ID A0A0V1LTD8_9BILA Unreviewed; 2408 AA.
AC A0A0V1LTD8;
DT 16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT 16-MAR-2016, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE SubName: Full=Filamin-A {ECO:0000313|EMBL:KRZ62752.1};
DE Flags: Fragment;
GN Name=cher {ECO:0000313|EMBL:KRZ62752.1};
GN ORFNames=T02_3889 {ECO:0000313|EMBL:KRZ62752.1};
OS Trichinella nativa.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Enoplea; Dorylaimia;
OC Trichinellida; Trichinellidae; Trichinella.
OX NCBI_TaxID=6335 {ECO:0000313|EMBL:KRZ62752.1, ECO:0000313|Proteomes:UP000054721};
RN [1] {ECO:0000313|EMBL:KRZ62752.1, ECO:0000313|Proteomes:UP000054721}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ISS10 {ECO:0000313|EMBL:KRZ62752.1};
RA Korhonen P.K., Edoardo P., Giuseppe L.R., Gasser R.B.;
RT "Evolution of Trichinella species and genotypes.";
RL Submitted (MAY-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the filamin family.
CC {ECO:0000256|ARBA:ARBA00009238}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KRZ62752.1}.
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DR EMBL; JYDW01000006; KRZ62752.1; -; Genomic_DNA.
DR STRING; 6335.A0A0V1LTD8; -.
DR Proteomes; UP000054721; Unassembled WGS sequence.
DR GO; GO:0043232; C:intracellular non-membrane-bounded organelle; IEA:UniProt.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0051015; F:actin filament binding; IEA:InterPro.
DR GO; GO:0030036; P:actin cytoskeleton organization; IEA:InterPro.
DR CDD; cd21230; CH_FLN_rpt2; 1.
DR Gene3D; 1.10.418.10; Calponin-like domain; 2.
DR Gene3D; 2.60.40.10; Immunoglobulins; 19.
DR InterPro; IPR001589; Actinin_actin-bd_CS.
DR InterPro; IPR001715; CH_dom.
DR InterPro; IPR036872; CH_dom_sf.
DR InterPro; IPR044801; Filamin.
DR InterPro; IPR017868; Filamin/ABP280_repeat-like.
DR InterPro; IPR001298; Filamin/ABP280_rpt.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR014756; Ig_E-set.
DR PANTHER; PTHR38537:SF18; FILAMIN-A; 1.
DR PANTHER; PTHR38537; JITTERBUG, ISOFORM N; 1.
DR Pfam; PF00307; CH; 2.
DR Pfam; PF00630; Filamin; 16.
DR SMART; SM00033; CH; 2.
DR SMART; SM00557; IG_FLMN; 19.
DR SUPFAM; SSF47576; Calponin-homology domain, CH-domain; 1.
DR SUPFAM; SSF81296; E set domains; 19.
DR PROSITE; PS00019; ACTININ_1; 1.
DR PROSITE; PS00020; ACTININ_2; 1.
DR PROSITE; PS50021; CH; 2.
DR PROSITE; PS50194; FILAMIN_REPEAT; 20.
PE 3: Inferred from homology;
KW Actin-binding {ECO:0000256|ARBA:ARBA00023203};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000054721};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 21..39
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 83..189
FT /note="Calponin-homology (CH)"
FT /evidence="ECO:0000259|PROSITE:PS50021"
FT DOMAIN 212..315
FT /note="Calponin-homology (CH)"
FT /evidence="ECO:0000259|PROSITE:PS50021"
FT REPEAT 339..437
FT /note="Filamin"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00087"
FT REPEAT 445..535
FT /note="Filamin"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00087"
FT REPEAT 535..574
FT /note="Filamin"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00087"
FT REPEAT 702..753
FT /note="Filamin"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00087"
FT REPEAT 762..853
FT /note="Filamin"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00087"
FT REPEAT 854..950
FT /note="Filamin"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00087"
FT REPEAT 951..1048
FT /note="Filamin"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00087"
FT REPEAT 1049..1141
FT /note="Filamin"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00087"
FT REPEAT 1142..1240
FT /note="Filamin"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00087"
FT REPEAT 1241..1336
FT /note="Filamin"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00087"
FT REPEAT 1338..1433
