ID A0A0V1M9W1_9BILA Unreviewed; 1819 AA.
AC A0A0V1M9W1;
DT 16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT 16-MAR-2016, sequence version 1.
DT 27-MAR-2024, entry version 18.
DE RecName: Full=Vacuolar protein sorting-associated protein 53 homolog {ECO:0000256|ARBA:ARBA00014103};
GN ORFNames=T10_7716 {ECO:0000313|EMBL:KRZ68616.1};
OS Trichinella papuae.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Enoplea; Dorylaimia;
OC Trichinellida; Trichinellidae; Trichinella.
OX NCBI_TaxID=268474 {ECO:0000313|EMBL:KRZ68616.1, ECO:0000313|Proteomes:UP000054843};
RN [1] {ECO:0000313|EMBL:KRZ68616.1, ECO:0000313|Proteomes:UP000054843}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ISS1980 {ECO:0000313|EMBL:KRZ68616.1};
RA Korhonen P.K., Edoardo P., Giuseppe L.R., Gasser R.B.;
RT "Evolution of Trichinella species and genotypes.";
RL Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Endosome membrane
CC {ECO:0000256|ARBA:ARBA00004481}; Peripheral membrane protein
CC {ECO:0000256|ARBA:ARBA00004481}. Golgi apparatus, trans-Golgi network
CC membrane {ECO:0000256|ARBA:ARBA00004150}; Peripheral membrane protein
CC {ECO:0000256|ARBA:ARBA00004150}. Membrane
CC {ECO:0000256|ARBA:ARBA00004170}; Peripheral membrane protein
CC {ECO:0000256|ARBA:ARBA00004170}.
CC -!- SIMILARITY: Belongs to the VPS53 family.
CC {ECO:0000256|ARBA:ARBA00008628}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KRZ68616.1}.
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DR EMBL; JYDO01000159; KRZ68616.1; -; Genomic_DNA.
DR Proteomes; UP000054843; Unassembled WGS sequence.
DR GO; GO:0005829; C:cytosol; IEA:GOC.
DR GO; GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0000938; C:GARP complex; IEA:InterPro.
DR GO; GO:0042147; P:retrograde transport, endosome to Golgi; IEA:InterPro.
DR Gene3D; 3.40.50.11980; -; 2.
DR Gene3D; 1.10.357.110; Vacuolar protein sorting-associated protein 53, C-terminus; 1.
DR InterPro; IPR031595; PRORP_C.
DR InterPro; IPR039766; Vps53.
DR InterPro; IPR031745; Vps53_C.
DR InterPro; IPR038260; Vps53_C_sf.
DR InterPro; IPR007234; Vps53_N.
DR PANTHER; PTHR12820:SF0; VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 53 HOMOLOG; 1.
DR PANTHER; PTHR12820; VACUOLAR SORTING PROTEIN 53; 1.
DR Pfam; PF16953; PRORP; 2.
DR Pfam; PF16854; VPS53_C; 1.
DR Pfam; PF04100; Vps53_N; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Endosome {ECO:0000256|ARBA:ARBA00022753};
KW Golgi apparatus {ECO:0000256|ARBA:ARBA00023034};
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Reference proteome {ECO:0000313|Proteomes:UP000054843}.
