ID A0A0V1M7A6_9BILA Unreviewed; 683 AA.
AC A0A0V1M7A6;
DT 16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT 16-MAR-2016, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE SubName: Full=Heparan sulfate 2-O-sulfotransferase 1 {ECO:0000313|EMBL:KRZ67697.1};
GN Name=HS2ST1 {ECO:0000313|EMBL:KRZ67697.1};
GN ORFNames=T10_474 {ECO:0000313|EMBL:KRZ67697.1};
OS Trichinella papuae.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Enoplea; Dorylaimia;
OC Trichinellida; Trichinellidae; Trichinella.
OX NCBI_TaxID=268474 {ECO:0000313|EMBL:KRZ67697.1, ECO:0000313|Proteomes:UP000054843};
RN [1] {ECO:0000313|EMBL:KRZ67697.1, ECO:0000313|Proteomes:UP000054843}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ISS1980 {ECO:0000313|EMBL:KRZ67697.1};
RA Korhonen P.K., Edoardo P., Giuseppe L.R., Gasser R.B.;
RT "Evolution of Trichinella species and genotypes.";
RL Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004606}; Single-
CC pass type II membrane protein {ECO:0000256|ARBA:ARBA00004606}.
CC -!- SIMILARITY: Belongs to the sulfotransferase 3 family.
CC {ECO:0000256|ARBA:ARBA00010569}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KRZ67697.1}.
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DR EMBL; JYDO01000188; KRZ67697.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0V1M7A6; -.
DR Proteomes; UP000054843; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0008146; F:sulfotransferase activity; IEA:InterPro.
DR Gene3D; 3.30.160.60; Classic Zinc Finger; 2.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR007734; Heparan_SO4_2-O-STrfase.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR005331; Sulfotransferase.
DR InterPro; IPR036236; Znf_C2H2_sf.
DR InterPro; IPR013087; Znf_C2H2_type.
DR PANTHER; PTHR12129; HEPARAN SULFATE 2-O-SULFOTRANSFERASE; 1.
DR PANTHER; PTHR12129:SF17; HEPARAN SULFATE 2-O-SULFOTRANSFERASE 1; 1.
DR Pfam; PF03567; Sulfotransfer_2; 1.
DR SMART; SM00355; ZnF_C2H2; 3.
DR SUPFAM; SSF57667; beta-beta-alpha zinc fingers; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS00028; ZINC_FINGER_C2H2_1; 3.
DR PROSITE; PS50157; ZINC_FINGER_C2H2_2; 3.
PE 3: Inferred from homology;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW Metal-binding {ECO:0000256|PROSITE-ProRule:PRU00042};
KW Reference proteome {ECO:0000313|Proteomes:UP000054843};
KW Transferase {ECO:0000313|EMBL:KRZ67697.1};
KW Zinc {ECO:0000256|PROSITE-ProRule:PRU00042};
KW Zinc-finger {ECO:0000256|PROSITE-ProRule:PRU00042}.
FT DOMAIN 67..95
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 96..123
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 124..152
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
SQ SEQUENCE 683 AA; 78354 MW; 474EC15DBD15D535 CRC64;
MADTAVVPMP MVQEECSPGR QSISLQNLME NSQSKVNNGK MENRSSYNPK TGIGMVSSED
LGDILDMQCE LCLETFRNKK ERLFHMRNVH DAEKPYRCRL CGKSFPYWSS LHNHRRLHLP
DRPFVCSICS SCFRWKFCLK QHIIASHSTE KGKAVESFTQ KVMKEEMTTM GGYETRSISN
DSMEEFSSPI YPDSLSPLHK TVEKVSHAGS FVSEIPTVSS SVVPTAVLTK TDVNQKTVLP
KDSQMKIRIR IDSKGNKLNL ISMKPKVKKC SISPCAPSEQ NSGQNWQFDK NEEMNDVAAI
QATNNFVPSL QAKQSDVRVG SRIEKLASRL RRSFEVGDEP VNQMKAKRTS DASVQTFSDE
SSGCSGAFDA DAFLVEICLD HRCSIRCGKN PSLAEGSSNE WNLQNAVFLY NRIPKTGSTS
LMGIIYELCQ KNSFHVIHLN MSKNSHLMTP WDQVHFAGNF SNWTQRKPAF YHGHVAYIDF
TKFGMRNPIY LNVVRDPLER MISYYYFLRY GDDFRPHLSR KRKGNNETFD ECVKRKGRDC
DPANLWLQVP FFCGHHADCW IPGNVWALER AKNTLLDHYM LVGVSEELQD FIELLELIFP
DFFSGATVIY SQGRKSYLRK TVKKIPPSEQ TLAQIRQSPI WKMEQNFYEF ARRQFHFLKM
IKTRLGGKRE TGYHYEKVKP TFI
//
