ID A0A0V1L7I6_9BILA Unreviewed; 3261 AA.
AC A0A0V1L7I6;
DT 16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT 16-MAR-2016, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE SubName: Full=HHIP-like protein 1 {ECO:0000313|EMBL:KRZ55515.1};
GN Name=HHIPL1 {ECO:0000313|EMBL:KRZ55515.1};
GN ORFNames=T02_10531 {ECO:0000313|EMBL:KRZ55515.1};
OS Trichinella nativa.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Enoplea; Dorylaimia;
OC Trichinellida; Trichinellidae; Trichinella.
OX NCBI_TaxID=6335 {ECO:0000313|EMBL:KRZ55515.1, ECO:0000313|Proteomes:UP000054721};
RN [1] {ECO:0000313|EMBL:KRZ55515.1, ECO:0000313|Proteomes:UP000054721}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ISS10 {ECO:0000313|EMBL:KRZ55515.1};
RA Korhonen P.K., Edoardo P., Giuseppe L.R., Gasser R.B.;
RT "Evolution of Trichinella species and genotypes.";
RL Submitted (MAY-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00196}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KRZ55515.1}.
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DR EMBL; JYDW01000113; KRZ55515.1; -; Genomic_DNA.
DR STRING; 6335.A0A0V1L7I6; -.
DR Proteomes; UP000054721; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR CDD; cd00037; CLECT; 1.
DR Gene3D; 3.10.100.10; Mannose-Binding Protein A, subunit A; 1.
DR Gene3D; 2.160.20.10; Single-stranded right-handed beta-helix, Pectin lyase-like; 1.
DR Gene3D; 3.10.250.10; SRCR-like domain; 3.
DR InterPro; IPR039448; Beta_helix.
DR InterPro; IPR016186; C-type_lectin-like/link_sf.
DR InterPro; IPR016187; CTDL_fold.
DR InterPro; IPR006626; PbH1.
DR InterPro; IPR012334; Pectin_lyas_fold.
DR InterPro; IPR011050; Pectin_lyase_fold/virulence.
DR InterPro; IPR001190; SRCR.
DR InterPro; IPR017448; SRCR-like_dom.
DR InterPro; IPR036772; SRCR-like_dom_sf.
DR PANTHER; PTHR47653:SF1; DELETED IN MALIGNANT BRAIN TUMORS 1 PROTEIN; 1.
DR PANTHER; PTHR47653; PROTEIN BARK BEETLE; 1.
DR Pfam; PF13229; Beta_helix; 1.
DR Pfam; PF00530; SRCR; 3.
DR SMART; SM00710; PbH1; 16.
DR SMART; SM00202; SR; 3.
DR SUPFAM; SSF56436; C-type lectin-like; 1.
DR SUPFAM; SSF51126; Pectin lyase-like; 2.
DR SUPFAM; SSF56487; SRCR-like; 3.
