ID   A0A0V1LTH1_9BILA        Unreviewed;       763 AA.
AC   A0A0V1LTH1;
DT   16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT   16-MAR-2016, sequence version 1.
DT   27-MAR-2024, entry version 18.
DE   SubName: Full=Twinkle protein, mitochondrial {ECO:0000313|EMBL:KRZ62700.1};
GN   ORFNames=T02_2772 {ECO:0000313|EMBL:KRZ62700.1};
OS   Trichinella nativa.
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Enoplea; Dorylaimia;
OC   Trichinellida; Trichinellidae; Trichinella.
OX   NCBI_TaxID=6335 {ECO:0000313|EMBL:KRZ62700.1, ECO:0000313|Proteomes:UP000054721};
RN   [1] {ECO:0000313|EMBL:KRZ62700.1, ECO:0000313|Proteomes:UP000054721}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ISS10 {ECO:0000313|EMBL:KRZ62700.1};
RA   Korhonen P.K., Edoardo P., Giuseppe L.R., Gasser R.B.;
RT   "Evolution of Trichinella species and genotypes.";
RL   Submitted (MAY-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KRZ62700.1}.
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DR   EMBL; JYDW01000007; KRZ62700.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A0V1LTH1; -.
DR   Proteomes; UP000054721; Unassembled WGS sequence.
DR   GO; GO:0043139; F:5'-3' DNA helicase activity; IEA:InterPro.
DR   GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR   GO; GO:0016787; F:hydrolase activity; IEA:InterPro.
DR   GO; GO:0003697; F:single-stranded DNA binding; IEA:InterPro.
DR   GO; GO:0006260; P:DNA replication; IEA:InterPro.
DR   CDD; cd01122; Twinkle_C; 1.
DR   Gene3D; 3.40.50.1820; alpha/beta hydrolase; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   InterPro; IPR029058; AB_hydrolase.
DR   InterPro; IPR013094; AB_hydrolase_3.
DR   InterPro; IPR007694; DNA_helicase_DnaB-like_C.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR027032; Twinkle-like.
DR   PANTHER; PTHR12873; T7-LIKE MITOCHONDRIAL DNA HELICASE; 1.
DR   PANTHER; PTHR12873:SF0; TWINKLE MTDNA HELICASE; 1.
DR   Pfam; PF07859; Abhydrolase_3; 1.
DR   Pfam; PF03796; DnaB_C; 1.
DR   SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   PROSITE; PS51199; SF4_HELICASE; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000054721}.
FT   DOMAIN          272..476
FT                   /note="SF4 helicase"
FT                   /evidence="ECO:0000259|PROSITE:PS51199"
FT   REGION          1..26
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        9..26
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   763 AA;  86447 MW;  FE772D8DA084E40F CRC64;
     MKRTINKVDT MMNGYSGSSD EEAASDSPKT VVHTVWNQSI PINQMSLPKL TRLRQLLSLR
     HIQDSTFAKY NVRATANGDG LIFPRYTDRV ERVGVRQLKP SGLKIFRLTE NRNQPGIIEE
     TIPDSSTYVG FFGYHLVKSV DVETVLLFNE ADALSVHQAA GKVALAVHDQ YGPFQNQLLS
     LLTELIHVII WPPPEKYNRG KLLAKSLTST NCHLISPASC KNMRAADALA LPGKGRQLIT
     GVIKACERVE EKSLSTFDKL KELTKEYYYG YGSVSGICKW SRFSALNNYL KGFRLGELTL
     IGGGSACGKK TFLAEYALDI CCQNVPTLWC CLELPVGRLT ATLVEQDAFF EENTNQRSFD
     YWYEEISRLP MYFAKFDKVG FTKLKDIVEV IDRLAASKEV QHIVIDDVTA LQEWTLAKNG
     YDLNLIFSDL RRLAQNRNCH ITGSMLLSKF QNSKENNNAD TLQQNAINMQ AMKEADNVLV
     ICTKKLAQDI TDVEHENFLQ IWKTRRGGDL VLSNYIEMNF NRMTKCYTLT VGDRALPEGT
     WRLCILPLVL VVVISIVVNQ LYVPLPDRFA EREKMQVIET VARVLYMYPG KWLELFSTKW
     QLCWTRLVLN SLAWLCSYAY RSTEPQNVHI HTIMLDDVAA RVYIPDKVDT DAAIVYIHGG
     GFVLLNVDSY DLITRHLAKL TNMITVSIEY RLAPEHKFPA AIDDCERAIV YFLRHAHKLY
     SINSDKVVLV GDSAGGNLAA VVTQRLRNKR IRPVLKVSCL SIY
//