ID A0A0V1L7A0_9BILA Unreviewed; 447 AA.
AC A0A0V1L7A0;
DT 16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT 16-MAR-2016, sequence version 1.
DT 24-JAN-2024, entry version 26.
DE RecName: Full=Protein Wnt {ECO:0000256|RuleBase:RU003500};
GN Name=WNT2 {ECO:0000313|EMBL:KRZ55408.1};
GN ORFNames=T02_13598 {ECO:0000313|EMBL:KRZ55408.1};
OS Trichinella nativa.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Enoplea; Dorylaimia;
OC Trichinellida; Trichinellidae; Trichinella.
OX NCBI_TaxID=6335 {ECO:0000313|EMBL:KRZ55408.1, ECO:0000313|Proteomes:UP000054721};
RN [1] {ECO:0000313|EMBL:KRZ55408.1, ECO:0000313|Proteomes:UP000054721}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ISS10 {ECO:0000313|EMBL:KRZ55408.1};
RA Korhonen P.K., Edoardo P., Giuseppe L.R., Gasser R.B.;
RT "Evolution of Trichinella species and genotypes.";
RL Submitted (MAY-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Ligand for members of the frizzled family of seven
CC transmembrane receptors. {ECO:0000256|RuleBase:RU003500}.
CC -!- SUBCELLULAR LOCATION: Secreted, extracellular space, extracellular
CC matrix {ECO:0000256|ARBA:ARBA00004498, ECO:0000256|RuleBase:RU003500}.
CC -!- SIMILARITY: Belongs to the Wnt family. {ECO:0000256|ARBA:ARBA00005683,
CC ECO:0000256|RuleBase:RU003500}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KRZ55408.1}.
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DR EMBL; JYDW01000115; KRZ55408.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0V1L7A0; -.
DR STRING; 6335.A0A0V1L7A0; -.
DR Proteomes; UP000054721; Unassembled WGS sequence.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-KW.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0005102; F:signaling receptor binding; IEA:InterPro.
DR GO; GO:0048699; P:generation of neurons; IEA:UniProt.
DR GO; GO:0016055; P:Wnt signaling pathway; IEA:UniProtKB-KW.
DR InterPro; IPR005817; Wnt.
DR InterPro; IPR018161; Wnt_CS.
DR PANTHER; PTHR12027:SF37; PROTEIN WNT; 1.
DR PANTHER; PTHR12027; WNT RELATED; 1.
DR Pfam; PF00110; wnt; 1.
DR PRINTS; PR01349; WNTPROTEIN.
DR SMART; SM00097; WNT1; 1.
DR PROSITE; PS00246; WNT1; 1.
PE 3: Inferred from homology;
KW Developmental protein {ECO:0000256|ARBA:ARBA00022473,
KW ECO:0000256|RuleBase:RU003500};
KW Extracellular matrix {ECO:0000256|ARBA:ARBA00022530};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000054721};
KW Secreted {ECO:0000256|ARBA:ARBA00022525};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius};
KW Wnt signaling pathway {ECO:0000256|ARBA:ARBA00022687,
KW ECO:0000256|RuleBase:RU003500}.
FT TRANSMEM 149..172
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 447 AA; 49865 MW; 90ED1DB1625B0C54 CRC64;
MRARYYASMS ERSLSEKSVS SDLQFSGGLA EAAALFQLVR PGGHLRGLAK LTKTVVKEME
KKTQDTSHKW CPRPRHVIYV AHYDSMACFL KPNGQKQPPG RRLLRPISPD RRHRCLWPIS
TDGGCRSSSM WIRLMSDSSV LSSPAMVKWL RLLIISLLCT GCLAQASAWW LMSQMQMSAV
SGSSPALCDL IPGLGRRQRR LCQLHPDVMK AISDGIRRGV AECQTQFAGY RWNCTTVEGG
GFGRIILKLG SREAAFVYSI STASVVHSIA RSCSTSQISD CSCDRRRVGR GQDSQGEFSW
GGCSDNLPYA ISFARKFIDS KDRRSRDGRA LMNLHNNRAG RKAVKRNLKI QCKCHGVSGS
CATRTCWRAL PHLSIIGADL ADKYHEALQV TVNPNGEGLI PADHRRYDFL YGPKAALFQR
KRINRAELVY FEPSPDYCEA DIRTGKI
//
