ID A0A0V1MJD8_9BILA Unreviewed; 3229 AA.
AC A0A0V1MJD8;
DT 16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT 16-MAR-2016, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE SubName: Full=Vacuolar protein sorting-associated protein 13A {ECO:0000313|EMBL:KRZ71454.1};
GN Name=VPS13A {ECO:0000313|EMBL:KRZ71454.1};
GN ORFNames=T10_1393 {ECO:0000313|EMBL:KRZ71454.1};
OS Trichinella papuae.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Enoplea; Dorylaimia;
OC Trichinellida; Trichinellidae; Trichinella.
OX NCBI_TaxID=268474 {ECO:0000313|EMBL:KRZ71454.1, ECO:0000313|Proteomes:UP000054843};
RN [1] {ECO:0000313|EMBL:KRZ71454.1, ECO:0000313|Proteomes:UP000054843}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ISS1980 {ECO:0000313|EMBL:KRZ71454.1};
RA Korhonen P.K., Edoardo P., Giuseppe L.R., Gasser R.B.;
RT "Evolution of Trichinella species and genotypes.";
RL Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the VPS13 family.
CC {ECO:0000256|ARBA:ARBA00006545}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KRZ71454.1}.
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DR EMBL; JYDO01000096; KRZ71454.1; -; Genomic_DNA.
DR Proteomes; UP000054843; Unassembled WGS sequence.
DR GO; GO:0006869; P:lipid transport; IEA:UniProtKB-KW.
DR InterPro; IPR026847; VPS13.
DR InterPro; IPR026854; VPS13-like_N.
DR InterPro; IPR049424; VPS13_C.
DR InterPro; IPR031645; VPS13_DH-like.
DR InterPro; IPR031646; VPS13_extend_chorein.
DR InterPro; IPR031642; VPS13_mid_RBG.
DR InterPro; IPR009543; VPS13_VAB.
DR PANTHER; PTHR16166:SF93; INTERMEMBRANE LIPID TRANSFER PROTEIN VPS13; 1.
DR PANTHER; PTHR16166; VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN VPS13; 1.
DR Pfam; PF12624; Chorein_N; 1.
DR Pfam; PF21679; VPS13_C; 1.
DR Pfam; PF16909; VPS13_DH-like; 1.
DR Pfam; PF16908; VPS13_ext_chorein; 1.
DR Pfam; PF16910; VPS13_mid_rpt; 2.
DR Pfam; PF06650; VPS13_VAB; 1.
PE 3: Inferred from homology;
KW Lipid transport {ECO:0000256|ARBA:ARBA00023055};
KW Reference proteome {ECO:0000313|Proteomes:UP000054843};
KW Transport {ECO:0000256|ARBA:ARBA00022448}.
FT DOMAIN 3..116
FT /note="Chorein N-terminal"
FT /evidence="ECO:0000259|Pfam:PF12624"
FT DOMAIN 134..369
FT /note="Vacuolar protein sorting-associated protein 13