FT DOMAIN 273..407
FT /note="PRORP"
FT /evidence="ECO:0000259|Pfam:PF16953"
FT DOMAIN 508..869
FT /note="Vps53 N-terminal"
FT /evidence="ECO:0000259|Pfam:PF04100"
FT DOMAIN 1114..1198
FT /note="Vps53 C-terminal"
FT /evidence="ECO:0000259|Pfam:PF16854"
FT DOMAIN 1562..1698
FT /note="PRORP"
FT /evidence="ECO:0000259|Pfam:PF16953"
FT COILED 530..582
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 1819 AA; 209238 MW; 709911BEFAE258D6 CRC64;
MFVLALRRFA VHLGCFRRRF ESKKQFTCYL LRFCSASTGM DPILRMDTKS KVLYQTIHSY
IVHNDIVSND DWHYFRRMLL ESSDKQNTVD CAVLKVLEQN CYFDLGMSYI SYLFGTGLDN
PITIKQAVYF LEQCYVKSFE NFESRMANEL LDHILVMEKS FPNFFTYQKA IVLCLCGDFD
ELSSMWSNVL DGPTKCRLMS TVFIAACRYR CIGWIWSLTV KSPFTLSASC HVEMAKYLEE
TIFNGGESTS ISALDSYVDF YDRSQCFTFD ESAVESFKNY FARFLNINGP FDVVVHGCNI
AYLGDPASND VQIRRITRLV RVLRFELNFK NILVVGREHF MRFAADPLRT MAKLFSVSNL
TTDDMYVITA AMNSGKHCYV VSKDLVQMHC HKLMPLNQNY FYRWRDMRLM FSEQTEPNCP
RHKMLQFPKP LCNNVERNFM GSRYHFLYRP HEADEFDHCH VKNVIDSEEQ KPKWLRMMDL
QTPVRFSETV QSALDSVADP EDPFNKPDFC VLSYINHLFP TEPRHVGQVM ADVQRQINQV
DQEISEILEK QSVAQLDSEA LLQQTKQAMR ELFAQIMDIK RQTDMSETTV KEITHDIRQL
DLAKKNLTAS ITTLNHLHML VSGLESLESF VKTKNFRDIS NLLPGIQNVL EHFSQYMTVP
QIKALSDQVN SIRAELADLT TAELKRYFSG GFKKASGQQS VPIEDVCLVL SVLDQAVREG
LIGWLIDQQL AEYKILFDDT QDDAWLDKID LRFSWFRDCL IEFERKHAGL LPAEWDVACK
FAAEFFQLTG SMLDQVMEKR CVEMDAKLLL FAVQRAANFE ALMARRFPGR GEALFQGTLV
GRFQKRMSIY TASLDKTLND LIDQLVGKFK EVGPPSAEYG CAAVAIPTSS DLFVFYKKCI
QQLLQLGMNA NILVDLSRLF KKYLHEYAQR CLTGVLPKIA SSHSTTTAGL LQSFLKEGDM
PRLSNDEIYL VCCVLITAEF CAETSHQLQE KLKEKAGDLA MHEAFDFTNE REMFHGVVSS
CVQVLVQDLE SACEPALQTM TKMQWANVDS VGDESRYVAS IRQHGRQCVV RIRDCLGQAR
KYFMQFCFRF VNAFVPKFIN AILRCRPVSV TGAEQLLLDT HALKTELVNL PVLESAAGRK
PPEAFTKLVI KGMNKAEMIL KLVMAPVDDP GTFVEHYINF LPESDVVEFQ KILDMKSVRK
NEQTTIMDIF REKKAALDIN NDLSAEGGVA CDAVLSSGDN SNLDSRIRKL EKLSYCGHEP
AGHQFSFPPE SHGATLRWKR HSPVASGGIA PSAEHFYRKY RFINAQIKSR LKLLESSFAT
TQILFCLNCM DPILCMDTIS KALYQTIHSY IVHNDIVSYE DWDYFRRMLL DSSDKQNTVD
CAVLKVLEQN CYFDLGMFYI SYLFDTGLDN PTTIKQAVHF LEQCYLKSFE NFDSKVANEL
LDHILIMEKS FPNFFTYQKA IVLCLCGEFD KFSSMWSNVL DSPTKCRLMS TIFIAACRYL
CIGWIWPLTM KCPFTLSASC HVEMAKYLVK TICSSDEWTS KGALDQYVDF YDRSQCFTFD
ESAVESFKNY FARFLNINGP FDVVVHGCNI AYLGDPASND VQIRRITRLV RVLRFELNFK
NILVVGREHF MRFAADPLRT MSKLFSVSNL TTDDMYVITA AMNSGKHCYV VSKDLVQMHC
HKLMPLNQNY FYRWRDMRLM FSEQTEPNCP RHKMLQFPKP LCNNVERNFM GSSYHFLYRP
NEADEFDHCH VKKTIMSDSD EQKPKWLGMI DLQTPVRFSE TVQSALDSVA DPEDPFNKPD
FCVLSYINHL FPTDPSPKV
//
