ID A0A0V1I6F8_9BILA Unreviewed; 2933 AA.
AC A0A0V1I6F8;
DT 16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT 16-MAR-2016, sequence version 1.
DT 27-MAR-2024, entry version 14.
DE SubName: Full=Metabotropic glutamate receptor 3 {ECO:0000313|EMBL:KRZ18451.1};
GN Name=GRM3 {ECO:0000313|EMBL:KRZ18451.1};
GN ORFNames=T11_14985 {ECO:0000313|EMBL:KRZ18451.1};
OS Trichinella zimbabwensis.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Enoplea; Dorylaimia;
OC Trichinellida; Trichinellidae; Trichinella.
OX NCBI_TaxID=268475 {ECO:0000313|EMBL:KRZ18451.1, ECO:0000313|Proteomes:UP000055024};
RN [1] {ECO:0000313|EMBL:KRZ18451.1, ECO:0000313|Proteomes:UP000055024}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ISS1029 {ECO:0000313|EMBL:KRZ18451.1};
RA Korhonen P.K., Edoardo P., Giuseppe L.R., Gasser R.B.;
RT "Evolution of Trichinella species and genotypes.";
RL Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KRZ18451.1}.
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DR EMBL; JYDP01000003; KRZ18451.1; -; Genomic_DNA.
DR STRING; 268475.A0A0V1I6F8; -.
DR Proteomes; UP000055024; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0004930; F:G protein-coupled receptor activity; IEA:InterPro.
DR Gene3D; 3.40.50.2300; -; 10.
DR InterPro; IPR001828; ANF_lig-bd_rcpt.
DR InterPro; IPR017978; GPCR_3_C.
DR InterPro; IPR028082; Peripla_BP_I.
DR PANTHER; PTHR24060:SF134; G_PROTEIN_RECEP_F3_4 DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR24060; METABOTROPIC GLUTAMATE RECEPTOR; 1.
DR Pfam; PF00003; 7tm_3; 1.
DR Pfam; PF01094; ANF_receptor; 3.
DR SUPFAM; SSF53822; Periplasmic binding protein-like I; 4.
DR PROSITE; PS50259; G_PROTEIN_RECEP_F3_4; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Receptor {ECO:0000313|EMBL:KRZ18451.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000055024};
KW Signal {ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..22
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 23..2933
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5006879716"
FT TRANSMEM 2614..2639
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 2651..2671
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 2677..2698
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 2719..2739
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 2772..2789
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 2801..2820
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 2832..2850
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 2643..2817
FT /note="G-protein coupled receptors family 3 profile"
FT /evidence="ECO:0000259|PROSITE:PS50259"
SQ SEQUENCE 2933 AA; 332661 MW; 9D426A6F7D64A2A8 CRC64;
MVNVNCCSLI ILFLTYGSTV FGGNIALEQC ASEQLQAEKN AAAIITLILD VRRTLHNHDG
PSCGTVSEEG LQIEEIAQWV IKILNQASGT VFGLPVADSF IPGIELGLQV LDTCGIASRA
IRLSAEAFSD LQSPKHKCTF NDTRISLGVI VKADDSTMHH LADFFHQYKK SVIGLGSRST
MLKQKQVFTV QPDIDAIVQT ILKTAETMEW KHLWLIYENT DYGNEGKTLL TKMSTQQQSI