FT extended chorein"
FT /evidence="ECO:0000259|Pfam:PF16908"
FT DOMAIN 575..802
FT /note="VPS13 middle RBG modules"
FT /evidence="ECO:0000259|Pfam:PF16910"
FT DOMAIN 1148..1342
FT /note="VPS13 middle RBG modules"
FT /evidence="ECO:0000259|Pfam:PF16910"
FT DOMAIN 1982..2505
FT /note="Vacuolar protein sorting-associated protein 13 VPS13
FT adaptor binding"
FT /evidence="ECO:0000259|Pfam:PF06650"
FT DOMAIN 2816..2992
FT /note="Vacuolar protein sorting-associated protein 13 DH-
FT like"
FT /evidence="ECO:0000259|Pfam:PF16909"
FT DOMAIN 3086..3193
FT /note="Intermembrane lipid transfer protein VPS13 C-
FT terminal"
FT /evidence="ECO:0000259|Pfam:PF21679"
FT REGION 1349..1369
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1391..1424
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1409..1424
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 3229 AA; 363703 MW; 8C7F6174D188B708 CRC64;
MVFESFVTAL LNRFLGAYVE NLDASKMNFA IWSGNVALND LRLKASSLDE LNLSVKLKFG
FLEKLALKIP WQNLYTEPVV AEVEGLYLLA VPNAGIKYNA EKEEKMAIDA KLAELTRIEL
AKKQAVTAVQ EDTFTERMLS QVIKNLQVTI RNIHIRYEDC FSNVERRFAA GLTLHQLCFQ
TTDEDWKPCI LKELKKIIYK ATEMKSLSIY WNCSCQLLSN LDDFQQLKVA MEKGIAREGY
TPEEFYYILA PISIGAYLKL NTKPETDGTN FSVPKFFVAI EMEQLTLNIH KYQYQGILEF
LEAQEQFALN ATYRKFRPYG ISYRGHAKEW WKFAIDAIME TEVQRRARNW SWKHIKQHRE
LLKEYRAAWV EKLTNKNISA EKIAKIQLAE KELDLFNLNI ARQAAEIEIR RRGLKLIEEQ
GGWVSWVKSF WNSDQKQEQQ NDLTDITTQF EKAMTKEEKA KLYEAIGYQE NQTPTVYPKE
FVDIDIRFKL GCFTVVVLDT NETGSRLGVL KMCLQSVEAS FKQRRSANAF LLEGEVGVFK
ITGVGSAQDV AERSIVAPAT SSNGASDFKQ LKLAYETNPL DGSCDQDLML RSQPLLVTYH
AETINRLMVA LRPPESVRLK QLTNAAMMKY EDIKKISTAG LHRAMQMRKR FKIDLKVLPT
TLNIPAFGDI SRAKSMLVMD FGMLRIKSEE FKDKSMLHVD ELYKKSEDER CRILMNDGYD
AMNVTLKSLK ILFVEKDANG QFDLQKAEAL LEPTGIGILI RTAIADDVGI PKNQIKGTLP
DLTFNISERY LVQLLKLVSS IPMPPPDERN QTLQMWQENE HKYGSVRMQA PSEVSIDDEL
TVSSEGKSTD STTGSSSLSD YNEQVDFQII FLLNQIALDV YREEDKASKY FSLRVADVGM
ELRTRPLDMV MQCHVGTVEM LHHGYTVDDN SPLYLIRKGP SSQHLLHLDY RQADRENPFF
ASTFHSTEQW IELKVQPLCI NARQEALVDM QNFMHRLKDE IATLPAVAVP KIATPSKHAP
AAQIIIPTPK SKTSSQKGSK KSKKVDTVLF SMLRLRTRVS GLRVVLATSN GPISEIAVEG
LKVEMVQMIE KTKYFVRLES VAIDHFDSHS DYKRILSVVG DEMFRLECVQ FNIPAESKRL
DLLSQVEMML TIRFSQLRFI FLYYWLSRLL NWISPFQNAA QRTASYAGSA LQEGARTAVD
