ID   A0A0V1IAC7_9BILA        Unreviewed;       942 AA.
AC   A0A0V1IAC7;
DT   16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT   16-MAR-2016, sequence version 1.
DT   24-JAN-2024, entry version 12.
DE   SubName: Full=Patched domain-containing protein 3 {ECO:0000313|EMBL:KRZ19396.1};
GN   Name=Ptchd3 {ECO:0000313|EMBL:KRZ19396.1};
GN   ORFNames=T11_12294 {ECO:0000313|EMBL:KRZ19396.1};
OS   Trichinella zimbabwensis.
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Enoplea; Dorylaimia;
OC   Trichinellida; Trichinellidae; Trichinella.
OX   NCBI_TaxID=268475 {ECO:0000313|EMBL:KRZ19396.1, ECO:0000313|Proteomes:UP000055024};
RN   [1] {ECO:0000313|EMBL:KRZ19396.1, ECO:0000313|Proteomes:UP000055024}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ISS1029 {ECO:0000313|EMBL:KRZ19396.1};
RA   Korhonen P.K., Edoardo P., Giuseppe L.R., Gasser R.B.;
RT   "Evolution of Trichinella species and genotypes.";
RL   Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the patched family.
CC       {ECO:0000256|ARBA:ARBA00005585}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KRZ19396.1}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; JYDP01000001; KRZ19396.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A0V1IAC7; -.
DR   Proteomes; UP000055024; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   Gene3D; 1.20.1640.10; Multidrug efflux transporter AcrB transmembrane domain; 2.
DR   InterPro; IPR003392; Ptc/Disp.
DR   InterPro; IPR000731; SSD.
DR   PANTHER; PTHR10796; PATCHED-RELATED; 1.
DR   PANTHER; PTHR10796:SF92; PATCHED-RELATED, ISOFORM A; 1.
DR   Pfam; PF02460; Patched; 1.
DR   SUPFAM; SSF82866; Multidrug efflux transporter AcrB transmembrane domain; 2.
DR   PROSITE; PS50156; SSD; 1.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000055024};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        28..48
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        269..289
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        301..329
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        335..358
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        379..397
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        403..431
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        529..548
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        736..755
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        762..783
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        789..815
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        835..858
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        864..885
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          272..431
FT                   /note="SSD"
FT                   /evidence="ECO:0000259|PROSITE:PS50156"
SQ   SEQUENCE   942 AA;  106930 MW;  8C9A57C871881A36 CRC64;
     MPQKMEFFEA NLRRLSERYA RIVYRNPAWF VVVPVIVGIA LSTGLLFLNK YDNALYLYTP
     LNGLAKQEER IFESFWPTTE QDSFSPSKIF NGKGQCHLYV KSKNGSNLLT AKYLLAIEEL
     NRYVIEDIQI TDNGTAYAYN DICLQWKHSC YDNPLIEIFK QFYFKNVAHL NFSYPKVAIS
     DQVIYVASTL GGVTVSNSSG RIEHAEAWLL IYQLRVWDQL DEHRKFLWQN KFRDHILSYE
     SPLLELSLYH DEVLDQELNR NAKVLAPRIA PSFILLLIFS AVFTFHITIR NGRIHFHYAS
     LSPLVAIAGV FSAGLGVSTA IGLLSYIGIQ FSRVVVVMPF LVVAVRIDNT FLMISALASI
     DRKTKTEDRV AEAMSEASVS IFLTVATDAL SFAVGYITNF PAVQLFCLYT CTAILVTFVF
     QLTLLFALLV YEARRESKFS EDNLESKKSV ISFTASSIST FLKPILRPKQ TDNDQTLKST
     TKVNGIALPA SAVGNGRAVV KYNETQLFTT FFADYYAPFL MRPCVKTMVI VLFFAYITVS
     TYGCMYIREG LEPARLLPVG SYALKHYRNL EKYLWKYGMQ IAIVVANPGN LSDTANRERL
     IEVIHEFALS KHGIGEEGIS CWLLDFQKFL ELNIKVQIDE IPQSSFYDYV KLFLSMPGNG
     AYKEDLVWTV DEINSTFRIT AFRFMIGIKD FVDTIAQTET VVEFRNIASK YPEYNITSFN
     KMWHYVDQYL EIVPNIIQEC AYGIMCMVIL ALLLIPKAVC SLWVTFSIFS IDMGVIGFMT
     LWGLNMDTIS MITIIMSIGF SVDFSAHIAF SYSIYPHSDP VQRIRYSLGQ LGWPILQGAL
     STLLGVSLLA DLGSYMIISF FKTVFLVIIS GLLHALIFLP VFLTLTDQWH SLLCKPKSAS
     IARRNTRSLS TSRQNCRNST EAESRLTITI QNDPKHVRPE AC
//