ID A0A0V1HXM5_9BILA Unreviewed; 2015 AA.
AC A0A0V1HXM5;
DT 16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT 16-MAR-2016, sequence version 1.
DT 27-MAR-2024, entry version 30.
DE SubName: Full=Notchless-like protein 1 {ECO:0000313|EMBL:KRZ15354.1};
GN Name=NLE1 {ECO:0000313|EMBL:KRZ15354.1};
GN ORFNames=T11_16581 {ECO:0000313|EMBL:KRZ15354.1};
OS Trichinella zimbabwensis.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Enoplea; Dorylaimia;
OC Trichinellida; Trichinellidae; Trichinella.
OX NCBI_TaxID=268475 {ECO:0000313|EMBL:KRZ15354.1, ECO:0000313|Proteomes:UP000055024};
RN [1] {ECO:0000313|EMBL:KRZ15354.1, ECO:0000313|Proteomes:UP000055024}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ISS1029 {ECO:0000313|EMBL:KRZ15354.1};
RA Korhonen P.K., Edoardo P., Giuseppe L.R., Gasser R.B.;
RT "Evolution of Trichinella species and genotypes.";
RL Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KRZ15354.1}.
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DR EMBL; JYDP01000018; KRZ15354.1; -; Genomic_DNA.
DR STRING; 268475.A0A0V1HXM5; -.
DR Proteomes; UP000055024; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-KW.
DR GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:UniProtKB-KW.
DR CDD; cd00200; WD40; 1.
DR Gene3D; 2.20.110.10; Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain; 2.
DR Gene3D; 2.130.10.30; Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II; 2.
DR Gene3D; 1.20.1050.80; VPS9 domain; 1.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 1.
DR InterPro; IPR020472; G-protein_beta_WD-40_rep.
DR InterPro; IPR003409; MORN.
DR InterPro; IPR012972; NLE.
DR InterPro; IPR009091; RCC1/BLIP-II.
DR InterPro; IPR000408; Reg_chr_condens.
DR InterPro; IPR003123; VPS9.
DR InterPro; IPR037191; VPS9_dom_sf.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR019775; WD40_repeat_CS.
DR InterPro; IPR036322; WD40_repeat_dom_sf.
DR InterPro; IPR001680; WD40_rpt.
DR PANTHER; PTHR46089; ALSIN HOMOLOG; 1.
DR PANTHER; PTHR46089:SF2; ALSIN HOMOLOG; 1.
DR Pfam; PF02493; MORN; 5.
DR Pfam; PF08154; NLE; 1.
DR Pfam; PF00415; RCC1; 2.
DR Pfam; PF02204; VPS9; 1.
DR Pfam; PF00400; WD40; 6.
DR PRINTS; PR00320; GPROTEINBRPT.
DR SMART; SM00698; MORN; 5.
DR SMART; SM00320; WD40; 7.
DR SUPFAM; SSF82185; Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain; 2.
DR SUPFAM; SSF50985; RCC1/BLIP-II; 2.
DR SUPFAM; SSF109993; VPS9 domain; 1.
DR SUPFAM; SSF50978; WD40 repeat-like; 1.
DR PROSITE; PS00626; RCC1_2; 1.
DR PROSITE; PS50012; RCC1_3; 4.
DR PROSITE; PS51205; VPS9; 1.
DR PROSITE; PS00678; WD_REPEATS_1; 2.
DR PROSITE; PS50082; WD_REPEATS_2; 6.
DR PROSITE; PS50294; WD_REPEATS_REGION; 5.
PE 4: Predicted;
KW Guanine-nucleotide releasing factor {ECO:0000256|ARBA:ARBA00022658};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000055024};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW WD repeat {ECO:0000256|ARBA:ARBA00022574, ECO:0000256|PROSITE-
KW ProRule:PRU00221}.