CILGTEQFSH GTNSSENIKL ILEKILSKKE DSYLIILFMS RPVALQFLQT AFEEELMADS
RRMKWIMSDG FDGSFVDIFD LSKGVIAISD ENPYRIPEFL SHWTEADPKE HSKFWYKEFY
QHRHKCRLED DTNPAFYRFG VCKNKKSAIN HTDSELFLTP SAVHVVDAIF TYAIALKGAW
MAKCRGRPGL CPQLVQMDNQ DFIRFMKHVE FSYQKENRSP PSLISRQVSH RKPKSQVAVF
QVQSDEQANL LLKQIFRYDR FRNNRLLQLS APLFYDNFGK IDMEKKHSMT TNDKSHRCMT
FQKRKACHII PGDLYVIAII GIQEKGSYFD YCGQVNVEDS LADVVFFNHA LSSLNKKLLP
DLKIGSIVVD SCSNAIFAAQ QIGTCLTNME EIIFSETNND ASISKQPLFI GALIQADGLE
SAEISHLLSL TLPSLPIVMY GKNVVPGIAP NIINFGTNFQ NIADAVFNVI QQFPCHYKQF
IVARKYAPSV SVIESMAMNN LIGNFKTLLT NFGSNFDGIS AMNWIEKNAN WSVVVLFLEE
VQLLEFLKIA NQSATSSNHI YLIVLDHIWT FEKLRNFSHL ENNMIIFHTD NDVNYSLQDH
IINEAVDGIF NSKNIWIREY IENNLNCAKQ SEKNEHNAIV ASCKNETLLY LKKLALQHSI
KTNRLLASVD MLVATLHHVV KNNCFDGFTT GSKCSQFLES FLNLKENKML NYVTKHYEKI
SENDMFVLPK NIGIYFQSQL NNEKFQQIGT FSFNSKKFEI IDFSLFKNLS NQASSYCLNG
SSEKQYIEQS AVRKSEKLLT TLLPVTDMSN YLLQSENVKE MHISPENIVM HIPPLSKGES
VLIGVLLPLI GSANCEHLDY NKVKNEDAVY ALEALLWARK KIHILYNMDI QFIIFNTCSS
VSKTNILLNS FLINPQQFFG EKFGLNYTED LMVGFINGYS AGPASIASEI LSEASIVNAD
IRNNVQNRNS MTLHFSDNLT SYISAALQFL EQFQINFISI LYSNDEIAVT FTDKFRLKAN
NYNVCMAYIS QVDSTQSLNT LIDNLESVRN AGATVVLVVL EFQKLIAFER ALEKQSHGLT
FFIISLQNEI NAWNSNHFPV LLNSSILLKK QADLPKDFMN HLLQLRYDNN DGNYLWSDFV
KKKFNCTTEC NNRLPDVSDY AMLNADQVLS AVNALSALAV GVRKLGSTMC KNRTIVCKEL
KELPNFGSEL LHILQEEPFP AVDDISRKIR IDETRQVNEK LTISTTSILG SNETPLLQPI
AVYENEKLTL NRIGNEVKNQ SVFTSQCLDI HQCKQCWKSM DKLLNSYMRK FSPALEVHTE
SSDHVEEISS IPEEEAANVE KKTNKQIAES KSFVCIKSTS NIYLMAVIPI HNREQKRLAC
GAFSSNQYQR WKAIQWSLER LNYYLLAQTS INLGIIAIDS CSDQAHTIKQ LSYLINGDMQ
LNSCIQGNFS DQVIAAILVP YNQQDTSHEA TVDLLTNNGI LTFNWDSSFA YSANSMLFST
GLIEQSFVNG LVKFLAKTKW HYVAYIYSKN KNSMRRKHIF SNLANDNGIC SEYILYPSHN
KHSCGEMTEL FDQLKKIQVN GLRGVVLGLS MNKLRCFLDR MERLVASGQF SPNQFTFITA
LDANYKQAFF RYESVAAGFV VVHPTAVELD EFHQYWKALK HLNVSNDIWW KELLATDDWP
ERQDEKLLYL ANAAYSVGHA IYETKQQLCG SGMTASKKCN NLIMHHSFRK AFQKNVATSK
FVDESGQMFT FDKDGLATQR VSISLLVMDL DIVQWIEIGR IENDVFDTKQ RGNSPFQNYE
PMLYLQKLTS KCTNATLCPQ CSRCPSLVQL LTCPSVHCKN EFGKSTPPAQ LDVTTEKIHL
PASNLHYSES KLHWIVHSPN GIYAIALVPV HFPSEELFLC GPLDIFGGFR QASAFMHSME
KLNKQLPKQN QIGLIIIDTC NAKSDLAFSW IHQLSINNQS VQILAVLDAA YSNSNSNELA
ELMKNLQIPL LTIDPKLEMS KNEWNLHFKF DLNWYAEIAC SVVHRLKFIT PLVLFEQSNK
LHSSIMEKFI YCLESNNFNN VITKIPVNNY RELDAILNGL SNRPTAVFVL FMSSTFISAF
RRAIIQQPYN IGQTIVLGYG LERIFTTTSP IKQAEQHSDM ITWLSIELLI ENEADTSEFL
FSKQLNNYYP IPQYWFEEYW QQMFTCKLSN SEIVGNFHFY KNCTEKEQIN STALSKNLES
DISVWFLMNV VVDGYIKYVD NDCAQVSTAA QPIRLVNCLK NGNRSNLLKY LKSSNWNQIA
VGNEFNNHKT LENCKIVLKK IYMDKDQLHT ESVALWKQTF TLSINGKPTS SSSSSSSSSS
SKDILCKTSV EENCWKRFDF TVSNLEETNR MNEIWIVIAI SLAGLGMTVC IITSIVLIVT
DHASNDMFNH LTLFGLFNLY AVTLAFTWQL SDIVCTIRLY ATGFAWTLVF APLSVKVVQM
RLFPENGKKQ AYCWKKRNCI MVILAIVFVH AISVVQWMIV NKSTKIPVLF KHAKCAPVGN
LATFELSLTF SMAYPILIIL ATMITAMTTT TNTSKYNKSS CGIAVTCMLT IIIWLFWNIT
STMEIFQLSD PVIAMGILIN ASVLFVGLRL RDNKNTSTQS RRSYNVNMIR NEASLQPDLS
LVPYGVNFSK SKLGTFDSDQ SYSTYSTVPK TKRYFNVMAY DGSSEFSATT MVN
//
