ID   A0A0V1LFJ0_9BILA        Unreviewed;       495 AA.
AC   A0A0V1LFJ0;
DT   16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT   16-MAR-2016, sequence version 1.
DT   27-MAR-2024, entry version 23.
DE   SubName: Full=Acid-sensing ion channel 5 {ECO:0000313|EMBL:KRZ58202.1};
GN   Name=Asic5 {ECO:0000313|EMBL:KRZ58202.1};
GN   ORFNames=T02_4114 {ECO:0000313|EMBL:KRZ58202.1};
OS   Trichinella nativa.
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Enoplea; Dorylaimia;
OC   Trichinellida; Trichinellidae; Trichinella.
OX   NCBI_TaxID=6335 {ECO:0000313|EMBL:KRZ58202.1, ECO:0000313|Proteomes:UP000054721};
RN   [1] {ECO:0000313|EMBL:KRZ58202.1, ECO:0000313|Proteomes:UP000054721}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ISS10 {ECO:0000313|EMBL:KRZ58202.1};
RA   Korhonen P.K., Edoardo P., Giuseppe L.R., Gasser R.B.;
RT   "Evolution of Trichinella species and genotypes.";
RL   Submitted (MAY-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the amiloride-sensitive sodium channel (TC
CC       1.A.6) family. {ECO:0000256|ARBA:ARBA00007193,
CC       ECO:0000256|RuleBase:RU000679}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KRZ58202.1}.
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DR   EMBL; JYDW01000061; KRZ58202.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A0V1LFJ0; -.
DR   STRING; 6335.A0A0V1LFJ0; -.
DR   Proteomes; UP000054721; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0005272; F:sodium channel activity; IEA:UniProtKB-KW.
DR   Gene3D; 1.10.287.770; YojJ-like; 1.
DR   InterPro; IPR001873; ENaC.
DR   PANTHER; PTHR11690:SF301; AMILORIDE-SENSITIVE NA+ CHANNEL-RELATED; 1.
DR   PANTHER; PTHR11690; AMILORIDE-SENSITIVE SODIUM CHANNEL-RELATED; 1.
DR   Pfam; PF00858; ASC; 1.
DR   PRINTS; PR01078; AMINACHANNEL.
PE   3: Inferred from homology;
KW   Ion channel {ECO:0000256|RuleBase:RU000679};
KW   Ion transport {ECO:0000256|RuleBase:RU000679};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000054721};
KW   Sodium {ECO:0000256|ARBA:ARBA00023053};
KW   Sodium channel {ECO:0000256|ARBA:ARBA00022461,
KW   ECO:0000256|RuleBase:RU000679};
KW   Sodium transport {ECO:0000256|ARBA:ARBA00023201,
KW   ECO:0000256|RuleBase:RU000679};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW   ECO:0000256|RuleBase:RU000679};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|RuleBase:RU000679}.
FT   TRANSMEM        38..63
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        431..450
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
SQ   SEQUENCE   495 AA;  56693 MW;  AA5E698B87D661B1 CRC64;
     MPQIEVYPCK CNGNDAMTKF CEITTFHGLR DWHNADRFYL RVIWTVVLIG ALSAVAFGCY
     SILNEYISSP LAISYLVKEA DEDVHVPDVI VCPLNRFNGK YLKEKNVSDS LAWYMQLSFG
     LATKHPYMRK FMIENILSKT ETLKVEAQQM LDRLGMSFEM FVQEASFKCS DVLIQCQGPQ
     GIFSCCYDTS NATLMTFAGN CFRIPGVLQQ LPGYGMGISV VVHLPKDNFH IAPNNFNSDG
     ILVKLAERGT EIGHDMTFIP TGSYALLPLR ATKYDFINNP PYFECKPDDP SYGRVSCFDD
     CIYTVAEKKC NCSHVALGSQ RRYPPCDTDQ FLNCLQVELI KQLKEQWEEI FNICRSRCLL
     QCVRTQYTAQ VSYLKFPIDE TRRFVESDEQ WEEMKNSIVL DIYFERLGFT LIKHYPSMTE
     QGFLANIGGQ YSLWLGGSFL TLVQLILFIT RCIWDQLISK CPITNSKRLA NHGATSDVHK
     FYHFALFKSD PKMQI
//