ID   A0A0V1LS46_9BILA        Unreviewed;      1051 AA.
AC   A0A0V1LS46;
DT   16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT   16-MAR-2016, sequence version 1.
DT   24-JAN-2024, entry version 14.
DE   RecName: Full=Vacuolar protein sorting-associated protein 52 homolog {ECO:0000256|ARBA:ARBA00017083};
GN   Name=VPS52 {ECO:0000313|EMBL:KRZ62199.1};
GN   ORFNames=T02_14117 {ECO:0000313|EMBL:KRZ62199.1};
OS   Trichinella nativa.
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Enoplea; Dorylaimia;
OC   Trichinellida; Trichinellidae; Trichinella.
OX   NCBI_TaxID=6335 {ECO:0000313|EMBL:KRZ62199.1, ECO:0000313|Proteomes:UP000054721};
RN   [1] {ECO:0000313|EMBL:KRZ62199.1, ECO:0000313|Proteomes:UP000054721}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ISS10 {ECO:0000313|EMBL:KRZ62199.1};
RA   Korhonen P.K., Edoardo P., Giuseppe L.R., Gasser R.B.;
RT   "Evolution of Trichinella species and genotypes.";
RL   Submitted (MAY-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the VPS52 family.
CC       {ECO:0000256|ARBA:ARBA00008180}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KRZ62199.1}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; JYDW01000011; KRZ62199.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A0V1LS46; -.
DR   Proteomes; UP000054721; Unassembled WGS sequence.
DR   GO; GO:0005794; C:Golgi apparatus; IEA:UniProtKB-KW.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   InterPro; IPR028054; DUF4481.
DR   InterPro; IPR007258; Vps52.
DR   InterPro; IPR048361; Vps52_C.
DR   InterPro; IPR048319; Vps52_CC.
DR   PANTHER; PTHR14190; SUPPRESSOR OF ACTIN MUTATIONS 2/VACUOLAR PROTEIN SORTING 52; 1.
DR   PANTHER; PTHR14190:SF7; VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 52 HOMOLOG; 1.
DR   Pfam; PF14800; DUF4481; 1.
DR   Pfam; PF20655; Vps52_C; 1.
DR   Pfam; PF04129; Vps52_CC; 1.
PE   3: Inferred from homology;
KW   Golgi apparatus {ECO:0000256|ARBA:ARBA00023034};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Protein transport {ECO:0000256|ARBA:ARBA00022927};
KW   Reference proteome {ECO:0000313|Proteomes:UP000054721};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius};
KW   Transport {ECO:0000256|ARBA:ARBA00022448}.
FT   TRANSMEM        157..175
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        181..203
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          450..600
FT                   /note="Vps52 coiled-coil"
FT                   /evidence="ECO:0000259|Pfam:PF04129"
FT   DOMAIN          617..928
FT                   /note="Vps52 C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF20655"
SQ   SEQUENCE   1051 AA;  120844 MW;  89746722EB4E11AF CRC64;
     MRCNDDDDDF GIVAGCERTM STNVVVDHPN EDVVEMLNAN SMEQWKKDPS AGDVAEIEVT
     VQNVNPLAAS SEQQDESNRP TTTTIGTPLE NGITIVVVMP LKLSCKMLSY TKFDPNHVPR
     AILSSKLSIT VEDYVTAMEL LTNDFRFRLY TVFHQRIIFA WLIASLIVML CVLFSNARGL
     VLFALSLSWS FVIGLGTLLC VIFERMLDQS LSACVATVNR FLVRHNLLLC VDDRGKFSCH
     KIAIVFLYFN LDQCILEVAK NVEKIGLKLP RQQHHLSIPT TPSVSSQVDI VAAPTTAQNK
     ENAKRLILQH TQRYCRDLIR QGINLPVVRF QDQTDDMSIT FCLLIFEKIM STEKDNPAAG
     IISDKTTAVD GELLSEILGM GIDLREYAKD VQKQLKSVEA DAIQEFVEQA ENIATLHNEI
     RNCDKILNVI NLFYLHFSFS YLLKSPFLCL QQMESMLTAF QSDLGNISNE IQSLQEQSVK
     MSVKLKNRQA VRGELSQFID EIVVPEVMIK TIIDEPVSER LFLEQLHELQ HKIAFVKQQA
     FREALSCVEV EGLLENLRLK ATEKTRDFLL KRIYQFRKPM ANYPVTQGTL LKYRFYFEFI
     LSNDRYVAKE IRDEYVNTTS KIFYTYFKTY ASRLMKLQLD DVATKDDLLG SDDSTKMVNM
     FSTRPNVRNR ATVFSLGSRM SVLKEDLEAP IIVPHAADQN KQKFQFEVLF RSLLYAVLDH
     ACREYFFLCD FFLVSGQHSV DMFDQVFSKA LLIVTNACDA NMANCFDCIA LLLCIHIVYR
     YQAIGRQRGL PVLEKFWEQL LLELWLRFEQ ILTAHLTSMR DLDVKRLAPL DSRPHFIIRR
     YGEFFAALAA VNADLPDEKL QQYLYRLENE VAHLLARAMH EFKSIRERTI FLINNYDLIV
     SVLMEKLPGE SIDSQESSKR LQAYITEYAE LLLTTHFGSL VNFVYQAESL IEQGMQEKLK
     DNSANNVRNV VKTFNNDWKK NIEQINQEVM SSFSNFRVGT AILQKTFSQL IQYYHRLHKV
     LAMPTLNHPA RNELVNIHNL MVEVKKYKPM F
//