ID A0A0V1L4V6_9BILA Unreviewed; 1217 AA.
AC A0A0V1L4V6;
DT 16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT 16-MAR-2016, sequence version 1.
DT 27-MAR-2024, entry version 33.
DE RecName: Full=BK channel {ECO:0000256|ARBA:ARBA00029579};
GN Name=slo-1 {ECO:0000313|EMBL:KRZ54373.1};
GN ORFNames=T02_43 {ECO:0000313|EMBL:KRZ54373.1};
OS Trichinella nativa.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Enoplea; Dorylaimia;
OC Trichinellida; Trichinellidae; Trichinella.
OX NCBI_TaxID=6335 {ECO:0000313|EMBL:KRZ54373.1, ECO:0000313|Proteomes:UP000054721};
RN [1] {ECO:0000313|EMBL:KRZ54373.1, ECO:0000313|Proteomes:UP000054721}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ISS10 {ECO:0000313|EMBL:KRZ54373.1};
RA Korhonen P.K., Edoardo P., Giuseppe L.R., Gasser R.B.;
RT "Evolution of Trichinella species and genotypes.";
RL Submitted (MAY-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KRZ54373.1}.
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DR EMBL; JYDW01000139; KRZ54373.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0V1L4V6; -.
DR Proteomes; UP000054721; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005216; F:monoatomic ion channel activity; IEA:InterPro.
DR GO; GO:0006813; P:potassium ion transport; IEA:InterPro.
DR Gene3D; 1.10.287.70; -; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 2.
DR InterPro; IPR005821; Ion_trans_dom.
DR InterPro; IPR003929; K_chnl_BK_asu.
DR InterPro; IPR047871; K_chnl_Slo-like.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR048735; Slowpoke-like_C.
DR PANTHER; PTHR10027; CALCIUM-ACTIVATED POTASSIUM CHANNEL ALPHA CHAIN; 1.
DR PANTHER; PTHR10027:SF33; CALCIUM-ACTIVATED POTASSIUM CHANNEL SUBUNIT ALPHA-1; 1.
DR Pfam; PF03493; BK_channel_a; 2.
DR Pfam; PF00520; Ion_trans; 1.
DR Pfam; PF21014; Slowpoke_C; 1.
DR PRINTS; PR01449; BKCHANNELA.
DR PRINTS; PR00169; KCHANNEL.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR SUPFAM; SSF81324; Voltage-gated potassium channels; 1.
PE 4: Predicted;
KW Calcium {ECO:0000256|ARBA:ARBA00022837};
KW Ion channel {ECO:0000256|ARBA:ARBA00023303, ECO:0000313|EMBL:KRZ54373.1};
KW Ion transport {ECO:0000256|ARBA:ARBA00023065};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Potassium {ECO:0000256|ARBA:ARBA00022958};
KW Potassium channel {ECO:0000256|ARBA:ARBA00022826};
KW Potassium transport {ECO:0000256|ARBA:ARBA00022538};
KW Reference proteome {ECO:0000313|Proteomes:UP000054721};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 42..66
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 158..178
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 199..217
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 223..246
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 282..303
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 319..337
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 349..366
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 159..375
FT /note="Ion transport"
FT /evidence="ECO:0000259|Pfam:PF00520"
FT DOMAIN 528..602
FT /note="Calcium-activated potassium channel BK alpha
FT subunit"
FT /evidence="ECO:0000259|Pfam:PF03493"
FT DOMAIN 604..650
FT /note="Calcium-activated potassium channel BK alpha
FT subunit"
FT /evidence="ECO:0000259|Pfam:PF03493"
FT DOMAIN 1085..1201
FT /note="Ca2+-activated K+ channel Slowpoke-like C-terminal"
FT /evidence="ECO:0000259|Pfam:PF21014"
SQ SEQUENCE 1217 AA; 138241 MW; 6E28901201B0863E CRC64;
MSEFHKGGGG GLGLYPLNCN QTPYRFETMT EEERRCLDER KYWCFLLSSI ITFCLSMLLV
VTYRILSHLF CSRPKDRDRF DDPNDTASVD DDKRTTDNKF FHDSCQSTAN VDEKLTLSVV
ASSQQQQSTT NESHVGWMTE AKDWAGELIS GQSTTGRILV VLVFVLSIAS LIIYFYDASN
PHFQVETCIP LSQSPSQQID LAFNIFFLIY FFIRFIAATD KVWFLLEVYS FVDYFTIPPS
FVAIYLERNW LGLRFLRALR LMTLPDILQY LNIMKTSNAI RLAQLVSIFV SVSLTAAGFI
HLLENSGDPF QNFENPQRIT YWECVYFLLV TMSTVGYGDI YCKTTLARLF MVFFILGGLA
MFASYVPEIA DLIGARQKYG GQYKGEHGKK HIVVCGFITF ESVSHFLQDF LHEDREDVDV
EVIFLHRVPP DLELEGLFKR HFTKVEFFQG TVMDSVDLTR VKIDEADACL VLANKYSPDP
DAEDAANIMR VISIKNYSAD IRVIVQLMQY HNKAYLLNIP SWDWRRGDDV ICLAELKLGF
IAQSCLAPGF STMMANLFAM RSFKTSPNMP GWLNEYLRGA GMEMYTENFS PSFYGMTFPD
AADPEWLRYY LCGASMEVYP EILSHSFVGM SYAEAAYILY TKLGLLLLAI EMRDEEKREC
NIAINPGSSV RIDPHTQGFF IAQSADEVKR AFFYCNLCHA DIQDVTLIKK CKCKNCAGTF
PKRDQADCND EYFDSEINCL GRKVSTAVVR DTDRRMSDTR SRHISDARAA INRKAYKLEL
AYNKYPDFDN HRSKDMRDMY NPKGFLLAYE LLSSSMPKIT RKKSFGGSIA PKIDPELLKD
FEQQAIKYDS TGMFHWCPGR PIEESILERN QAKMTVLHGH VVVCLFADKD SPLIGLRNFV
MPLRASNFHY HELKQVVIVG DVEYLRREWK TLYNLPKISI LNGSPLSRAD LRAVNINTCD
MCVILSARIP NPTEDPTLAD KEAILASLNI KAMQFEDSPL LYPLPEGISP LSTPVKMSKM
LVKFGTQVPM ITELVNDSNV QFLDQDDEDD PDTELYLTQP FACGTAFAIS VLDSLMSTTY
FNDSALTLIR TLVTGGATPE LELILAEGAG LRGGMSTPET LRNRDRCRVA QLSLADGCFQ
SYHIGATYGQ VLSQALKDYG MLCIGLYRLH DTSTDDLEKR YVITNPPPDL KLISTDKVYV
LQPYDHGLEY PAREMEE
//
