ID A0A0V1LSE0_9BILA Unreviewed; 2733 AA.
AC A0A0V1LSE0;
DT 16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT 16-MAR-2016, sequence version 1.
DT 22-FEB-2023, entry version 25.
DE SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:KRZ62422.1};
GN Name=PCLO {ECO:0000313|EMBL:KRZ62422.1};
GN ORFNames=T02_2486 {ECO:0000313|EMBL:KRZ62422.1};
OS Trichinella nativa.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Enoplea; Dorylaimia;
OC Trichinellida; Trichinellidae; Trichinella.
OX NCBI_TaxID=6335 {ECO:0000313|EMBL:KRZ62422.1, ECO:0000313|Proteomes:UP000054721};
RN [1] {ECO:0000313|EMBL:KRZ62422.1, ECO:0000313|Proteomes:UP000054721}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ISS10 {ECO:0000313|EMBL:KRZ62422.1};
RA Korhonen P.K., Edoardo P., Giuseppe L.R., Gasser R.B.;
RT "Evolution of Trichinella species and genotypes.";
RL Submitted (MAY-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KRZ62422.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; JYDW01000009; KRZ62422.1; -; Genomic_DNA.
DR Proteomes; UP000054721; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:InterPro.
DR GO; GO:0031267; F:small GTPase binding; IEA:InterPro.
DR GO; GO:0006887; P:exocytosis; IEA:InterPro.
DR CDD; cd00992; PDZ_signaling; 1.
DR Gene3D; 2.30.42.10; -; 1.
DR Gene3D; 2.60.40.150; C2 domain; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR000008; C2_dom.
DR InterPro; IPR035892; C2_domain_sf.
DR InterPro; IPR001478; PDZ.
DR InterPro; IPR036034; PDZ_sf.
DR InterPro; IPR039032; Rim-like.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR12157:SF21; RAB3 INTERACTING MOLECULE, ISOFORM F; 1.
DR PANTHER; PTHR12157; REGULATING SYNAPTIC MEMBRANE EXOCYTOSIS PROTEIN; 1.
DR Pfam; PF00168; C2; 1.
DR SMART; SM00239; C2; 1.
DR SMART; SM00228; PDZ; 1.
DR SUPFAM; SSF49562; C2 domain (Calcium/lipid-binding domain, CaLB); 1.
DR SUPFAM; SSF50156; PDZ domain-like; 1.
DR PROSITE; PS50004; C2; 1.
DR PROSITE; PS50106; PDZ; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000054721}.
FT DOMAIN 2345..2434
FT /note="PDZ"
FT /evidence="ECO:0000259|PROSITE:PS50106"
FT DOMAIN 2523..2649
FT /note="C2"
FT /evidence="ECO:0000259|PROSITE:PS50004"
FT REGION 145..224
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 245..467
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 665..702
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1084..1105
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1156..1179
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1362..1383
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1395..1418
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2255..2281
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 1713..1740
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 156..197
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 198..213
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 245..270
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 323..349
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 368..437
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1156..1176