DR PROSITE; PS50287; SRCR_2; 3.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157, ECO:0000256|PROSITE-
KW ProRule:PRU00196}; Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000054721};
KW Signal {ECO:0000256|SAM:SignalP}; Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..23
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 24..3261
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5006881605"
FT TRANSMEM 2814..2842
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 126..232
FT /note="SRCR"
FT /evidence="ECO:0000259|PROSITE:PS50287"
FT DOMAIN 1108..1219
FT /note="SRCR"
FT /evidence="ECO:0000259|PROSITE:PS50287"
FT DOMAIN 1973..2084
FT /note="SRCR"
FT /evidence="ECO:0000259|PROSITE:PS50287"
FT REGION 2987..3045
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 3100..3126
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 3211..3261
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2987..3003
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 3211..3252
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT DISULFID 196..206
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00196"
FT DISULFID 1185..1195
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00196"
FT DISULFID 2049..2059
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00196"
SQ SEQUENCE 3261 AA; 370176 MW; CFAE4367003FF0A9 CRC64;
MAKRTVLLVF LFVTLNRITF TTATFDDQQQ QQQLLVAHFQ EAGGTYTLNH TLYYQDGPYK
VTKPILIQAG AVLTIEQGVQ LYFASGVGVV VQGVLQAVGN KYLQIDFLPW RTPIQELEHE
SSFPNLRLVD GPSTRQGRLQ VLHNGRWRAV CTMMTNWTDV DYQTACRTMG FDSGGFWKWY
RRNNDTRPFV MPLPGCNATH ETIEHCTNWT SDRIQLSENL CQGEDDLGLV CWGPPSFHGW
HFHWKGIEFQ DAPWHYVPVD GIATKKESRS RLEYVNIWYA GYDKEVQNTT AAILARGMPP
FMNYVDIKYS ARDGIRVIAP DGPVEITNST IAHNRGHGVV VENTTDGRLF INETRIMFNY
GNGIYFRPKL GLSYRPVIDE PLGRESVVYY EPETPEMDIC RQHEFNSKRK WFPRIYAAHL
KNSTTLVSET NNWPCYVHIT VTVWENARVL VEGQSSDPQW TCAIAQTVSC RSFDRPVQLT
AIYLTPSVYS TVRKLIVTNI ITLTSGQFFS AEITGEPEMT MMKSSIASMD FGRRLPITYS
IQFLEMTGLS LLNNDAQLFL YVCDSTRGQD LCKFPRYKIP VLNGYMPPTV EAQNTGGSLW
IGLRSEGSNI TLNETVNVVM KIHASFGDQV FYGLNVSNCR ITDNFGTGVY VENMRDRTVI
NNVTILRNQH VAGLHVCEGV GDIWVNNSLI LDNWGDGINI TYTGGSTVIN GTQLSRNRMR
GFALHQSLRG KFLALKQEVV FKGRPATNTD YTPTKVEENW WGGILVGNFC TSDSNYWLGD
PKVIISYVEM VGNRYHPSFE YHSCQREKQP ITEVEISGSV CRLATGFCVR VQPAVNLRMD
INDNRFIRNE RAVLLIRNRD HPQLFHLPAR VSITRNQMKY NRGYFIVSVG LNDRSPVQNL
TFHMQNEIKE NEVINPFPLL NTRTLPHAAM IVSSSNVMLR RNCFHNPKAE FEIATDLDDH
SRVIDARENN WGHTQPASFM YKIFDQFKRY TLARFDINPY AAVCNSQNPK MTELMNFFRQ
