ID A0A0V1MIF2_9BILA Unreviewed; 678 AA.
AC A0A0V1MIF2;
DT 16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT 16-MAR-2016, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE SubName: Full=Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 2 {ECO:0000313|EMBL:KRZ71402.1};
GN Name=PAPSS2 {ECO:0000313|EMBL:KRZ71402.1};
GN ORFNames=T10_6604 {ECO:0000313|EMBL:KRZ71402.1};
OS Trichinella papuae.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Enoplea; Dorylaimia;
OC Trichinellida; Trichinellidae; Trichinella.
OX NCBI_TaxID=268474 {ECO:0000313|EMBL:KRZ71402.1, ECO:0000313|Proteomes:UP000054843};
RN [1] {ECO:0000313|EMBL:KRZ71402.1, ECO:0000313|Proteomes:UP000054843}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ISS1980 {ECO:0000313|EMBL:KRZ71402.1};
RA Korhonen P.K., Edoardo P., Giuseppe L.R., Gasser R.B.;
RT "Evolution of Trichinella species and genotypes.";
RL Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- PATHWAY: Sulfur metabolism; sulfate assimilation.
CC {ECO:0000256|ARBA:ARBA00005050}.
CC -!- SIMILARITY: In the C-terminal section; belongs to the sulfate
CC adenylyltransferase family. {ECO:0000256|ARBA:ARBA00009290}.
CC -!- SIMILARITY: In the N-terminal section; belongs to the APS kinase
CC family. {ECO:0000256|ARBA:ARBA00007268}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KRZ71402.1}.
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DR EMBL; JYDO01000097; KRZ71402.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0V1MIF2; -.
DR UniPathway; UPA00097; -.
DR Proteomes; UP000054843; Unassembled WGS sequence.
DR GO; GO:0004020; F:adenylylsulfate kinase activity; IEA:UniProtKB-EC.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0004781; F:sulfate adenylyltransferase (ATP) activity; IEA:UniProtKB-EC.
DR GO; GO:0000103; P:sulfate assimilation; IEA:UniProtKB-UniPathway.
DR CDD; cd02027; APSK; 1.
DR CDD; cd00517; ATPS; 1.
DR Gene3D; 3.40.50.620; HUPs; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 3.10.400.10; Sulfate adenylyltransferase; 1.
DR HAMAP; MF_00065; Adenylyl_sulf_kinase; 1.
DR InterPro; IPR002891; APS_kinase.
DR InterPro; IPR025980; ATP-Sase_PUA-like_dom.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR015947; PUA-like_sf.
DR InterPro; IPR014729; Rossmann-like_a/b/a_fold.
DR InterPro; IPR024951; Sulfurylase_cat_dom.
DR InterPro; IPR002650; Sulphate_adenylyltransferase.
DR NCBIfam; TIGR00455; apsK; 1.
DR NCBIfam; TIGR00339; sopT; 1.
DR PANTHER; PTHR11055; BIFUNCTIONAL 3'-PHOSPHOADENOSINE 5'-PHOSPHOSULFATE SYNTHASE; 1.
DR PANTHER; PTHR11055:SF1; PAPS SYNTHETASE, ISOFORM D; 1.
DR Pfam; PF01583; APS_kinase; 1.
DR Pfam; PF01747; ATP-sulfurylase; 1.
DR Pfam; PF14306; PUA_2; 1.
DR SUPFAM; SSF52374; Nucleotidylyl transferase; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF88697; PUA domain-like; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Nucleotidyltransferase {ECO:0000256|ARBA:ARBA00022695};
KW Reference proteome {ECO:0000313|Proteomes:UP000054843};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 283..437
FT /note="ATP-sulfurylase PUA-like"
FT /evidence="ECO:0000259|Pfam:PF14306"
FT DOMAIN 446..668
FT /note="Sulphate adenylyltransferase catalytic"
FT /evidence="ECO:0000259|Pfam:PF01747"
SQ SEQUENCE 678 AA; 77158 MW; A1F2A89FB20AB7D8 CRC64;
MEFPLQLFNV MIPARKRIRL IFVSVYFECS AYVQPSSFSL LRAAWPAFVN ETSVQKTVCI
REMLFFLTKE SRATNITPQS HRVTREQRAQ ALGKYPNFRG CTIWFTGLSG SGKTTISFAL
EKVLCSVGLP AYGLDGDNMR HGICKNLGFS EEDREENIRR VAEVAKLFAD LGIIALASFI
SPFERDRRRA RKIHEDSGLI FIECFIDTPL EVCERRDPKG LYEKARVGKI LDFTGIDSAY
EVPENPELIL HAAEETVIQC VQRVLQYLHE RGIFPDEALM RLGAKVRELF VDESERLRLE
ASLSQMPTLS LEKIDLQWLQ VLSEGWATPL SGFMTETQYL QTLHFNQLIE ENTISQSIPI
VLPVTNEEKA KLENADLIAL CYNGHTMAIL LKPEFYPHRK EERCARQFGT CHLGHPTVKM
IMQAGDWLVG GEVKTLKPIK WNDGLDQYRL TPMEIRQRLV EMDADAVFAF QLRNPIHNGH
ALLMNDTKRT LISRGYKRPV LLLHPLGGWT KDDDVPLAVR MKQHQTLLEE GVLDPESTLL
AIFPSPMLYA GPTEVMWHAR ARMAAGIHFY IVGRDPAGIQ HPDTGDYLYD PTHGSKILSM
TPGLGDVEIL PFKVAAYNKL TQQMDYFDPS RKDEFDFISG SRMRKIAREG AQPPDGFMAP
KAWEVLANYY RSLQNTVQ
//
