ID A0A0V1MAG0_9BILA Unreviewed; 1478 AA.
AC A0A0V1MAG0;
DT 16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT 16-MAR-2016, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE SubName: Full=Cholecystokinin receptor {ECO:0000313|EMBL:KRZ68650.1};
DE Flags: Fragment;
GN Name=cckar {ECO:0000313|EMBL:KRZ68650.1};
GN ORFNames=T10_7639 {ECO:0000313|EMBL:KRZ68650.1};
OS Trichinella papuae.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Enoplea; Dorylaimia;
OC Trichinellida; Trichinellidae; Trichinella.
OX NCBI_TaxID=268474 {ECO:0000313|EMBL:KRZ68650.1, ECO:0000313|Proteomes:UP000054843};
RN [1] {ECO:0000313|EMBL:KRZ68650.1, ECO:0000313|Proteomes:UP000054843}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ISS1980 {ECO:0000313|EMBL:KRZ68650.1};
RA Korhonen P.K., Edoardo P., Giuseppe L.R., Gasser R.B.;
RT "Evolution of Trichinella species and genotypes.";
RL Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651};
CC Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the G-protein coupled receptor 1 family.
CC {ECO:0000256|RuleBase:RU000688}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KRZ68650.1}.
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DR EMBL; JYDO01000158; KRZ68650.1; -; Genomic_DNA.
DR EMBL; JYDO01000158; KRZ68654.1; -; Genomic_DNA.
DR Proteomes; UP000054843; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0004930; F:G protein-coupled receptor activity; IEA:UniProtKB-KW.
DR GO; GO:0008641; F:ubiquitin-like modifier activating enzyme activity; IEA:InterPro.
DR CDD; cd14993; 7tmA_CCKR-like; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR Gene3D; 1.20.1070.10; Rhodopsin 7-helix transmembrane proteins; 1.
DR InterPro; IPR009126; Cholcskin_rcpt.
DR InterPro; IPR000276; GPCR_Rhodpsn.
DR InterPro; IPR017452; GPCR_Rhodpsn_7TM.
DR InterPro; IPR000594; ThiF_NAD_FAD-bd.
DR InterPro; IPR035985; Ubiquitin-activating_enz.
DR PANTHER; PTHR24238:SF76; CHOLECYSTOKININ-LIKE RECEPTOR AT 17D1-RELATED; 1.
DR PANTHER; PTHR24238; G-PROTEIN COUPLED RECEPTOR; 1.
DR Pfam; PF00001; 7tm_1; 1.
DR Pfam; PF00899; ThiF; 1.
DR PRINTS; PR01822; CCYSTOKININR.
DR PRINTS; PR00237; GPCRRHODOPSN.
DR SMART; SM01381; 7TM_GPCR_Srsx; 1.
DR SUPFAM; SSF69572; Activating enzymes of the ubiquitin-like proteins; 1.
DR SUPFAM; SSF81321; Family A G protein-coupled receptor-like; 1.
DR PROSITE; PS00237; G_PROTEIN_RECEP_F1_1; 1.
DR PROSITE; PS50262; G_PROTEIN_RECEP_F1_2; 1.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW G-protein coupled receptor {ECO:0000256|RuleBase:RU000688};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Receptor {ECO:0000256|RuleBase:RU000688, ECO:0000313|EMBL:KRZ68650.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000054843};
KW Transducer {ECO:0000256|RuleBase:RU000688};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU000688};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 52..76
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 97..119
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 131..149
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 170..195
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 215..240
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 362..384
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 67..414
FT /note="G-protein coupled receptors family 1 profile"
FT /evidence="ECO:0000259|PROSITE:PS50262"
FT REGION 257..285
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 257..275
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:KRZ68650.1"
SQ SEQUENCE 1478 AA; 169394 MW; F483FE72ECB8903D CRC64;
LRWLFANMDN VTTHEAPLSL VLVNLTVRTV NISPYEELPE PCQLIDSSGN KLLMVVFTII
FCLSVIGNSL VIVTIVQNRW MRTITNLFLL NMAISDLLLT LICMPPTLTA ILFQCFIWGQ
KMRWMCTLIS FLQPVSVAAN ANTLVAIALE RYYALCRPLH SRQWQTKSNV VRMMIIVWTA
SFTCSIPQAI VAEVIEIRPG QLNCRDNWPS GQAQLIYFIF LSLVLFIIPL IIMTMLYSLV
IRSLWLGIKL HSQQSEPSLL NSKSGTRQSS LDTTDQLIDE PDEKRTSKNG WATFKLTTCS
GFFFHNRPKT EPTAGVGSNG SNGANGESAI QSNRSRARLS GAFLRSTHIE KSLQTKKRVI
KMLAAIVVEF FICWMPFYTF YLVVIIRPAL FDASCYVTFL IMAYLSTCTN PITYCFMNSK
FRKAFLAAIG CHIKEDEKAN FRKSTGPKRR EAFRLPSVKP GDPLPSMQTL DEENLIRRLS
SNENYATAKQ SLTDAFMEIV EKPKSLTEDE AKVYDRQMRL WGVNGQMKIR GFSVILCGVH
DIGAEMAKNL ILSGIKQLTL VDDTVVNDER TSLLIKKNSI GMLRSEASRE VCQQFNPSVE
VKVESIQSLN ETLLEGYDLL VDANGNFKFS LHLHHMCSVS KVSYLCCTSM GVYSFYSMNC
FSSDEDKNFE VPTKALHLDD NGKNADVDRD IINLVNNKQF RSVKKCFVII CAKLLFEMKH
DRMLDFKRHP EDTDEFLAMC DKVKARVMDK SDVKIAKEDL INLTVRLPAL SSVLAGTASS
TVIDAALENP FPSKIVQLFR DFCAHFIVSK ECKFLQKFCH LIAIPSELFN HAVSVTTIQL
IDSHGNIHTL SFNAPDEDSI PFYNYYDANE AENNEEIIHI FHFYIQCKAL QMNFSEAKEF
KLHSRIHSVL SLNVCMHHCL STGSNWVFRA VVYYEEKKIC ELYTKNINGN SILSTEEQKM
IKLYNCFKDR ESERINNPEP LNIFFEELSK LYVILIIGLC FTTSEQTSFV AHFPDENLSC
LLELHHLRQN ETSLLEKLPV STLTDCIVAC YMQNQSGFCN TVYFSKSQLM CYFIKQQEDT
FESTDEEFRK KNLLDNEKIK KKSCNFDTLK SHVILHDVSL ICYLEQRSLK EAKNAIPFRN
LTSSSLFTCI FFCQQWYAFV HCNAVSFSLE TGNCILYHDY VPTLQRTSVE CSSTKFYSVI
LCMDISIEVI SIELIKGTNF NFECSTEITP EQRGILVEDF ETQSLRSSMS EWMEYVVNFG
SRSTFLTANL YEFFEICKIK EVDPKGIKNL TLHESYSRVN SLNTCLHKCR RAISEWPYRA
VHYSSEKKYC YIYVKSSGTS VNVTLEADEQ FVELQTCFTD RRSDRANNPD ALAFYIKSQG
EVCLVEFYEK NFLNHWRTIN YIMNVTNITE CLSWCRHYDN SDKCSAINFA IDGKCRLLKK
SHRRLSYRTL PKSVFGEILV CKPGCLTDEF QPYFQLKK
//