FRTASHPYVI GGTIYENTDL AKGVYTVVDD LHISPGAVLT LQPGTVLQFA DGIGMLVQGE
LLRADYQGSS EPILFTLAKR DPISVSNIRL VQDDSERSTL APASGRLEVF VDGEWGTVCN
RSWTVELAAV ACNQLGMVLD PEFLENWVVY PSPGNLPIIF DNIRCEELEY DITKCRHDGR
NESVHLSCKP TDIVGLRCVE PKWAGVRYSL LANPAMVTGQ TTIRHLIIEK AGLLDFRQPT
FTAAFQIDWN YHLFEYLTVR DNFWTGVDIL YNDPVKKPKL AHCTFVRNRR HGLRLRSAGI
TLENVTLIDN ENAGLRFNPL LTRKTQRDVY SWLRRSDAAY QDTTIVDIPS RTVTEIQLTP
SSREQRRFIV SKASACDGSF AQDCAYELTI RTSLNFGRIG IQLVNRPSNS SDENVLIYDH
GQIARTISLR DNFIEFPFVT SGGVVKLHYS RSYGPARIAL LVFHLNNFEY LDPFLHMRAC
TIENNQYGVS AIHYSSFYRV DDGSILLRNR RTQLWFHKSN FTRNSQAVIW VNGPLLFDAS
QSSPVAVIEY FIDNCSVALN NGSIIETHRD LHRSANAFKW KVWQSTMLDN RDSGMSIALP
DPHYLDPNFE HRFELRETRF QDNENFHLEL SGYLAWVNIS SNNFTRNRAR DGHGLIKLTG
MEKELIMERN RWQYNRCRWV VSYDIKSHAL FKTKVAARVF YNYFFDNYFL SPEDEYAENW
PRSFAFGLFG LQQVDLHYNN FRNHLLDFEA VAGLKGAMLK TRANFSHNYW GRDSRAAIVQ
RIFDFDDWNI FSLAEYNPYF VTEERSLNWE WRPADAQLGT LDYEQPSVYD LHGRLFKSLT
MKRQREKWTI FPYWYKPDKP YYIRKDLTIM PGATLTIEPG VEVHIYPNVR ILVLGTLIAQ
GTFWDPIRLK PINLTDIQRP KQPTSATRWR RDAIYRMFPL LKRYDSFYQK FDVHLTDSLD
PSLGFLEIKN MTTGELVPVC DRQFTRRNAE VVCRELGMET RNVHVRIGPR WNYNPKLKIV
KSYPEPRQCY GHEGRLSDCA LRLSSDETLW RCVDSEHFVF IHCGKSVALD SNYVGHWGGL
MFGYQSAETH AAVGTNGGSV LRHVEIVGAG QAHNDSSAAV TVVRRGVVMD HVNVTNCSMH
GIDVVAPREQ VIFVKMNVTD NFGVGLRLLG VNSLAGSSIP PLFGEVPFPY HMFGILEFCS
VDKRILVEQR MFVYFKYDSY PVDCLKTFVS VNSAKQLEFK LLVANLYNVV DNAVRPDRIT
LYDGHHVDNG KILGIGIYGS SKLMLGQHAI RSETSELTVH LKTNAADGTY GFLAEVVTVP
APPEPSPLRQ ITLREVRFER NDRGAVRYAC TGDINPDVEV DFCSFNFNGY HLWGNFTTND
GALKMALYNT QNLRLENSMF FRNPGAVHIT ASSSSPSARL VGLVRNCAFG NNYNSESLVL
DGWDYQKFYV VNNFFGRNWA PYHDTVYVGQ VWANFTRNTF YNNTGTHIVH LGGYRDVSTE
FQIFYKNVLY DNIATGHGYH YPASYGYFGH KQPAYISSQL RKRRDVSQIH RTGSSSTSFE
WWANVGDQAE RYHSTVFAAS AQEKFELNLF NNPNNDFELT TAAKNPTDAY TGPLDARGNH
WGSTGTAAVA SGKIRDGNDY DYLIPVDHLP VIESNTSLID GFCPPGWFQA GYEEWKSFQS
CFLFVPGAVS YSVAQQFCKD QGAYMPFFRD QDRRLAPLAS KVDEMNREFA IPFERFIPHM
QTYETRFWIS SIVVPPEKCG YLSSSTGGIG IYNCEDVLPF VCEKGPKPYE EPLYWQPAGI
VAIIIAALLV LLVTVLGLLW WLKSKRRKEE FFERKSSLRA SIRSFKLAQA KLRQEQSIVE
VEREKARPPS PDLIEIAHRN LVLGSKSLES LNNSRIVVTT TTTTSPYTVS KLLSNSSLMK
LNNNESSYDS CTSSTIYQNG TFTTKGNCLR TSPSSSYCES AYRSDFSHSS ETSSLTGGTP
SFKSFRSKAA APPPPRPALP VRSAPLPNLT KKRDNLVRRN DTSVSNATTT TESCATCQTG
TTTLSYDTNC SVCREKLDEN RASSYFSSTC TDSNATLTVR DSASTCPPES TITQSSSPST
SDECSSTVRS PVRCRRAVGQ CSRDTLQSEN LQLYCEQPLS SDVYSDVPSI YGCRRSRAPI
CFKDRSAPDL TYTSTTAASA SRPDAVDSMY QSELAPMTSN PSSRSLSQLY SPWTPPDLDT
FSRSSQCSSA DEKPKPLETA M
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