LLQDQDITRI KLDIVIDAPV IIVPANTQSS RALMVNFGQL IVKNQFRFCS ALSVDGVSTL
FDDINLKLDQ MKICRVLLDK DCWTLTRERQ LLKPITFVLA VQRNLSFATV KGIPSITVRG
QLPDIELGFT SDDYAVMMEI LNENLAELEP GPDLSATGGS LTTSNSGDKE AGAVKSSVLV
DVELVENSVA GEASNQPAGN VSGDKAARPP PYSSSSSSSS STSDSTVQVE LGFEIDHLSA
VLSKCAKRDE AFAKLDEEIC PADPLAGLQL RSIKLQARLF TNGCMSASVV VQGLEVEDQR
TGDIGIRKLL DCMPGMQNSA VLTADYKTSV AAPRIALVNL NKFFLCLSVD FLLELSSFFT
WTPTDRFADS LAERALAQST SRAKRSAAEQ IPAGVQPPAD LLQINTQING IQVILVEDCR
RPDSTNAMFL EFQASVDIDS TADEMNMQGS VENLEMYSDQ FAMFQRGMYK YPILSPCRMA
MNYKKSSNEE SAKVIMPELK LRVSPAAIHH FSTTLAEMTR NKAEVTVSTV EQIPAPVDVW
SEKLVTSQGF WFLKEKDDID YGCECDELMI VDDENSERSL KKTQRLVFDI PSVFMMLEAD
SGRRTVPMIY LHCGMEGEVY DWSSLLWVSS TVTCIAWYFN DRNNAWEPVL EPIVEKMTPR
PWKFRALVNQ SDPFDSKDGQ EEEQLSPKAR MTVSISSDEA FSAAAHRRLE AKVDSSKPLE
PYLLINKLGL PIMIGSTEHF DVPDDYINKP LMHGESVSLI GKVDTSCLGA LELQDATPSM
YLHIQIPELN VTRILDVSHA GLRLYHIQVR ATADKKWKFL VDVSTSMGNR VIVLRSAVMF
YNFLPFDVEI YQKTDSNFRD AILLKADGGC ASPALSDVNQ GNTEFCVKPI DDSYDVSIRG
INWPVLENDN RSVLLECCFG HSGVLYIQAS AEHVFCLSES SNVLKQSQDV FNIHLQAPLV
FLNLLHIQVL LSVETLEPSE KITLSSSESR SLFHIHPSKS KIKLTLFDSK NAKLRKSCTL
DLSSALNEVN VLSFRAFEDD PELNLGLMKA EDNSKCVLSL FSPIWLVNST GLPLECKEAR
SNCGRTFQLP VQTDVVPVML SLSRKKFFEK KNARLKVCDS EWSSAFPLDT VGSAGRITCA
HSKLKSYDVS VTSRLSEFGL TKICSFVPFY MVKNVSMFDI EVRQVDEDSW IRVNVNQCVG
IWPNQNRRLI YCARYVGTVE ESQHFLITDT AEMFATIANQ HIGVYVSCNV SENSVIVTLE
KYQQGMIPLL IINALQSYDL LYGQEASNNE PKVLKRGMCV YYAWESLLLK RSLAWTCGNA
KDTWTLQSTF GEMFPDRDVA CYYVAFSDGS QRVLLFTDDA TVCTVAKQVY DLEIADKEFL
ISFQGVGLSL VNDRIGHEIA YVSLKSTGVI WEQKKKRFRA FSVKYCNLLE AAYMKYLNDL
RTKQRVDSCF QVHKLLVDFA DMKILKPDPR EIRRSFQSGF SLQYRVSPHD VQVHLKINSF
QIDNQIPGCV FNTVFSRAPI PKSIASESVP KPFIEVTFIM RNANETIPYV QYFKILIQEM
TLKADNGFLE SLMDFFNASS VDKEDTDKEK FERDWNFVQQ DLGAYALTAS SDEQKAFYNL
LHFSPLKLHL SYSQGGAAAT EGETQSIFQT HILGLLLKSI GVTMTEVQDV VFKLPYFERD
CMFLGKQALF NEVYNHYFKQ AVKQIFVLVL GLDVIGNPFG LMRDLSTGVE QLFYEPIQGA
IEGPEEFAEG LALGMRSLLG HTVGGAAGAV SKITGTLGKG IAALTFDADY QQKRQRMMNR
RTGDLSGVAQ SGTGALLEVF DGVTGVFTKP IEGAREEGAL GFAKGLGKGL IGAVTRPITG
VVDFASASLD ALKKATEVLE EVKPTRPSRY IALDRIIRPY TFYEAEGNKL LMDLEKGKYR
TTDSYVVHQP LTERNDQFLM ATDQRILHIM ISDFTGSFTV TWSIPYSEMK GQPKIDSLKL
TIQCKEKSSK WLSSKKNEVS GKSVFFLDES SLLCFYEKMS EVLLSSKSE
//