FT /note="Filamin"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00087"
FT REPEAT 1463..1537
FT /note="Filamin"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00087"
FT REPEAT 1537..1636
FT /note="Filamin"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00087"
FT REPEAT 1633..1722
FT /note="Filamin"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00087"
FT REPEAT 1725..1817
FT /note="Filamin"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00087"
FT REPEAT 1842..1915
FT /note="Filamin"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00087"
FT REPEAT 1918..2036
FT /note="Filamin"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00087"
FT REPEAT 2038..2156
FT /note="Filamin"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00087"
FT REPEAT 2159..2250
FT /note="Filamin"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00087"
FT REPEAT 2284..2378
FT /note="Filamin"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00087"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:KRZ62752.1"
FT NON_TER 2408
FT /evidence="ECO:0000313|EMBL:KRZ62752.1"
SQ SEQUENCE 2408 AA; 264563 MW; B5AE3712989A74E6 CRC64;
LAAREQLFKS KSTGGILTNS SLLGCFYITA LLFLYIVVID NKFFNFCVIL HISNVNIIKY
PMVVNEEMDL EAIQSRDKAK WKTIQQNTFT RWVNERLKMV DCSVNNLETD LTDGLLLIRL
LEVLSKKKLP RYNKKPNFRS QRLENVSVAL SFLETVERIK LVNIDSSDIV DGRLKLILGL
IWTLILHYSI DAQIWDNEKN QQNQENKHKL PIPPKQRLLD WLNSKIPGFH LTNLTTQWSD
GRPLGALVDS LAPGLCPEWS MWKAANALKN TTTAMDLAEK WLVIPKLIEP EEFINPDVDE
MSMMTYLSQY PNAKLQPGAP IGSSVVGKTD SNNFEYPVTK TKQILQIKAS GPGLQSGVTC
GKTTHFDIYM AGGDEKKFAI QILNPNGKSD SVNQRFRRLS GDMLRCEYTP DMVGMHTINI
FYDDHSVLNN NPYEVWVASE SFEWKVFGRG IQNSGIRVGD KVDVRILCNG DANASLVEMI
VKHSDGSIVP IHRKNTSIRP LKVEGIYQPI QAGLHIVQIK YDGKDFPSSP FEVMVDSEMT
SKIRAFGPGL QSGVVNRPCK FTVETNGERC GLGKNLPVKH KQWGHADAGL NVVCVCERCL
SQICWHRSSV LEFCLRRIRQ SRQTTNPKHE AVSITVPPTN STPPKLFNSG NASCNIPASA
ASWQTEARFS LERRPEGMDM KWKCSISTIN NELCHCNYRG FSVDGPSKAE LTCHDNGDGS
AEICYIPKAC GEYAIHVLTN DVNISGSPYM VEIGESHLGC IPELVKCSGA GISEYGHVCG
QRSTFTVDAS RAGDSAVKIF AMDSDGMEMN IQQKTIANNV YSCSFVPESC KRHWIMVTFD
DQSVPGSPFK IHVSEQTNPN LVRMYGPGLE ESVRTKDRNH FFVDCADAGP GKVEVCMKNH
ADGSPVDVQI SDCGNGSYTV YYKVNKPGQY DIYVRFAGSP IPGMPYKVQV KPHVDLSSVV
IRGLEERVFI NSISEFTVDT TALTKTISNA EVSCTIRSPD GNMARCRVKN EKDGTYRIFY
STIVEGKHEL QVSYDDVPLT AQPLLVHAVD GHDETRCKVQ GAGLKAGLVG IPCRFRVDTK
GAGSGKLNIA IEGPSESTIS TANNLDGSCT VEYVVSKAGV YKISVTFAEK HIPGSPFTAL
IEPLLDPNLV RAWGPGLESK NCRFDLPLHF WVDTTRSGSA QLQVLVDSEC GAAPKQPEIV
EQAHGVYKVT YYAPEVDSNC KVHILYGGKE ISNSPYYMRV LPKCEAKKVK VRGCGLENFY
YVSDPVTLSV DISEAGYGAL QMMIKDPEGL PVSTKHTEKG TYLDKFTFIP DIAGTYDISI
KYGDEPVLNS PFALRILPVG GDFSKCQITE GRFETATVGE EQCIKVSTDP AGRGRVTCQI
LSAEPPTKIV NVVIEQHDDF CLLFYTLPNP GLYRITVRYG GQILQKGQWF IRGELSRRGS
VGETLIATPV VVSRGIAEDN SAEAEFSEKS WTFALPGTGR LTAKVVMPSK KTDIPIIRDN
ADGSVSVKYQ PSEVGLHELQ IKHDGLHVPG SPFSFHVGQV DDGYVTAYGN GLSFGIAGEP
AQFTVCAREP RGGSSILASG GLSVKIEGPA KADVKCHDNK DGTCSITWIP PAPGEYTVHI
QYAGKTIEGS PFKATVSGEG RKRAQISVGS TSEVSIKVTD PDVSVLSASI KSPSGIEEPC
LTRKLDSGNL GVSFTPREPG EHLVTVKKRG KLIHGSPFRI TVNKADVGDA SKVKVTGAGT
SQAITQEFNS FQLDTRQAGY GGVSVSLEGP SRCEIKYEDN KDKTCKIFYK PFEPGLYVLN
VKFADHHVPG SPFTLHCEGK GVGTVTETIE QTIPASPCVM PGDDCHVSLK IPGSSAIDLT
ASVMNPEGVI EDVELCEDSE EIYLIRFTPQ MLGVHTLSVL RHGQHIAGSP FQYTVGPFQD
SGTHKVHAGG PGLISGEVNM PCFFSIYSRE AGAGTLQIYI EGPSKAKLEY HEYRTGDGYI
SYCVTKPGDS AYRFLLLLLE LSSRTAMLWF FCSGDYNVAI KFNEKHIPDS PFKVYISSPT
GEARKLEVCS FPDSYGLAVN KPVTFTLVTH GAEGNLDAKV FSPSGATDDC FITPIEERGK
KYCSVAYFFN SQNICIVLYN TESYAIRFVP KEIGNHYLHI TLDGIHMKDS PFRFRAGPKG
EVDPIGVTVI GEGLRSGITG HKCEFTINTC HVGPGNLQIQ LDGPSKATLD AYDVEIGYKV
RYTPLAPGDY FVTIKYNGIH IPGSPFKINV TGQHLGGSGI NESSKVNINT VSKSSEGAAM
QVPKYYGDAS LVVCQGAGLK KAFASRQNIF NVDCSRAGQD LLFVCVMTQK GPAEEMHIKH
VGRGVFHINY MVRERGTCFV HVLYGNKHVP VYPFILSASN NWCNASKMMN DFEFRIEMTA
NEEKKKSK
//
