYADAI DCFQRLSSEF FPSAKLKIIV
ETFEHINKCV SQGACEQELT AWTADSLVPV TTYVVVRAQI QRLGAEINFV QDFCPQLCNV
GEMQYMFATL QACYHYLKDV RRLAIRFQDE SGNPVGTVYD MPFNITAEQL ETVCNMEFRK
NEEPLKYSFF VNDLEIQNSL EETIDMNKIN MEQVLLIRYH AHAIYKVQTV TRCTSSLPGH
AETVISALFS HTDWVLCLSW SPDGQRLASG CKEGKICIWD PETGKQIGKT LVGHKLWITC
LCWEPLHQQG MARLLASSSK DHDIRIWDVV LNQTLRVLSG HSASVSCIRW GGEGLIYSAS
QDRTLKMWRV DKGILCRTFE GHGHWVNTIA LNTDYVLRTG AFDPKNSRID GTALPVTDPQ
QLKNLALDRY KKFTRNEPEM LVSGSDDFTL FLWSPSTNKK PLARMTGHQQ LINQVLFSPD
GRIIASASFD HSIKIWCGKT GKFLHTLRGH VQSVFQISWS SDSRLLVSGS ADSTLKLWDI
NARKLIVDLP GHADAVYAVD WSPRGDRVVS GGKDKLEKLR KVQQHFIHTD YYGCSKTVIE
FL
//