FT REPEAT 146..218
FT /note="RCC1"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00235"
FT REPEAT 219..269
FT /note="RCC1"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00235"
FT REPEAT 454..505
FT /note="RCC1"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00235"
FT REPEAT 506..557
FT /note="RCC1"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00235"
FT DOMAIN 1408..1559
FT /note="VPS9"
FT /evidence="ECO:0000259|PROSITE:PS51205"
FT REPEAT 1661..1702
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 1704..1750
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 1751..1791
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 1878..1919
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 1920..1961
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 1962..1987
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
SQ SEQUENCE 2015 AA; 228110 MW; DB6E5D84B98FB2B5 CRC64;
MKLQDTIITI FSHCSITLID ICRALLIKLN VNITIYCVAY LEYHFFMKTC LWTRGRGHSL
TCVNIDIPYQ PDQITVYCRD YCAEEANVIF VKDGIISEAT LNVLADEEES VFEKRREPLQ
SVILSGLRVQ SITFAYETFG AITSVGNIYM WGRSNYGQCG IIAENLAKPE RSVNHVIVEV
EIRAADDYCM HGERREPYDI QIVQLSIGGS EVLAVDRNGA LWAWGAAFQN GGSTAWQPIC
LPYRVPGLLG RRVLSVASGR THHVALVEYI AGVDELHGFD EYAFLGNSSK CFQSNLPFVE
SCEHCQRGRR SILTDWESTK SSSTDEPSSS PVGRCPLGVK LPFADDAECF LEPRPECKSR
SKPQVRQRKL YSDAHCRGDE VELYELPRSK QQQASSSRLS FISFDLIIPS SSSSSSLSEQ
TVSLDDSNTL AGCVSGQSNL PGSSNLTENT ICLAELWTWG GNEFGQLGLN DFEPRCEPTR
INGSSAFGIV KIAAGAEHSI AMSSSGEVFV WGSNENRQIK VADQWRVAVP MLFKAGSCAK
VIDIAAGEKF SAFLINGIDC RPECYICGYD RSDKVGTPVL RLYFPETSWP ASLMCSDDYI
ICGCLEDTDA TLCNVFYQIQ FTLIRHVQIL KQLVDLINEI REESTFADRF DESLFRRFAA
GLRRYYLTLA NKSQSIKQYL FMLDVKATIE KSLEILLDSR FQNFLKQLNA DYLILLSGDA
FSLLKLNETV GKKLRYMCEL NSVEHHKQSR LLQDVFFLPF TVFNDLHLII AQFNGDDKFT
KNTLKMLKSV DRVFRFYKNI ASDTRKFRLK HANSSFLAAM NEKAQFLVKE FQRGQEPNEF
VDVTENGRSV HCYLLAILSG SFFVVTKSSF RNYKFPLVWT QNVQDDANLL VKVIVPEGEL
MIKFRDPSGT KEFVIAFNNA LLLFLSKPCS EAPLLCRPPL IRSGTHHFSA QNKTFLGAVY
SGSWLLGKPH GNGHLTTKNN CVYRGHFRDG LMDGYGEYKI VGENGRWQFN KGQWRAGILS
GLVFIEYSDG SSYEGYFENN VRHGHGVHRQ GSVLYVGAWQ NDKRQGYGVS DECRSKYLGM
WENDLKHGLG TLVTLDGICY KGVFEKGAFK NGMMLLTDGT MAKGEFNDVE CLNGKASIYF
PNGDYLEGFL SGRLQEQLKI SNGNFYKNGC YSSDGIKSEK DKQNNNVHDF ENSGFPPAEQ
KWNDIFAHVY HQLNCAENTS VVASTDKCWQ SLVVVCERFR KYFPTKKLQS SSTNTADFIE
KIPNYSMPCG EQYYYMVKNY CLQAFQLQYH PLGRLINGLS DIFNVSYSGV SVHSSLLVEA
IEEIHSLLKR LYFVIKVLFP HLPGEQDMEG FVSEFNFDLP LSSCLTTYNT FLYDSYLELV
YPNIFTLFVI KNEELDRVYW MNIRYVNSKS DVMLLDHLGV EKQFWPVIFT DTSDLDKPLA
CATARKKYYA DAIDCFQRLS SEFFPSAKLK IIVETFEHIN KCVSQGACEQ ELTAWTADSL
VPVTTYVVVR AQIQRLGAEI NFVQDFCPQL CNVGEMQYMF ATLQACYHYL KDVRRLAIRF
QDESGNPVGT VYDMPFNITA EQLETVCNME FRKNEEPLKY SFFVNDLEIQ NSLEETIDMN
KINMEQVLLI RYHAHAIYKV QTVTRCTSSL PGHAETVISA LFSHTDWVLC LSWSPDGQRL
ASGCKEGKIC IWDPETGKQI GKTLVGHKLW ITCLCWEPLH QQGMARLLAS SSKDHDIRIW
DVVLNQTLRV LSGHSASVSC IRWGGEGLIY SASQDRTLKM WRVDKGILCR TFEGHGHWVN
TIALNTDYVL RTGAFDPKNS RIDGTALPVT DPQQLKNLAL DRYKKFTRNE PEMLVSGSDD
FTLFLWSPST NKKPLARMTG HQQLINQVLF SPDGRIIASA SFDHSIKIWC GKTGKFLHTL
RGHVQSVFQI SWSSDSRLLV SGSADSTLKL WDINARKLIV DLPGHADAVY AVDWSPRGDR
VVSGGKDKLE KLRKVQQHFI HTDYYGCSKT VIEFL
//
