ID A0A0V1L6W0_9BILA Unreviewed; 895 AA.
AC A0A0V1L6W0;
DT 16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT 16-MAR-2016, sequence version 1.
DT 24-JAN-2024, entry version 18.
DE RecName: Full=DNA polymerase alpha subunit B {ECO:0000256|ARBA:ARBA00018596};
GN Name=POLA2 {ECO:0000313|EMBL:KRZ55283.1};
GN ORFNames=T02_575 {ECO:0000313|EMBL:KRZ55283.1};
OS Trichinella nativa.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Enoplea; Dorylaimia;
OC Trichinellida; Trichinellidae; Trichinella.
OX NCBI_TaxID=6335 {ECO:0000313|EMBL:KRZ55283.1, ECO:0000313|Proteomes:UP000054721};
RN [1] {ECO:0000313|EMBL:KRZ55283.1, ECO:0000313|Proteomes:UP000054721}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ISS10 {ECO:0000313|EMBL:KRZ55283.1};
RA Korhonen P.K., Edoardo P., Giuseppe L.R., Gasser R.B.;
RT "Evolution of Trichinella species and genotypes.";
RL Submitted (MAY-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the DNA polymerase alpha subunit B family.
CC {ECO:0000256|ARBA:ARBA00007299}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KRZ55283.1}.
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DR EMBL; JYDW01000118; KRZ55283.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0V1L6W0; -.
DR STRING; 6335.A0A0V1L6W0; -.
DR Proteomes; UP000054721; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
DR Gene3D; 3.60.21.60; -; 2.
DR Gene3D; 1.10.8.530; DNA polymerase alpha-primase, subunit B, N-terminal domain; 1.
DR InterPro; IPR007185; DNA_pol_a/d/e_bsu.
DR InterPro; IPR043034; DNA_pol_alpha_B_N_sf.
DR InterPro; IPR016722; DNA_pol_alpha_bsu.
DR InterPro; IPR031947; Headcase_mid.
DR PANTHER; PTHR23061; DNA POLYMERASE 2 ALPHA 70 KDA SUBUNIT; 1.
DR PANTHER; PTHR23061:SF12; DNA POLYMERASE ALPHA SUBUNIT B; 1.
DR Pfam; PF04042; DNA_pol_E_B; 1.
DR Pfam; PF16002; Headcase; 1.
PE 3: Inferred from homology;
KW DNA replication {ECO:0000256|ARBA:ARBA00022705};
KW Reference proteome {ECO:0000313|Proteomes:UP000054721}.
FT DOMAIN 180..306
FT /note="Headcase middle"
FT /evidence="ECO:0000259|Pfam:PF16002"
FT DOMAIN 635..845
FT /note="DNA polymerase alpha/delta/epsilon subunit B"
FT /evidence="ECO:0000259|Pfam:PF04042"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:KRZ55283.1"
SQ SEQUENCE 895 AA; 101176 MW; B18F13FADBA2F2A3 CRC64;
LYITSHEISF FIYCLEHFFV DQSRNMTDAI NDVVKVECNN LSCPSEKCVD RLCFETRQTS
LQSFDRLNVF AQNCTGVGSC SRGCLKCDTA QYTACEERFK HLPFRRENGN KVASLSKKSG
FGSGFFRARS RTSSFDSAVV AFDSEGSAMS KSKSNQFILE SCEHDTGILN NSSHCLDMQA
QSTGNIFRRR QNLESFRKAL PRSKINGINI KLEDDCPQGN DETRLFVLTN LGDHKRRTVT
CIICQSLLPV YDRYPLIDGT FFLSPINHEN SGVMVNYEGS SLYLLSLCMY CMESAPKLMC
ILCGSEGWFI ETVKIEDIAQ QFSYLGFMFN SADDVQVCNN ILRICSNLKW KAEEFVDQWI
SFSLSNSMTE MSVENLNIME RNFLRNRRQE HCGQLSPRKS FLNDSKISEI TNTSFEMSKE
LLSAYISDHQ DDSAIEDVME NSQQIELSSP CAAILKRSSS AKLIFSFQPN VTLEWIVPEM
GRNITVQPFN CKQFLYKSYR YMYEKLEDRM ETLGKMIDSI GGAVMRSVGE GKELLPVDSV
SDEMIYICGQ VYSFSGLLKS SKDVHLQGKS DHGFSEVTLD LSSVKQYAIF PGQIIVAKGF
GLHSHIFAAD EIYPGELAPI PVKTLDEVVQ CNLLFVIACG PFCYADDNNF IALQELVNYC
LQVKASSLIL IGPFFYNENI KPLSQDDVSY EELLCKMLFN ICETLSANFT NVIIVASPKD
TFSSQIYPCP PYRLKWRAFI GENGEQPDNL FFAPDPCLLN VGGVIVGITS TDILWHLKNE
ELVEGIQQGE RVNRMITHLL MQRSFYPLCP SGDATVEYSK LKLYGELSVR PDILILPSKF
HHFIKSIHKT VCVNPGNFVK AKSTGTFATM KIFINQLLQK TDDFENCVLG EILRL
//