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 2733 AA; 302190 MW; C2638B247486088F CRC64;
MKCGDSKHFR MFVCVLVRRL RAEVPGIRTG AVNKDAAHWL VRIDRFTNVY RLLEWEFDWL
PPFPPAGSVE AAVIERFILP RQKKTRIKNL DEMFGKVFGG ITHAVSHTAS QLRTQVLAPQ
FNATVDPLAG LSEVERAHIL AVQRRAADED SKLSQQPMVL PRSTASTVDA TASLPLPSLA
PSTLPSRPSS ASSTETEGAD DTSDDDDDDS GPIPDLDQIG LSEVTPADMR LDGLAEIGQE
RLLTSQESIE EQPTIVVHSP STNSNGAVDE SDANELEREE EEDERQQQHA EEEHEEDSLD
ELEHYSSPES DTQDVVEPVV QIPGDQQNLQ LAATDAGDES PSSSGDEWNC EYAGESFTAP
IRKSIEIDEP TTTPQSNERP IYQTEPAASS PPPAADTTAS SLFNYDQTDP TEWTNVEPLL
LTQEIELSSN ETDQSVMNKA PGVEMDEEAS SQTFYGDESS NPFLDGASFA DDQAISELVP
VEEPDEEVDE EKLNNDNEQQ LVIDASADEQ LSTALAEPIP SSDDDRFGVD EKIISQAEKT
FATVADHADS FGISNIAAAA SSVVIERQTS RSLTETTSRS VKQPFDMPAA SQAKLQSANK
IASAALDGFG GKSLKNFGGL FSRPKVDFSS FATSVKKSTE AALKKATDSV ASSFSSSSVV
SMSQDSFNSN NQPCTVPPKS PSSSAINTDN ASVNSNKSSD QWSALEVDKA DNNNNNSSAV
MKSTAAAVVG KKGIQPSPVV SNTFRVSCNS DSTEDTGYSS RCSPEDEFYR VGSDGAQFLI
TYDSSRKLGV DTVKAPLSPR RRINPFIEDG IFSQRLITSV IVEQADDQLT KSFHVSGQKR
QLDIVEKVEP GEQEKFHLIA EQSFWSSEPL QSQQLFGEID GPQEISQAGK DSTPKIEEVE
TLPLPDESTP LKYPPQQSIA NSGADEIAKL FAVEDSAPDS SACTQMYDSS EVSSEQFDED
AQKRITEIES EFLLQNNQSA DSVEDWQMCP LCQMAEVHVR PDGVSINGQP CGNCGLTVCS
KCGHVVEQNG YGYVAYAIQI LPKLMVAGIV MVMPDRDAYA FCVYWFTTKS QAISEDDNSK
LTFEKSQEVD SDISDQASDS SDSYPDVVIE VPSSPVKQLD FDQEFSTSNS KQCYKVFRDI
EKHFMNNFDQ CDDTKHEGKV DHHDQQTGHS DKGNFETDPF RTVPISVGQS PTFEKLTEQA
SPSDAQLSIG EEIFGKIVPP EQSCPSTNSN NAQEDSIDYA QAMRYYNTQP FYIHRPGPVY
TILEDDEEVM ELNQDAISAS RPSTLSSSSS KSQLTSFSSP LANSYVGLDR PAQQMQTSSN
ASTEQLTSTV SSDVLVQHFF ATSTTSTTTT SITASKSHAL QSNSTFTPKP VRIAPPPPPP
SQYSISRDAK IEKSIHQETS NKPTGGRRHS ADVPLSTDVN DSVVSGSLNG TAFKPVHSSS
STLTILAGQK KSDTPSSSTV AVSFALPVVR TVDMDASDPS SRLPLYSAAS TLCTTSTTAS
ATTPITTNET DDDEAVVECS GTGPFVSRLK RSPAMLLNCI KNETDLRAGS LQTALQSTPT
SALTACSSTS YPSSRLIDSA IPTPTKVVSS TSCGDTLQSG KTFLNERLFF AQASPGEMGR
RKLPNIPKIA SNRHQQDVDE PLCNISWSAG PVCSSTTTVN GSGITGITGG SSYNNVISMP
SSWKNIGHTL RPQHSTPLAT NCRRLLPPTL ARVLLKQELR EALTKRLDKL EAAEIEANQR
EFVVGRYMAT GVYPQSAGVD SAPSVVRCGL SPEMVRGCVV HFDRSRYLSS IRQRESSKAE
FSNSYGQSSR YGSYGGEEQW NSSRFVRKKE SFVKKDDSVV LLFVKFCGSS SLQTKRNDFT
VQTSDVLERY KDASTQTVQQ SSETTNSGNF VRFKPKDDLL LSKHKNVGVS TSEGPTCRTI
STSTDEIDED RLMARRRSEG NKKWRNLNSK SFTYFSADDD FASRESRRSK IRREIARRRE
KFSSYEDLFN LPPHRADSTY RYMDDGMELN NYITPSLYSS NRFSGHYGSL PRIDRLYDYS
PMSRNALYDD EPSSFSASYP LRPYQKYDRL YRSDTAPFVD GQDSAFHRGN YGTLTWRDQK
PWFIDGQRSL SSSLPYLNNL YESLDSQPEC SFRGYSRGRR FGEAGTEQVN TPRSSSMLSH
YANYLHNDFL RRSSALDDGY GNLCEDRSTA KCMPYADSST EFNCRPSSVM EPIASRLPYD
KYDEPLNDCL SLHRCRTDAP METYPSTRDY CSMTAQQPTF NSRRRRSRRQ QDQEPLYSGV
KSAQYDADLK TQSYNPYLTD SSLQNASVEN HHRQRASSQI LLEEGKSTFR QASSPSSANI
KRLLLVRDVR DRSGHGIGMR VIGGKILPGS DGELVAYVAA VYKGGLVDLM EEVKEGDQIL
EWNGIKLTGK TYEEVQSIID NTEGEFEIVL RSDANLNQVY RLEEGPSSSL DKGYESDCCL
SNLAHPRLAK LALQRKTGLD QTNDRHCQGL DFGKASPCFS TTPRSRSPFT ANQQQNSLLA
QDLANEGLLK LRVCFDHTSD TLFVTVLCAA RLPNVDAKKR RPPNPFVKIY ILPERIVQNK
RRTKFIARSN NPVWNQTVVY KDLNLEQALS KMLEFTVWSY DRFKQNTFLG KVIINLSAAN
RWWKHDYTVI PFEVCISMVK MQLFIHLIAA LLFLFARGED DAVVEPTFAD LKNLIDLYAR
EMEAMNAFGT SRRLKTIPLR DPRFITRKLF KND
//
